Clinical trials: Laser
Rhegmatogenous Retinal Detachment
Clinical Trial of Cryotherapy Versus Postoperative Laser Photocoagulation
The purpose of this randomized clinical trial was to compare reattachment rates among patients with rhegmatogenous retinal detachment who underwent scleral buckle surgery with retinopexy by cryotherapy versus postoperative (one…
- Trial name
- NCT01068379
- Testing
- criopexy, laser
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Irreversible Pulpitis (Toothache)
Laser Assisted Pulpotomy Versus MTA Pulpotomy in Permanent Teeth With Irreversible Pulpitis
This study compares two methods used during full pulpotomy, a treatment for teeth with deep tooth decay that has exposed the dental pulp.
- Trial name
- NCT07761962
- Testing
- Diode laser full pulpotomy, Sodium hypochlorite pulpotomy
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Vulvovaginal Atrophy
Use of Fractional CO2 Laser for the Treatment of Vulvovaginal Atrophy: a Double-blinded Randomized Placebo-controlled Clinical Trial.
Purpose of the trial is to study the efficacy of fractional laser in alleviating genitourinary symptoms in menopausal women. Primary outcome of the study is the efficacy of the laser procedure, intended as the amelioration of the…
- Trial name
- CO2VVA (NCT04021966)
- Testing
- Vaginal laser application
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- prof. dr. Jan Deprest
Low Level Laser Therapy
Effect of Low-level Laser Therapy on Orthodontic Tooth Movement
The objective of this trial is to investigate the effect of low-level laser therapy (LLLT) on orthodontic tooth movement during maxillary molar distalization over 12-week observation period.
- Trial name
- NCT05550168
- Testing
- Low Level Laser therapy
- Where
- Cyprus
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Bleomycin Adverse Reaction
Comparison Between Diode Laser and Bleomycin in Treatment of Hemangioma
Assessment of the Effectiveness of Bleomycin Intralesional Injection and Diode Laser on Management of Infantile Hemangioma., with regard to : Clinically based on Change in the Size and Color of Hemangioma.
- Trial name
- NCT06510829
- Testing
- Diode laser
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myopia, Astigmatism
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
The purpose of the study is to compare the results of LASIK surgery when using two versions of a femtosecond laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT01365728
- Testing
- LASIK with the iFS femtosecond laser
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Cicatrix, Hypertrophic, Burns
Laser Therapy for Pediatric Burn Scars
A new era of outcomes for pediatric burn patients has begun as burn care continues to improve. Unfortunately, complete restoration of burn-injured skin may be limited by the development of hypertrophic scarring.
- Trial name
- NCT02707627
- Testing
- Laser Therapy
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Class II Division 1 Malocclusion
Effect of Low-level Laser Therapy During Maxillary Molar Distalization Using a Skeletally Anchored Appliance
study will be directed to evaluate the effect of low-level laser therapy during maxillary molar distalization using a skeletally anchored appliance
- Trial name
- NCT05465473
- Testing
- Distalization
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Retinopathy of Prematurity, Myopia
Prematurity and Ophthalmological Changes
Ophthalmological differences in school-aged children with and without a history of retinopathy of prematurity
- Trial name
- NCT06452524
- Testing
- axial length (AU) and anterior chamber depth (ACD), optical coherence tomography (OCT)
- Where
- Turkey (Türkiye)
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Vitreoretinopathy, Coats' Disease
DEXTENZA in Pediatric Patients Following Retinal Surgery or Laser Treatment Under Anesthesia
The Tender Study is a prospective, open-label, single-center, randomized, investigator-initiated clinical study seeks to investigate the safety and efficacy of the DEXTENZA insert in pediatric patients following retinal surgery…
- Conditions
- Vitreoretinopathy, Coats' Disease, Exudative Retinopathy, Lattice Degeneration
- Trial name
- NCT05620901
- Testing
- Dextenza 0.4Mg Ophthalmic Insert, Pred Forte
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lejla Vajzovic, MD, FASRS
Dental Caries
Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser
The objective of this clinical study is to evaluate whether the use of the new CO2 - 9.3μm short-pulsed laser increases the caries resistance of occlusal pit and fissure surfaces in patients in addition to fluoride therapy.
- Trial name
- LaserFissure (NCT02357979)
- Testing
- Laser, Fluoride
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Benign Skin Tumor, Basal Cell Carcinoma
Study to Examine Lesions of the Skin Using Confocal Laser Microscopy
Using ex-vivo confocal laser scanning microscopy, a reliable statement can be made about the extent, histological structure and possible significance of a skin change without having to send tissue samples for demanding and…
- Conditions
- Benign Skin Tumor, Basal Cell Carcinoma, Melanoma, Squamous Cell Cancer
- Trial name
- NCT06598137
- Testing
- Ex vivo confocal laser microscopy
- Where
- Germany
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Impacted Third Molar Tooth
Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.
The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction.
- Trial name
- NCT06262945
- Testing
- Diagnoses, traditional osteotomies, platelet rich fibrin
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beste Erismen
Solar Lentigines
Side Effects of Q-Switched Ruby Laser for the Treatment of Lentigines in Light and Dark Skin Types
The purpose of this study is a comparison of efficacy and side effects of Q-switched Ruby laser treatment for solar lentigines in two different skin types II and IV.
- Trial name
- NCT00386204
- Testing
- Q-switched Ruby Laser
- Where
- Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Enamel Demineralization
Comparative Assessment of Adhesive PreCoated (APC) Flash-free and Conventional Brackets and the Effects on Enamel Demineralization and Periodontal Health
Adhesive PreCoated (APC) flash-free brackets have been recently introduced, with no need of flash removal step. Evaluation of APC and conventional brackets and their effects on enamel demineralization and periodontal health.
- Trial name
- NCT07752290
- Testing
- Group A, Group B
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Dental Trauma
Laser Doppler Flowmetry in Assessing the Vitality of Traumatised Teeth
Teeth injuries are considered one of the most challenging events that occur in dentistry, especially in children. After an injury, there is a possibility that the blood supply to the tooth may become affected and compromised…
- Trial name
- NCT03005197
- Testing
- Laser Doppler Flowmetry
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Reversal of Local Anesthesia in Children
Phentolamine Mesylate vs. Diode Laser for Anaesthesia Reversal
"Randomised three-arm trial comparing phentolamine mesylate (OraVerse), 650-nm diode laser and no intervention for accelerating reversal of soft-tissue anaesthesia after 4% articaine (1:100,000 epinephrine) buccal infiltration in…
- Trial name
- RCT (NCT05473858)
- Testing
- OraVerse Injectable Product, diode laser
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- sara nabil
Malocclusion, Angle Class II
Photobiomodulation of Orthodontic Mini-implants by a 635nm Diode Laser
The study aimed to estimate clinically an influence of 635nm diode laser on the primary and secondary stability of orthodontic mini-implants placed in a maxilla, to assess mini-implants failure rate (mini-implant loss) and to…
- Trial name
- NCT04170127
- Testing
- Irradiation of implants with 635nm laser
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Acne Vulgaris
Combined Low-Dose Isotretenion and Long-Pulsed 1064 ND-YAG Laser in the Treatment of Acne Erythema
Acne erythema consists of telangiectasia and erythematous papules, without a comedo, which occurs as a result of inflammatory acne.
- Trial name
- NCT05622253
- Testing
- Combined Low-Dose Isotretenion and Long-Pulsed 1064 ND-YAG Laser
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Zagazig University