Clinical trials: Labor, Obstetric
Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure
Automated Versus Manual Control Of Oxygen For Preterm Infants On Continuous Positive Airway Pressure In Nigeria
One in ten babies are born preterm (<37 weeks gestation) globally. Complications of prematurity are the leading cause of death in children under 5 years, with the highest mortality rate in Sub-Saharan Africa (SSA).
- Conditions
- Neonatal Respiratory Distress Related Conditions, Neonatal Respiratory Failure, Prematurity, Oxygen Toxicity
- Trial name
- NCT05508308
- Testing
- OxyMate, Manual oxygen control
- Where
- 2 sites in Nigeria
- Volunteers
- 49 people
- Sponsor
- Murdoch Childrens Research Institute
Preterm Birth, Obstetric Labor, Premature
Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor With Progesterone
The purpose of this study is to determine if the use of 250 mg of intramuscular progesterone biweekly can reduce the incidence of preterm labor in patients with an episode of threatened preterm labor during the current pregnancy.
- Trial name
- NCT01317225
- Testing
- 17 α hydroxyprogesterone caproate
- Where
- Panama
- Volunteers
- 80 people
- Sponsor
- Saint Thomas Hospital, Panama
Fetal Membranes, Premature Rupture, Preterm Birth Complication
Emotional Support for Women Experiencing PPROM
Preterm Prelabour Rupture of the Membranes is a pregnancy complication affecting 3% of all pregnancies. Outcomes for both the mother and baby are variable including: preterm delivery, fetal infection, cord prolapse, abruption as…
- Trial name
- NCT06262308
- Testing
- Psychological intervention along Cognitive Behavioural Therapy principles
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- King's College London
Pregnancy Preterm
Melatonin Levels in Preterm and Term Newborn Infants
The general goal of the present study is to examine the developmental changes caused by melatonin in preterm and term newborns. The major brain lesions associated with cerebral palsy and cognitive impairment in preterm infants…
- Trial name
- MELIP (NCT01340417)
- Testing
- Measurements of melatonin levels in urine, blood, milk.
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preterm Birth, Developmental Delay
The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years
Objective of the study: To examine cognition, motor function, executive functions, speech and language development, behaviour, psychosocial functioning,academic achievement, physical morbidities and growth of MLPTI at the age of…
- Conditions
- Preterm Birth, Developmental Delay, Growth Delay
- Trial name
- NCT05990582
- Testing
- CBCL, SDQ, CCC-2-NL
- Where
- Netherlands
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Noordwest Ziekenhuisgroep
Retinopathy of Prematurity, Myopia
Prematurity and Ophthalmological Changes
Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity
- Trial name
- NCT06452524
- Testing
- axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Prematurity, Eye Fundus
Benefit of Singing in the Care of Premature Children Undergoing Screening for Retinopathy of Prematurity in the Neonatology and Neonatal Resuscitation Unit of the Dijon University Hospital
As part of the regular procedure for premature births, premature infants undergo several screening examinations, including an examination of the fundus.
- Trial name
- Voix Chantée (NCT03830580)
- Testing
- Positive stimulation (singing)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Premature Birth
Investigation of Administration of MCT/ω-3 Fatty Acids is Towards Anti-inflammatory Related Fatty Acid Profile in Preterm Neonates.
Intravenous administration of pure soybean oil emulsions high in linoleic acid may lead to inflammation and lipid peroxidation in preterm neonates.
- Trial name
- MCT/ω-3 FA (NCT04586608)
- Testing
- MCT/ω-3 fatty acids, soybean oil-based IVFE
- Where
- Greece
- Volunteers
- 92 people
- Sponsor
- Iaso Maternity Hospital, Athens, Greece
Prematurity
Electrocardiography Versus Pulse Oximetry for Newborn Heart Rate Determination
The goal of this study is to compare the time required for accurate heart rate measurement of the preterm newborn when using pulse oximetry versus electrocardiography leads.
- Trial name
- NCT01256346
- Testing
- Apparatuses
- Where
- United States
- Sponsor
- University of Oklahoma
Prematurity; Extreme
Pulmonary Vascular Disease and Cardiac Performance in Extreme Preterm Infants
Pulmonary vascular disease and cardiac performance in extreme preterm infants: A prospective cross-sectional study
- Trial name
- NCT04114435
- Testing
- Echocardiography
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Preterm
Early Childhood (2-year) Outcomes Among Former VLBW From the ReDiMOM Trial
The goal of this study is to determine the long-term outcomes associated with an economic intervention that was provided to encourage mother's of very premature infants to provide mother's own milk.
- Trial name
- NCT07702318
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- Rush University Medical Center
Periodontal Diseases, Premature Birth
Periodontal Infection and Prematurity Study
This research project is a multi-center double-blind, parallel, randomized, controlled clinical trial design comparing the efficacy of dental scaling and root planing to control treatment (superficial cleaning) for the prevention…
- Trial name
- NCT00116974
- Testing
- Scaling and root planing
- Where
- United States
- Volunteers
- 2,100 people
- Sponsor
- University of Pennsylvania
Premature Birth
Cleanser Versus Only Water
The aim of this study is to determine the effect of the newborn's first bath with a cleaning product and only water on the barrier function of the skin.
- Trial name
- NCT04720989
- Testing
- Bathing With Baby Cleanser and water, Bathing With only Water
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Prematurity
Preterm Donor Human Milk Supplementation of Mother's Own Milk in VLBW Infants
This prospective randomized controlled trial aims to investigate whether feeding very low birth weight (VLBW) infants with Mother's own milk (MOM) supplemented with either preterm (PDM) or term donor milk (TDM), when MOM is…
- Trial name
- NCT05675397
- Testing
- donor human milk
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Behavioral Assessment of Children, Early Intervention
PaREnting ProgrAm to Enhance PREterm Infants' Health and Development (PREPARE Trial)
Preterm infants are at high risk of developmental delay or disabilities and they do benefit from early intervention programs. Many programs aiming at improving preterm infants' developmental outcome have been proposed with mixed…
- Trial name
- PREPARE (NCT04783220)
- Testing
- Comprehensive structured parent intervention
- Where
- Lebanon
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Intraventricular Hemorrhage (IVH), Bleeding in the Brain
Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial
The purpose of this multicenter trial is to determine if indomethacin prevents bleeding in the brain of very low birth weight preterm infants.
- Conditions
- Intraventricular Hemorrhage (IVH), Bleeding in the Brain, Prematurity, Very Low Birth Weight Infants
- Trial name
- NCT00033917
- Testing
- indomethacin
- Where
- 3 sites in United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Yale University
Premature Infant
Amino Acids Profiles in Premature Infants Receiving Nutritional Support
The aim of this study is to investigate the changes of amino acid metabolic profiles in different nutritional stages of preterm infants and determine the effects of nutritional intervention on the amino acid metabolic status of…
- Trial name
- NCT03100305
- Testing
- Collection of blood and urine
- Where
- China
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Infant, Premature, Anemia
Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants
The purpose of this study was to determine whether restrictive guidelines for red blood cell (RBC) transfusions for preterm infants can reduce the number of transfusions without adverse consequences.
- Conditions
- Infant, Premature, Anemia, Intracranial Hemorrhages, Leukomalacia, Periventricular
- Trial name
- NCT00369005
- Testing
- Red blood cell transfusion guidelines
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Hypoxic Ischaemic Encephalopathy (HIE), Premature Birth
Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care
The goal of this behavioral-interventional study is to learn if the Abecedarian Approach implemented virtually for children ages 0-5 with a history of Hypoxic Ischaemic Encephalopathy (HIE) and/or premature birth produces the…
- Conditions
- Hypoxic Ischaemic Encephalopathy (HIE), Premature Birth, Cerebral Palsy, Neurological Disorder
- Trial name
- NCT06643598
- Testing
- Abecedarian Approach
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- University of Wisconsin, Madison
Preterm, Oral Feeding Performance
Effect of Maternal Voice on Physiological Indicators and Feeding Performance
This study aimed to determine the effect of maternal voice on physiological indicators and oral feeding performance in preterm infants.
- Trial name
- NCT07068581
- Testing
- Maternal voice, Control Group (standard feeding )
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Acibadem University
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