Clinical trials: Low Bone Density
Postmenopausal Osteoporosis, Postmenopause
Frequency of Hyperparathyroidism in Postmenopausal Osteoporosis and Its Treatment
Recently, an increase in the prevalence of hyperparathyroidism and hypovitaminosis D in postmenopause women has been occurring in Mexico and the world.
- Conditions
- Postmenopausal Osteoporosis, Postmenopause, Hyperparathyroidism, Secondary, Hypovitaminosis D
- Trial name
- NCT05347082
- Testing
- Cholecalciferol
- Where
- Mexico
- Volunteers
- 47 people
- Sponsor
- Hospital Regional 1o de Octubre
Bone Density, Energy Availability
Low Energy Availability, Menstrual Irregularity, and Low Bone Mass
This study examines the role of energy availability on menstrual function and bone mass in female adolescent endurance athletes.
- Trial name
- NCT01059968
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Bone Disease, Metabolic
Elucidating the Minimal Effective Dose of Prunes for Bone Health in Postmenopausal Women
The objective of this study is to examine if calcium and vitamin D supplements and/or prune can prevent bone loss in postmenopausal women.
- Trial name
- NCT06184646
- Testing
- Prune
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- San Diego State University
Vitamin D Deficiency, Osteopenia of Prematurity
The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants.
The aim of this study will be to assess the effectiveness of monitored vit D supplementation in a population of preterm infants and to identify whether the proper vit D supplementation in preterm infants can reduce the incidence…
- Conditions
- Vitamin D Deficiency, Osteopenia of Prematurity, Nephrolithiasis, Metabolic Bone Disease
- Trial name
- HIDVID (NCT06199102)
- Testing
- cholecalciferol/ Devikap
- Where
- Poland
- Volunteers
- 130 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Osteopenia, Osteoporosis
Periprosthetic Plate Over Humeral Nail
use of plate over humeral nail in deformity correction of femur in adult osteoporotic bone
- Trial name
- osteoporosis (NCT06812195)
- Testing
- Plate and nail
- Volunteers
- 3 people
- Sponsor
- Assiut University
Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population
Advancing Early Bone Health: New Frontiers for Osteoporosis Prevention
All factors that influence the peak bone mass achieved at skeletal maturity are important in determining an individual's risk of developing osteoporosis later in life.
- Conditions
- Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population, Healthy Neonatal Population
- Trial name
- REMS-BONE (NCT06750523)
- Testing
- Cord blood sampling, urine sampling, Life style questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Parma
Periodontal Bone Loss
Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients
The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth.
- Trial name
- NCT02972788
- Testing
- Enamel Matrix Proteins Derivative, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Dental Implants, Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability
Periosteal Sutures Versus Titanium Tacks for Guided Bone Re-generation in the Aesthetic Zone: a Pilot Randomized Controlled Trial
This randomized controlled clinical study, titled "Periosteal sutures for fixation of composite bone substitutes in guided bone regeneration: a randomized controlled clinical study," is being conducted at the Dental Unit of…
- Conditions
- Dental Implants, Dental Implants , Osseointegration , Marginal Bone Loss , Implant Stability, Maxillary Alveolar Reconstruction
- Trial name
- NCT07330232
- Testing
- Periosteal mattress sutures for graft/membrane stabilization in guided bone regeneration Titanium tacks for graft/membrane stabilization in guided bone regeneration
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
HIV Infections, HIV-Associated Lipodystrophy Syndrome
A Study of Physical and Metabolic Abnormalities in HIV Infected and Uninfected Children and Youth
The purpose of this study is to assess the prevalence of metabolic and physical abnormalities in HIV infected (via mother-to-child transmission) and uninfected children and youth.
- Conditions
- HIV Infections, HIV-Associated Lipodystrophy Syndrome, HIV Lipodystrophy Syndrome, Lipodystrophy
- Trial name
- NCT00069004
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Spinal Cord Injury, Osteoporosis
Early Intervention to Reduce Bone Loss After Spinal Cord Injury
After a complete spinal cord injury (SCI), the patient becomes wheelchair-dependent, and the associated lack of weight-bearing and inactivity of paralysed muscles can lead to extensive bone loss in the long bones of the legs.
- Trial name
- NCT02334410
- Testing
- Whole body vibration (WBV)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Strathclyde
Osteopenia or Osteoporosis
The Effect of Effervescent Alendronate on Bone Turnover
64 postmenopausal women are randomized to treatment with either effervescent and buffered alendronate or conventional alendronate -both 70mg weekly for 16 weeks to see if bone turnover is suppressed to the same extent as in the…
- Trial name
- NCT05325515
- Testing
- Conventional alendronate, Effervescent and buffered alendronate
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Aarhus University Hospital
Implant Placement in Maxillary Esthetic Zone
Evaluation of Marginal Bone Loss After Immediate Implant Placement in Maxillary Esthetic Zone With Nanobone Versus Xenograft
Immediate implant placement has a success rate from 94-100 % . After tooth extraction there is a loss in the horizontal and vertical dimension by about 3-6 mm and 1-2 mm respectively and alveolar crest resorption of about 44%…
- Trial name
- NCT03536260
- Testing
- Implant with NanoBone graft, Implant with Xenograft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Osteopenia, Osteoporosis
The Effects of Bovine Colostrum in Bone Metabolism in Humans
Osteoporosis constitutes a major public health concern. For instance, in European Union 1 in 3 women and at least 1 in 6 men will suffer an osteoporotic fracture during their lifespan.
- Trial name
- NCT04040010
- Testing
- Colostrum supplementation for bone loss
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Osteoporosis
Phase III Randomized Study of the Effect of Postmenopausal Estrogen Replacement Therapy on Alveolar Bone Loss
OBJECTIVES: I. Quantify periodontal alveolar bone loss rates in postmenopausal women. II. Evaluate the effects of estrogen on alveolar bone loss rates in these patients. III.
- Trial name
- NCT00004650
- Testing
- conjugated estrogens, Medroxyprogesterone
- Volunteers
- 150 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Crohn's Disease, Osteopenia
Zoledronate for Osteopenia in Pediatric Crohn's
Background: Up to 30% of children and adolescents with Crohn's disease have decreased bone strength, or decrease bone density, called osteopenia.
- Conditions
- Crohn's Disease, Osteopenia, Osteoporosis
- Trial name
- NCT00798473
- Testing
- zoledronic acid, IV saline infusion
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Bone Loss, Breast Cancer
Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.
Post-menopausal breast cancer patients will receive letrozole 2.5 mg daily for the treatment of breast cancer and will be randomized to a treatment group to receive either upfront zoledronic acid 4 mg IV 15-minute infusion every…
- Trial name
- NCT00171340
- Testing
- Zoledronic acid, Letrozole
- Where
- 106 sites in Argentina, Australia and 26 more
- Volunteers
- 1,065 people
- Sponsor
- Novartis Pharmaceuticals
Bone Loss, Age-Related
Bone Fragility Study in Pediatric Population With Risk Factors
Low bone mass and osteoporosis are underdiagnosed in childhood in our environment and its prevalence is unknown. In most cases they are secondary to chronic diseases that conduct to a poor bone health condition and thereby a risk…
- Trial name
- NCT02751008
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Anterior Shoulder Dislocation, Shoulder Dislocation Closed Traumatic
Shoulder Dislocation: Assessment of Lesions, Trajectories and Outcomes (SALTO)
The goal of this prospective observational cohort study is to provide epidemiological and prognostic data from a defined urban population and to improve understanding of risk factors and long-term outcomes following first-time…
- Conditions
- Anterior Shoulder Dislocation, Shoulder Dislocation Closed Traumatic, First Time Shoulder Dislocation, Shoulder Instability
- Trial name
- SALTO (NCT07486440)
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- Oslo University Hospital
Osteoporosis, Postmenopausal
Hesperidin and Bone Health in Postmenopausal Women
The primary objective of this clinical trial is to test hesperidin with and without CALCILOCK® for bone resorption suppressing effect in postmenopausal women.
- Trial name
- Hesperidin (NCT01881204)
- Testing
- Hesperidin and Calcilock, Hesperidin, Control
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Purdue University
Osteopenia of Prematurity
Low and High Doses of Prophylactic Vitamin D in Prevention of Osteopenia of Prematurity
In this study the effects of low and high doses of prophylactic vitamin D on biochemical and radiological manifestations of osetopenia of prematurity will be tested.
- Trial name
- NCT04768439
- Testing
- Low Dose Vitamin D, High Dose Vitamin D
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University