Clinical trials: Low Level Laser Therapy
Dental Caries
Effect of Photodynamic Therapy With Low-level Laser on Infected Dentin in Primary Teeth: A Controlled Clinical Trial
The aim of the proposed study is to assess the clinical effect of photodynamic therapy (PDT) on dentin with carious lesions in primary teeth.
- Trial name
- NCT02734420
- Testing
- PapacarieMBlue and PDT, Toluidine Blue O and PDT, Laser
- Where
- Brazil
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Malocclusion Class II
Effect of Low Level Laser Therapy on the Temporomandibular Joint During Treatment of Skeletal Class II Malocclusion
to evaluate effect of low-level laser therapy (LLLT) on mandibular condylar volume and position after treatment of Class II malocclusion with Twin Block (TB) functional therapy via cone beam computed tomography (CBCT).
- Trial name
- NCT04376190
- Testing
- low level laser therapy
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- mahmoud abdelhameed mohamed
Hypomineralization Molar Incisor
Laser Therapy and Flouride Therapy in Desensibilization Hypomineralized Teeth
To investigate the efficacy of laser therapy associated with fluorotherapy in the desensibitization of hypomineralized teeth in children 8 to 12 years of age. A randomized blinded clinical trial will be conducted.
- Trial name
- LTAFTIDHT (NCT03823170)
- Testing
- Laser therapy, Fluorotherapy, Laser therapy and Fluorotherapy
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universidade Ceuma
Oral Mucositis, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy
Study of a Copaiba-Based Mouthwash Combined With Low-Level Laser Therapy in the Prevention of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation
Oral mucositis (OM) one of the most significant acute toxicity of Hematopoietic Stem Cell Transplantation (HSCT). There is already scientific evidence suporting OM the use of: low-level laser therapy (LLLT), cryotherapy (in…
- Conditions
- Oral Mucositis, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Oral Mucositis Due to Chemotherapy, Oral Mucositis in Patients Undergoing HSCT
- Trial name
- NCT07810530
- Testing
- Copaíba
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Proiriftrative Diabetic Retinopathy
Comparison of Two Laser Therapy Methods for PDR
Proliferative diabetic retinopathy (PDR) is treated with conventional pan retinal photocoagulation (PRP) which can improve the visual prognosis in this complication significantly.
- Trial name
- PDR (NCT01232179)
- Testing
- conventional prp, targeted prp
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Root Resorption of Maxillary Incisors
Effect of Low Level Laser Therapy on Root Resorption During Orthodontic Intrusion of Maxillary Incisors
The present study will be directed to evaluate the effect of low-level laser therapy on root resorption during orthodontic intrusion of upper incisors.
- Trial name
- NCT05707416
- Testing
- gallium aluminum arsenide (Ga-Al-As) semiconductor diode laser (SMARTTM PRO, LASOTRONIX, Poland), group B
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Symptomatic Irreversible Pulpitis, Symptomatic Irreversible Pulpitis (SIP)
Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy
This study evaluates treatment options for children and young adults with severe toothache in a permanent molar caused by symptomatic irreversible pulpitis.
- Trial name
- NCT07290049
- Testing
- Calcium Silicate Cement, Er,Cr:YSGG Laser
- Where
- United Arab Emirates
- Volunteers
- 46 people
- Sponsor
- University of Fujairah
Photodynamic Therapy& Low Level Laser in Management of COVID 19
Photodynamic Therapy for the Treatment of COVID-19
Until now there is no vaccine or reliable treatment for the COVID-19 pandemic. The fundamental mechanisms of non-invasive low-level laser in photobiomodulation (PBM) and photodynamic therapy is to stimulate the mitochondrial…
- Trial name
- NCT04416113
- Testing
- photobiomodulation and photodynamic therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Dental Malocclusion
Laser in Orthodontic Leveling and Alignment
to evaluate the outcome of LLLT regarding leveling and alignment of the mandibular anterior segment.
- Trial name
- NCT04376164
- Testing
- low level laser therapy
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tharwat osman Mohi Eldeen Elshehawy
Diabetic Mellitus, Laser
Helium-Neon Laser Therapy Versus Infrared Laser Therapy in Treating Patients With Diabetic Foot Ulcer
Background: Diabetic patients are frequently showed with foot ulceration as a common complication which increases to 20% in admission.
- Trial name
- NCT03338517
- Testing
- Helium Neon Laser
- Volunteers
- 65 people
- Sponsor
- Ahlia University
Inferior Alveolar Nerve Injuries
Does Low-level Laser Therapy Protocol Affect the Efficacy of Treatment of Inferior Alveolar Nerve Injury After Maxillofacial Surgery
Dear Patient, Dear Parent / Guardian; This consent form has been prepared to enlighten you about the nature of the diagnosis and treatment methods that have been explained to you/patient and will be applied, the expected benefits…
- Trial name
- NCT06893497
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Karadeniz Technical University
Oral Mucositis Due to Chemotherapy, Hematolymphoid Malignancies
Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid Malignancies
Chemotherapy induced oral mucositis is a common and debilitating complication in pediatric patients receiving chemotherapy for hematolymphoid malignancies.
- Trial name
- BEAM (NCT07605234)
- Testing
- Photobiomodulation Therapy
- Volunteers
- 46 people
- Sponsor
- Tata Memorial Hospital
Dentofacial Deformity
Lower Laser Therapy in Orthognathics Surgery
This study will examine the use of lower laser therapy to reduce edema and pain in orthognathics surgery.
- Trial name
- NCT01530100
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Cystocele, Vaginal Vault Prolapse
Laser Therapy in Managing Vaginal Prolapse
Efficacy of laser therapy in postmenopausal women with symptomatic prolapse stage >1. Assessment tools will include prolapse stage quantification system (POP-Q) and validated condition related questionnaires.
- Conditions
- Cystocele, Vaginal Vault Prolapse, Rectocele, Enterocele
- Trial name
- NCT03714607
- Testing
- Erbium Yttrium Aluminum Garnet (Er:YAG) laser
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Muscle Tear
Effects of High Intensity Laser Therapy in Muscle Injuries
Muscle injuries are frequent traumatic events in daily life, particularly during sports. In sports, their incidence varies from 10% to 55% of total injuries.
- Trial name
- THEALinMJ (NCT06812611)
- Testing
- High Energy Laser Group, Exercise
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Low Level Laser Therapy, Canine Retraction
Three-dimensional Assessment of the Bone Changes Accompanying Laser-assisted Orthodontic Tooth Movement
Aim of the present study is to evaluate the effect of low-level laser therapy on bone quality and quantity with orthodontic tooth movement.
- Conditions
- Low Level Laser Therapy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- NCT05811728
- Testing
- Low level laser therapy, without beam emission
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Anterior Knee Pain, Photobiomodulation (PBM)
Photobiomodultion in Anterior Knee Pain
The goal of this clinical trial is to assess the augmented recovery in the adolescent females with patellar tendinopathy using Phot- Biomodulation
- Conditions
- Anterior Knee Pain, Photobiomodulation (PBM), Laser Therapy
- Trial name
- PBM (NCT07865325)
- Testing
- Photobiomodultion with Laser scanning, patellar mobilization with exercise therapy
- Where
- Jordan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- New Ismailia National University
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Autistic Disorder
An Evaluation of Low Level Laser Light Therapy for Autistic Disorder
The purpose of this study is to determine whether the Erchonia HLS Laser is effective in the treatment of irritability associated with autistic disorder in children and adolescents aged five (5) to seventeen (17) years.
- Trial name
- NCT03379662
- Testing
- Erchonia HLS Laser
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Erchonia Corporation