Clinical trials: Local Anesthesia
Anesthesia, Local, Infant Conditions
Accuracy of Manual Palpation vs Ultrasound for Spinal Anesthesia
Although the current standard for lumbar puncture and spinal anesthesia is the use of manual palpation of surface landmarks to identify the correct interspace, performance of the procedure at too high of a level may increase the…
- Trial name
- NCT04757805
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nationwide Children's Hospital
Injection Site Irritation, Injection Site Bruising
Comparison of Subcutaneous Injection of Normal Saline and Bacteriostatic Saline
This is a randomized, double-blind, single-center clinical trial comparing normal saline and bacteriostatic saline subcutaneous injection within a single subject.
- Conditions
- Injection Site Irritation, Injection Site Bruising, Injection Site Discomfort, Benzoic Acid Adverse Reaction
- Trial name
- NCT05109000
- Testing
- Sodium Chloride 0.9% Inj, Bacteriostatic Sodium Chloride 0.9 % INJECTION VIAL (ML)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Jeffrey Alan Klein, MD
Sciatic Nerve AH, Peripheral Nerves US
Ultrasound Description of the Sciatic Nerve
Sciatic nerve blocks are frequently used for anesthesia or analgesia for surgery of the lower legs. Currently, if ultrasound is used to find the sciatic nerve, the leg must be raised to locate the nerve with the ultrasound probe…
- Trial name
- NCT00663715
- Testing
- Observation of the Sciatic Nerve
- Sponsor
- Children's Hospital of Philadelphia
Anesthesia
Impact of Ultrasound in Obstetric Anesthesia Central Blocks
This study aimed to evaluate the use of ultrasound in obstetric anesthesia, specifically for measuring epidural and intrathecal distances in pregnant women undergoing cesarean section.
- Trial name
- NCT06761222
- Testing
- The use of ultrasound in central blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ege University
Dental Anxiety, Pain
Effect of Therapeutic Play and Virtual Reality Glasses on Pain and Anxiety in Children
Background: A child's first dental experience plays a crucial role in treatment success and in fostering cooperation during future visits.
- Trial name
- NCT07375056
- Testing
- Intervention 1: Therapeutic Play Group, Intervention 2: Virtual Reality Glasses Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anxiety
Effectiveness of Mobile Applications During the Administration of Local Anesthesia in Pediatric Dentistry
To evaluate the mobile games' effect on patient acceptance of local anesthesia and decreasing dental pain and anxiety levels in pediatric patients.
- Trial name
- NCT04731181
- Testing
- mobile application (little lovely dentist).
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children, Anesthesia, Local
Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel.
The goal of this single-blinded randomized controlled trial is to compare pain perception during buccal infiltration using indirect EC spray and topical anesthesia and BC 20% topical gel, among seven to 10-year-old school…
- Conditions
- Dental Caries in Children, Anesthesia, Local, Injection Site Discomfort
- Trial name
- NCT06011005
- Testing
- Ethyl Chloride spray (group A), Benzocaine gel 20% (group B)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Anesthesia, Caudal
Caudal Block Versus Local Wound Infiltration for Inguinal Procedures
Single-centre observational study to analyse whether there is a difference in post-operative pain scores and set up time when comparing caudal block with local wound infiltration
- Trial name
- NCT04590027
- Volunteers
- 86 people
- Sponsor
- University Hospital Tuebingen
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pediatrics, Anesthesia, Local
Validation of Peripheral Perfusion Index in Predicting Successful Supraclavicular Brachial Plexus Block in Pediatrics
Few data are available for the PI as a tool for evaluation of peripheral block success in pediatric patients. Furthermore, there is currently no cut-off value defined for the accuracy of the PI in the detection of successful…
- Trial name
- NCT05815563
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Cairo University
Quadratus Lumborum Nerve Block, Erector Spinae Block
Comparison of ESP and QL Blocks for Postoperative Pain in Pediatric Appendectomy (ESP-QLB)
This prospective randomized controlled clinical trial aims to compare the analgesic effectiveness of the Erector Spinae Plane (ESP) block and the Quadratus Lumborum (QL) block in pediatric patients undergoing appendectomy.
- Trial name
- ESP-QLB (NCT07301528)
- Testing
- Quadratus Lumborum Block (QLB), Erector Spinae Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Zeycan Kahya
Hip Surgery, Hip Arthroplasty
The Quadro-Iliac Plane (QIP) Block in Hip Surgery
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including…
- Trial name
- QIP in hip (NCT07591311)
- Testing
- Fascia iliaca block (FIB)
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- San Giovanni di Dio Hospital
Situational Anxiety, Behavior
Impact of Therapy Dogs on Child Anxiety and Behavior During Local Anesthesia for Dental Procedures
Therapy dogs in dental offices might help anxious children during dental care. Therapy dogs might help children during injection of local anesthetic, when we inject numbing medication before working on the teeth.
- Trial name
- NCT06725134
- Testing
- Therapy dog presence, Standard-of-care basic behavior guidance
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anesthesia, Local
Type of Needle Bevel on Pain Perception in Children During Inferior Alveolar Nerve Block Anesthesia
fear of the discomfort that comes with anesthetic needle insertion. For dental local anesthesia, needles with a scalpel-designed bevel have been claimed to decrease pain elicited by injection.
- Trial name
- NCT06242743
- Testing
- Scalpel blade needles, standard blade needles
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Hams Hamed Abdelrahman
Regional Anesthesia
Analgesic Efficacy of Ultrasound-guided Bilateral Pecto-intercostal Plane Block in Pediatric Cardiac Surgery
The goal of this study is to compare patients outcome in two groups. the first group will be applied pecto-intercostal fascial block additional to general anesthesia and the second group will not.
- Trial name
- NCT06089798
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Anesthesia
URAISE: Ultrasound Regional Anaesthesia Interpretation Skill Evaluation
Prospective study based on psychometric principles.# To generate a validated test of ultrasound guided regional anaesthesia that can used to differentiate reliably between users of different skill levels.
- Trial name
- URAISE (NCT05668689)
- Testing
- Preliminary testing, Psychometric main study testing (Phase 5)
- Where
- 6 sites in United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Posterior Spine Surgery
Kyphoscoliosis Surgery: Blood Conservation and Analgesia
Since the first spinal fusion by Hibbs 1911, yet anesthesia for correction of scoliosis is challenging due to frequently associated co-morbidities, the extensive nature of surgery and liability for many complications.
- Trial name
- NCT03319563
- Testing
- Local anesthetic-epinephrine, Saline
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Mansoura University
Dental Anxiety, Pain Management
Effectiveness of Virtual Reality Technique on Children
Studying the effect of using virtual reality technique in managing pain, anxiety, and vital signs among pediatric dental patients.
- Conditions
- Dental Anxiety, Pain Management, Pediatric Dentistry
- Trial name
- NCT07722221
- Testing
- Conventional, Virtual reality
- Where
- Syria
- Volunteers
- 64 people
- Sponsor
- Latakia University
Dental Pain and Sensation Disorder, Dental Caries in Children
Local Anesthesia With Computerized Device for Restorative Procedures in Pediatric Patients
The aim of the present study is to assess if there are differences on perceived pain during local anesthesia performed with SleeperOne device or with a traditional syringe in pediatric patients.
- Trial name
- NCT05531435
- Testing
- local anaesthetic injection
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Molar Incisor Hypomineralisation
SleeperOne® 5 Intraosseous Anesthesia in MIH
This randomized split-mouth clinical trial evaluates whether computer-controlled intraosseous anesthesia delivered with the SleeperOne® 5 system reduces pain perception and dental anxiety compared with conventional local…
- Trial name
- CCLAD-MIH (NCT07741487)
- Testing
- SleeperOne® 5 Computer-Controlled Intraosseous Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara University