Clinical trials: Labour
Virtual Reality, Induction of Labor Affected Fetus / Newborn
VR Glasses During Induction of Labour for Pain and Anxiety Relieve
In the current study, The investigators aim is to test the distraction affect of "Virtual Reality" (VR) technology on pain and anxiety in pregnant women who undergo through an induction of labour with an extra-amniotic balloon…
- Conditions
- Virtual Reality, Induction of Labor Affected Fetus / Newborn, Extra Amniotic Balloon
- Trial name
- NCT05187247
- Testing
- Virtual Reality glasses
- Where
- Israel
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Pregnancy
Relevance of Ultrasound Screening for Foetal Macrosomia
Management of fetal macrosomia is based on a suspicion of macrosomia (no certainty before birth). This management is an artificial induction of labour for an earlier delivery and therefore a lower fetal weight gain.
- Trial name
- USmacro (NCT04443205)
- Testing
- Data record
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- CHU de Reims
Obstetric Labour, Premature
A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor
The study's primary objective is to demonstrate the superiority of retosiban to prolong pregnancy and improve neonatal outcomes compared with placebo.
- Trial name
- NEWBORN-1 (NCT02377466)
- Testing
- Retosiban IV infusion
- Where
- 50 sites in United States, Canada and 3 more
- Volunteers
- 25 people
- Sponsor
- GlaxoSmithKline
Gestational Diabetes Mellitus (GDM)
The Feasibility Of Expectant Management Versus Induction At 38 Weeks Among Individuals With Gestational Diabetes Mellitus: A Randomized Controlled Pilot Trial (EAGER Pilot Trial)
The EAGER pilot trial is designed to assess the feasibility of a Canadian, multicentre prospective randomized open-label blinded end-point (PROBE) clinical trial addressing whether induction of labour (IOL) at 38 weeks' gestation…
- Trial name
- EAGER Pilot (NCT06641141)
- Testing
- Induction of Labour
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- Ottawa Hospital Research Institute
Induction of Labour
REgistry of MisOprostol 200 µg Vaginal dElivery System
The design of the study is post-marketing, observational, multi-centre and open-label. The study does not provide treatment; only patients to whom misoprostol 200 µg vaginal delivery system (VDS) is prescribed may be included.
- Trial name
- REMOVE (NCT02242214)
- Testing
- Misoprostol
- Where
- Netherlands
- Volunteers
- 106 people
- Sponsor
- Ferring Pharmaceuticals
RSV Infections, RSV Immunisation
A Clinical Trial on Safety in Pregnant Women and How Well the Infant is Protected Against RSV-associated Lower Respiratory Tract Infection When the Pregnant Woman Receives the Approved RSV Vaccine Compared to a Placebo.
Respiratory syncytial virus (RSV) is a virus that often affects children during childhood. Even though most cases of RSV are mild, it can cause serious disease and even death - especially in very young babies, babies born too…
- Conditions
- RSV Infections, RSV Immunisation, Preterm Labour
- Trial name
- NCT06955728
- Testing
- Vaccine
- Where
- 11 sites in Ghana, Kenya and 2 more
- Volunteers
- 13,000 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Induced; Birth, Delivery Complication
The Norwegian Induction Project: a Pilot for a Prospective National Audit
The worldwide rate of induction of labour has been steadily increasing over the last 15 years, a trend that is reflected in Norway.
- Conditions
- Induced; Birth, Delivery Complication, Indications for Care in Pregnancy; Labor; and Delivery
- Trial name
- NCT03730220
- Where
- Norway
- Volunteers
- 1,846 people
- Sponsor
- Oslo University Hospital
Labour Duration and Metoclopramide
Metoclopramide and the Length of First Stage of Labor , a Randomized Controlled Trial
Reducing the length of labor is a highly desirable goal of intrapartum care, both from a perspective of maternal and fetal well-being and for the providers of the birth services.
- Trial name
- NCT04969120
- Testing
- Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fetal Distress, Birth Asphyxia
Effect of Intrapartum Oxygen Administration on Fetal and Early Neonatal Outcomes
Introduction Birth asphyxia is one of leading causes of neonatal mortality in Uganda. It is associated with long term neuro-developmental complications among the babies that survive.
- Trial name
- Intra-O (NCT04043299)
- Testing
- 100% Oxygen, 21% oxygen
- Where
- Uganda
- Volunteers
- 1,108 people
- Sponsor
- Makerere University
Induction of Labour
Trial Of Misoprostol And Dinoprostone Vaginal Pessaries for Cervical Priming (TROMAD Study)
Most studies of labour induction with misoprostol used doses higher than 25mg and intervals of 3-4 hours. We studied a low-dose regime of 25mg misoprostol and compared its efficacy as single dose or double dose with dosing…
- Trial name
- NCT00299754
- Testing
- Misoprostol
- Where
- Singapore
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Neonatal Complication, Labor (Obstetrics)--Complications
Can the Use of a Next Generation Partograph Improve Neonatal Outcomes? (PICRINO)
The overall aim is to evaluate the impact of the use of two different guidelines for monitoring labor progress, the WHOs LCG versus standard care, on neonatal and maternal outcomes.
- Trial name
- NCT05560802
- Testing
- WHOs Labour care guide
- Where
- 24 sites in Sweden
- Volunteers
- 120,000 people
- Sponsor
- Linkoeping University
Pain During Labour, Fear of Childbirth
The Effects of the Use of Virgin Mary Herb in Childbirth
This is a study to see if the use of virgin mary herb during birth has an effect on fear, pain and duration during birth. Virgin mary herb is a dry plant and it is believed that when added to water during birth, it makes birth…
- Trial name
- EVMHUBDPFC (NCT06824558)
- Testing
- primiparous pregnant woman following virgin mary, primiparous pregnant
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Pregnancy, Labour Onset and Length Abnormalities
Role of Maternal Physical Exercise on Spontaneous Labor Onset
Evaluate the effects of the practice of maternal physical exercise on the term of pregnancy as a method to enhance spontaneous labor.
- Trial name
- NCT02460185
- Testing
- Study group: Maternal Physical Exercise
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Norte
Preterm Labor Without Delivery
Tocolysis in Prevention of Preterm Labor
Preterm birth is defined as birth before 37 completed weeks of gestation .it occurs in 11.1%of birth globally affecting an estimated 14.9 million babies every year .
- Trial name
- NCT03298191
- Testing
- Magnesium Sulfate, Ritodrine, Calcium Channel Blockers
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
HIV Infections
Efficacy of Nevirapine Compared to ZDV + 3TC Administered in Labor and Again at Postdelivery in HIV Positive Women
The primary objective of the study was to evaluate the efficacy of nevirapine versus ZDV+3TC (Zidovudine + Lamivudine), when administered in labor and again at postdelivery, in reducing peripartum mother to child transmission of…
- Trial name
- NCT02181933
- Testing
- Nevirapine, Zidovudine (ZDV), Lamivudine (3TC)
- Volunteers
- 2,648 people
- Sponsor
- Boehringer Ingelheim
Prolonged Labor
Electronic Partograph: A Way of Improving Partograph Use During Labour Monitoring Process in Selected District Hospitals in Bangladesh
Background (brief): 1. Burden: Abnormal prolonged labour and its effects are important contributors to maternal and perinatal mortality and morbidity worldwide.
- Trial name
- NCT03509103
- Testing
- Electronic Partograph
- Volunteers
- 1,012 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Induction Time, Apgar Score
The Balloon Project for Birth Induction
The use of prostaglandin E2 (PGE2) for induction of labour in women with unfavourable cervices is well-established1. There are, however, potential side effects to prostaglandins, in particular the risk of uterine hypertonicity…
- Conditions
- Induction Time, Apgar Score, Admission to Neonatal Unit, Vaginal Delivery
- Trial name
- NCT01255839
- Testing
- Double Balloon, Minprostin
- Where
- Denmark
- Volunteers
- 825 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Premature Rupture of Fetal Membranes
Intravenous Papaverine for Term Prelabor Rupture of Membranes
This randomized, double-blind, placebo-controlled trial evaluates whether intravenous papaverine, administered as an adjunct to oxytocin, shortens the time to delivery in women with term premature rupture of membranes (PROM).
- Trial name
- NCT07826533
- Testing
- Papaverine
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Wolfson Medical Center
Labor Complication
Traditional WHO Partograph and Korle-Bu Modified WHO Partograph for Uncomplicated Labour
Brief Background: The partograph is a graphical representation of the events in the first stage of labour. It is an instrument used in monitoring the well being of both the pregnant woman and her fetus (es) as they go through the…
- Trial name
- NCT05837559
- Testing
- Korle-Bu Modified WHO Partograph for Uncomplicated Labour
- Where
- Ghana
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Ghana Medical School
Obstetric Labour, Premature
A Randomized Study Comparing the Efficacy and Safety of Retosiban Versus Atosiban for Women in Spontaneous Preterm Labour
The primary objective of this study is to demonstrate the superiority of retosiban to prolong pregnancy in females with spontaneous preterm labor compared with atosiban.
- Trial name
- NCT02292771
- Testing
- Retosiban, Atosiban
- Where
- 21 sites in Belgium, Germany and 7 more
- Volunteers
- 97 people
- Sponsor
- GlaxoSmithKline