Clinical trials: Labour
Pregnancy, Labour Onset and Length Abnormalities
Role of Maternal Physical Exercise on Spontaneous Labor Onset
Evaluate the effects of the practice of maternal physical exercise on the term of pregnancy as a method to enhance spontaneous labor.
- Trial name
- NCT02460185
- Testing
- Study group: Maternal Physical Exercise
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Norte
HIV Infections
Efficacy of Nevirapine Compared to ZDV + 3TC Administered in Labor and Again at Postdelivery in HIV Positive Women
The primary objective of the study was to evaluate the efficacy of nevirapine versus ZDV+3TC (Zidovudine + Lamivudine), when administered in labor and again at postdelivery, in reducing peripartum mother to child transmission of…
- Trial name
- NCT02181933
- Testing
- Nevirapine, Zidovudine (ZDV), Lamivudine (3TC)
- Volunteers
- 2,648 people
- Sponsor
- Boehringer Ingelheim
Fetal Intrauterine Distress First Noted During Labor and or Delivery in Liveborn Infant, Team Based on Their Existing Guidelines and the Woman Consents to Have EFM and EFM is
Use of Decision Support in the Management of Labour
In women judged to require continuous electronic fetal heart rate monitoring (EFM) during their labour, does the addition of decision support software to aid the interpretation of the intrapartum cardiotocogram (CTG) reduce the…
- Conditions
- Fetal Intrauterine Distress First Noted During Labor and or Delivery in Liveborn Infant, Team Based on Their Existing Guidelines and the Woman Consents to Have EFM and EFM is, Possible
- Trial name
- INFANT (NCT02010710)
- Testing
- INFANT software
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 47,062 people
- Sponsor
- University College, London
Postpartum Bleeding
When and How to Administer Oxytocin for Active Management of Third Stage of Labour
To compare the efficacy of the route and timing of oxytocin administration for Active management of third stage of labour (AMTSL).
- Trial name
- NCT01954186
- Testing
- intravenous & intramuscular oxytocin, after delivery of the fetus & when anterior shoulder seen
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Etlik Zubeyde Hanim Womens' Health and Teaching Hospital
Occupational Health, Sick Leave
Effects of Regulatory Tools on Work Environment and Employee Health
This study evaluates the effects of the Labour Inspection Authority's regulatory tools on workplace exposures to prevent employee ill health.
- Conditions
- Occupational Health, Sick Leave, Occupational Exposure
- Trial name
- NCT03855163
- Testing
- Inspection visits, Guidance workshops, Online risk assessment tool
- Where
- 130 sites in Norway
- Volunteers
- 2,555 people, healthy volunteers welcome
- Sponsor
- National Institute of Occupational Health, Norway
Arrested Labor
Bicarbonate Given During Dystocic Labor
Dystocic deliveries and the use of bicarbonate
- Trial name
- NCT02805387
- Testing
- Treatment
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Pain During Labour
Tramadol for Labour Analgesia in Low Risk Primiparous Women
Tramadol is a centrally acting synthetic analgesic used to treat moderate to moderately severe pain. It has been previously evaluated as a method to reduce pain during labour, but there is always some fear related to its effects…
- Trial name
- NCT01889979
- Testing
- Tramadol
- Where
- Panama
- Volunteers
- 100 people
- Sponsor
- Saint Thomas Hospital, Panama
Mental Disorder
Improving Integration of Mentally Burdened Young Adults in the Labour Market
Young adults who do not successfully transition from compulsory education to upper secondary level are at increased risk of developing mental illness, as compared with their working peers.
- Trial name
- inklusiv (NCT03328286)
- Testing
- Weekly group meeting w/psychotherapist
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Fetal Distress, Birth Asphyxia
Effect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes
Introduction Birth asphyxia is one of leading causes of neonatal mortality in Uganda. It is associated with long term neuro-developmental complications among the babies that survive.
- Trial name
- Intra-O (NCT04043299)
- Testing
- 100% Oxygen, 21% oxygen
- Where
- Uganda
- Volunteers
- 1,108 people
- Sponsor
- Makerere University
Pregnancy Related, Fever
Assessment of Labour Progress by Intrapartum Ultrasound
Assessment of labor progress via digital exams is considered the standard of care in most delivery rooms. However, this method can be stressful, painful and imprecise and multiple exams increase the risk for chorioamnionitis.
- Conditions
- Pregnancy Related, Fever, Chorioamnionitis, Labor Complication
- Trial name
- NCT04651309
- Testing
- Transperineal Ultrasound
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Gestational Diabetes Mellitus (GDM)
The Feasibility Of Expectant Management Versus Induction At 38 Weeks Among Individuals With Gestational Diabetes Mellitus: A Randomized Controlled Pilot Trial (EAGER Pilot Trial)
The EAGER pilot trial is designed to assess the feasibility of a Canadian, multicentre prospective randomized open-label blinded end-point (PROBE) clinical trial addressing whether induction of labour (IOL) at 38 weeks' gestation…
- Trial name
- EAGER Pilot (NCT06641141)
- Testing
- Induction of Labour
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- Ottawa Hospital Research Institute
Pain During Labour, Fear of Childbirth
The Effects of the Use of Virgin Mary Herb in Childbirth
This is a study to see if the use of virgin mary herb during birth has an effect on fear, pain and duration during birth. Virgin mary herb is a dry plant and it is believed that when added to water during birth, it makes birth…
- Trial name
- EVMHUBDPFC (NCT06824558)
- Testing
- primiparous pregnant woman following virgin mary, primiparous pregnant
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Labour Induction
Vaginally Administered Versus Per Oral Misoprostol in Induction of Labour
The purpose of this study is to investigate the effectiveness and safety of vaginally administered misoprostol (Misodel) versus per orally administered misoprostol (Cytotec) in induction of labour in nulliparous women.
- Trial name
- NCT02539199
- Testing
- Misoprostol, modified-release pessary, Misoprostol, per-oral tablets
- Where
- 5 sites in Finland
- Volunteers
- 270 people
- Sponsor
- Tampere University Hospital
Urinary Tract Infection in Pregnancy, Urinary Tract Infection Following Delivery
Postnatal Prevalence of Bacteriuria in Women With Catheter Versus no Catheter in Labour
Catheterisation is an accepted tool in intrapartum bladder care and indwelling catheters are used routinely before elective caesarean sections.
- Conditions
- Urinary Tract Infection in Pregnancy, Urinary Tract Infection Following Delivery, Catheter Infection
- Trial name
- NCT03914144
- Testing
- Catheter insertion
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Induced; Birth, Delivery Complication
The Norwegian Induction Project: a Pilot for a Prospective National Audit
The worldwide rate of induction of labour has been steadily increasing over the last 15 years, a trend that is reflected in Norway.
- Conditions
- Induced; Birth, Delivery Complication, Indications for Care in Pregnancy; Labor; and Delivery
- Trial name
- NCT03730220
- Where
- Norway
- Volunteers
- 1,846 people
- Sponsor
- Oslo University Hospital
DELAYED LABOUR
High Dose Versus Low Dose Oxytocin for Augmentation of Delayed Labour in Obese Women
Obesity is one of the biggest public health problems of the 21st century as it increases the risk of many co-morbid medical conditions.
- Trial name
- NCT03604874
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 202 people
- Sponsor
- Assiut University
Labor Complication
Traditional WHO Partograph and Korle-Bu Modified WHO Partograph for Uncomplicated Labour
Brief Background: The partograph is a graphical representation of the events in the first stage of labour. It is an instrument used in monitoring the well being of both the pregnant woman and her fetus (es) as they go through the…
- Trial name
- NCT05837559
- Testing
- Korle-Bu Modified WHO Partograph for Uncomplicated Labour
- Where
- Ghana
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Preterm Birth, Preterm Premature Rupture of Membrane
Cerclage After Full Dilatation Caesarean Section
CRAFT-OBS: Observational Study; To evaluate subsequent pregnancy risk of preterm birth in women with a history of previous caesarean in established labour.
- Conditions
- Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Spontaneous Labor With Preterm Delivery
- Trial name
- CRAFT (NCT04110704)
- Testing
- Insertion of transvaginal cerclage
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
ST-elevation Myocardial Infarction
Follow-up of Patients Bound for PCI After Implementation of a Helicopter Emergency Medical System
This study compares patients bound for Percutaneous Coronary Intervention (PCI) who were transported by either ground ambulance or emergency medical helicopter.
- Trial name
- NCT02512991
- Testing
- Helicopter Emergency Medical Service
- Volunteers
- 1,604 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Preterm Pregnancy, Preterm Birth
Prediction of the Onset of Term and Preterm Labour
This study will collect samples from pregnant women in order to identify biomarkers that relate to onset of spontaneous preterm labour.
- Conditions
- Preterm Pregnancy, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane
- Trial name
- PREDICT (NCT04590677)
- Testing
- Samples required from group 1 (procedure within observational study), Samples required from group 2 (procedure within observational study)
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust