Clinical trials: Low Back Disorder
Low Back Pain, Spondylolysis
Feasibility of Using Functional Progression to Guide the Treatment of Adolescent Low Back Pain
The goal of the proposed research is to test the feasibility of a functional progression program to reduce cost and possible radiation exposure for adolescent athletes with low back pain.
- Conditions
- Low Back Pain, Spondylolysis, Spondylolisthesis
- Trial name
- NCT02861456
- Testing
- Standard Model of Care, Alternative Model of Care
- Where
- 4 sites in United States
- Volunteers
- 16 people
- Sponsor
- Nationwide Children's Hospital
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Adolescent Idiopathic Scoliosis, Low Back Pain
Spinal Stabilization Exercises for Low Back Pain in Adolescents With Idiopathic Scoliosis
1. Do spinal stabilization exercises demonstrate immediate and long-term effects of weight weeks of spinal stabilization exercises as measured by pain intensity and quality of life scores? 2.
- Trial name
- LBPAIS (NCT01550497)
- Testing
- supervised spinal stabilization exercises
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Crossbite, Malocclusion
Rapid Maxillary Expansion with Low Level Laser Therapy
The posterior crossbite is a common type of malocclusion that might affect the normal growth pattern. Early treatment is recommended by rapid maxillary expansion with different appliances.
- Conditions
- Crossbite, Malocclusion, Cross Bite, Maxillary Constriction
- Trial name
- NCT05586997
- Testing
- Bonded-Hyrax, Bonded Rapid Maxillary Expansion and low-Level Laser therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Research Centre, Egypt
Sciatica
Topiramate in the Treatment of Sciatica
This study will test the effectiveness of topiramate to treat pain caused by lumbar radiculopathy, or sciatica. Sciatica results from damage to the lumbar nerve roots, typically causing back pain and sharp, shooting pain down one…
- Trial name
- NCT00011804
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Low Back Pain
The Effect Of Low Back Pain on Paraspinal Muscles
Low back pain is frequently seen in the adolescent age group, with a prevalence approaching that of the adult age group. The most common type is non-specific, self-limiting low back pain.
- Trial name
- NCT04555356
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Adolescent Idiopathic Scoliosis (AIS), Back Pain
Impact of Curve Magnitude on Pain and Body Image in Patients With Adolescents Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity characterized by lateral curvature and rotation of the spine.
- Conditions
- Adolescent Idiopathic Scoliosis (AIS), Back Pain, Back Pain Lower Back, Body Image
- Trial name
- AIS (NCT07405112)
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Antalya Training and Research Hospital
Low Back Pain, Knee Arthritis Osteoarthritis
How Patient Education Helps Patients With Chronic Musculoskeletal Disorders Stick to Home Exercise for Pain Relief.
The study aims to evaluate the effectiveness of a structured patient education program in enhancing adherence to prescribed home exercise regimens in individuals with chronic low back pain, knee osteoarthritis, and shoulder pain.
- Conditions
- Low Back Pain, Knee Arthritis Osteoarthritis, Shoulder Disease, Shoulder and Upper Arm Injury
- Trial name
- NCT07764354
- Testing
- Educational with musculoskeletal condition, Standard physical therapy program
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Bladder Cancer, Urethral Cancer
Short-Term Low-Dose Interferon Alfa in Treating Patients With Cancer of the Urothelium
RATIONALE: Interferon alfa may interfere with the growth of tumor cells and slow the growth of urothelial cancer. PURPOSE: This randomized phase I trial is studying how well low-dose interferon alfa works in treating patients…
- Trial name
- NCT00082719
- Testing
- Recombinant Interferon Alfa
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Low Back Pain
Virtual Reality Therapy for Chronic Low Back Pain
This study will test the efficacy of an evidence-based virtual reality (VR) therapy program as a non-pharmacological supplement for the management of chronic lower back pain.
- Trial name
- NCT04409353
- Testing
- Distraction-Based VR, Skills-Based VR, Activity Tracker
- Where
- United States
- Volunteers
- 413 people
- Sponsor
- Cedars-Sinai Medical Center
Lumbago, Anxiety
Assessment of the Effectiveness of a Program of Preparation to Pregnancy and Delivery
Introduction: randomized studies on programs implemented during pre-natal care that offer information and physical activities preparing pregnant women for delivery are scarce in the scientific literature.
- Trial name
- NCT01155804
- Testing
- preparation of the delivery
- Where
- Brazil
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Center for Research on Reproductive Health of Campinas
Quality of Sleep, Subacute or Chronic Low Back Pain
Association Between Low Back Pain and Quality of Sleep
A prospective study to assess the association between the change in quality of sleep and the change in intensity of pain in Spanish patients seen for subacute or chronic low back pain.
- Conditions
- Quality of Sleep, Subacute or Chronic Low Back Pain, Disability, Catastrophizing
- Trial name
- NCT00906152
- Where
- 2 sites in Spain
- Volunteers
- 437 people
- Sponsor
- Kovacs Foundation
Low Back Pain, Spondylosis
Back in the Game: An Immediate Functional Progression Program in Athletes With a Spondylolysis.
Half of all adolescents report experiencing low back pain (LBP), and adolescents who are active in sport report an even higher rate.
- Trial name
- NCT03237104
- Testing
- Immediate PT
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Nationwide Children's Hospital
Lumbar Disc Herniation
Efficacy of Navigable Percutaneous Plasma Disc Decompression Device (L'DISQ) in Patients With Severe Lumbar Disc Herniation
This study aims to assess the clinical outcome of percutaneous disc decompression using the L'DISQ in patients with severe lumbar disc herniation (LDH).
- Trial name
- L'DISQ (NCT05231759)
- Testing
- L'DISQ
- Volunteers
- 30 people
- Sponsor
- Korea University Anam Hospital
Lower Back Pain, Pelvic Pain
Musculoskeletal and Obstetric Management Study
The investigators propose such a trial to compare a Musculoskeletal and Obstetric Management (MOM) program to standard obstetric care alone for lower back pain/pelvic pain (LBP/PP) during and after pregnancy.
- Conditions
- Lower Back Pain, Pelvic Pain, Musculoskeletal Pain
- Trial name
- MOMS (NCT00905112)
- Testing
- Manual Therapy, Standard OB Care
- Where
- 3 sites in United States
- Volunteers
- 160 people
- Sponsor
- Logan College of Chiropractic
Back Pain, Low Back Pain
Neck and Low Back Pain in Physical Therapy Students at The University of the West Indies, Mona, Jamaica
The purpose of this study is to determine the prevalence of neck and low back pain among physical therapy students enrolled at The University of the West Indies, Mona.
- Conditions
- Back Pain, Low Back Pain, Musculoskeletal Pain, Spine Health
- Trial name
- NCT07177001
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Low Back Pain
Pain Experience in Individuals With Chronic Low Back Pain
Low back pain is a very common musculoskeletal condition that affects many people each year regardless of age, gender, and ethnicity.
- Trial name
- NCT03972332
- Testing
- Quantitative Sensory Testing
- Where
- United Kingdom
- Volunteers
- 97 people
- Sponsor
- University of Nottingham
Back Pain, Low Back Pain
Low Back and Neck Pain in Nursing Students at The University of The West Indies
The purpose of this study is to identify the prevalence of neck and low back pain in nursing students enrolled at the University of the West Indies, Mona; to assess their knowledge, attitude and practice of good spine health and…
- Conditions
- Back Pain, Low Back Pain, Musculoskeletal Pain, Neck Pain
- Trial name
- NCT07167888
- Testing
- Clinical Control Group (Group A), Spine Exercise Program (Group B)
- Where
- Jamaica
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The University of The West Indies
Low Back Pain, Radiculopathy
Comparison Between Endoscopic Epidural Neuroplasty and Percutaneous Epidural Neuroplasty in Low Back and Radicular Pain
PEN(percutaneous epidural neuroplasty) can be performed percutaneously, may be manipulated to mechanically break up adhesions by catheter, while various agents, such as anesthetics, corticosteroids, hyaluronidase, and hypertonic…
- Trial name
- NCT05533723
- Testing
- Endoscopic epidural neuroplasty, Percutaneous epidural neuroplasty (PEN)
- Where
- South Korea
- Volunteers
- 107 people
- Sponsor
- Ajou University School of Medicine