Clinical trials: Lower Extremity Fracture
Femur Fracture, Childhood
Study of the Geometry of the Immature Human Femur Before the Age of 3 Years From Data Measured on CT Scan
Childhood fractures are the second most common presentation of abuse. The target population for screening for these injuries is children under the age of three who are unable to express themselves about the circumstances of the…
- Trial name
- GFI (NCT05620394)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Tibial Fractures, Intra-Articular Fractures
Management of Traumatic Bone Defects in Tibial Plateau Fractures With Antibiotic-Impregnated Biodegradable Calcium Sulfate Beads: A Prospective Clinical Trial
This is a prospective clinical trial of tibial plateau fractures treated with internal fixation and a calcium sulfate graft which can be mixed with antibiotics and molded into various bead sizes for implantation into bone…
- Conditions
- Tibial Fractures, Intra-Articular Fractures, Fracture Fixation, Internal
- Trial name
- NCT02456194
- Testing
- Calcium Sulfate + Antibiotics + Internal Fixation
- Where
- 5 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Ross Leighton
Fracture
To Investigate the Effect of Early Community-care Program on Fracture Hip Patient
The early community-care program is well-known rehabiliation for the fracture hip patient. For the discharged fracture hip patient from hospital, it is worth to investigate the effect of early mobilization program to improve…
- Trial name
- NCT01537523
- Testing
- community-care program
- Volunteers
- 60 people
- Sponsor
- Hong Kong Healthcare Volunteer Organization
Deformity, Defect, Congenital
Observational Study on JuniOrtho Plating System for Deformities and Fractures Treatment in Lower Limb
Orthofix Srl put the JPS on the European market (2019) by the mean of a pre-market clinical evaluation made under the Medical Device Directive (MDD) requirements that were based on the analysis of the scientific literature of…
- Conditions
- Deformity, Defect, Congenital, Trauma
- Trial name
- JPS (NCT05245617)
- Testing
- JuniOrtho™ Plating System™
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Orthofix s.r.l.
Alzheimers Disease, Inflammation
Alzheimers Disease and Neuromarkers in Patients With Acute Hip Fractures
The investigators explore the presence of AD factors beta-amyloid and tau in CSF and plasma to verify AD diagnosis in patients with acute hip fracture. Clinical dementia test is performed prior to operation.
- Conditions
- Alzheimers Disease, Inflammation, Hip Fracture
- Trial name
- ADhipfract (NCT02409082)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Sahlgrenska University Hospital
Proximal Femur Fractures
Our Experience in the Management of Therapeutic Failures of Fractures of the Proximal End of the Femur (About 35 Cases)
Osteosyntheses employed in treating fractures at the upper end of the femur play a critical role in facilitating a swift recovery by minimizing immobilization periods and enabling early rehabilitation of the affected joints…
- Trial name
- NCT06360835
- Testing
- total hip arthroplasty
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- Ibn Jazzar Hospital
Osteomyelitis Tibia, Surgical Site Infection
Acute Posttraumatic Osteomyelitis in Patients With High-energy Tibial Fractures and Biomarkers
The present trial was aimed to identify which biomarkers could be associated in perioperative period after surgical treatment of tibial fracture to the development of POM.
- Trial name
- POMTIBIAL (NCT03459261)
- Testing
- blood sample on admission (ADD), first postoperative day (POD1) and fourth postoperative day (POD4)
- Volunteers
- 86 people
- Sponsor
- University Medical Centre Ljubljana
Hip Fractures, Gait Disorders in Old Age
Clinical Study of the Effects of a SWalker II and VR for Hip Fracture Rehabilitation in the Elderly
This project is structured in two distinct phases. The first phase deals with the recovery of the hip fracture in the acute phase up to ambulation, and the second is understood as the continuation of functional improvement of…
- Trial name
- SWalker-VR (NCT06025981)
- Testing
- Preliminary Phase, Phase I - Early gait rehabilitation, Phase II - Maintenance gait function ( with VR)
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Werium Assistive Solutions
Femoral Fracture, Children
Modification of ESIN-osteosynthesis in a Femoral Fracture Model and Its Transmission to Clinical Practice
Elastic stable intramedullary nailing (ESIN) is the standard treatment for displaced diaphyseal femoral fractures in children. However, some literature report high complication rates (10-50%) in complex fractures.
- Trial name
- ESIN (NCT01673048)
- Testing
- 3-Nail-ESIN in femoral shaft fractures
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Luebeck
Neck of Femur Fracture
PENG Versus Femoral Nerve Block in Neck of Femur Fracture
Neck of femur (NOF) fracture is a common presentation to the emergency department, particularly in our older population. NOF fracture is associated with a high social and economic cost with significant effects on patients'…
- Trial name
- NCT05002725
- Testing
- Lidocain
- Where
- Ireland
- Volunteers
- 64 people
- Sponsor
- University College Cork
Tibial Fractures
Management of Closed Diaphyseal Displaced Leg Fractures in Children and Adolescents
Most displaced tibial shaft fractures in pediatric patients have traditionally been treated after reduction by cast immobilization with good long-term results.
- Trial name
- FFD (NCT06503718)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Strasbourg, France
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Tibial Fractures
ACTiF- Assessment of Closed Tibial Fractures
The purpose of this study is to find out the good and bad effects of an investigational drug called CP-533,536 in patients with closed fracture of the tibial shaft undergoing internal fixation using reamed inter-locked IM nailing…
- Trial name
- NCT00533377
- Testing
- CP-533, 536, Standard of Care, CP-533,536
- Where
- 56 sites in United States, Australia and 9 more
- Volunteers
- 276 people
- Sponsor
- Pfizer
Procedural Sedation
Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique
Abstract Background: Ketamine has been introduced as one of the most common drugs, administered to sedate children for different painful procedures in the emergency department (ED) but administration in higher dosage causes some…
- Trial name
- NCT03499886
- Testing
- Ketamine Hydrochloride 50Mg/1mL Solution for Injection, Ketamine Hcl 50Mg/Ml Inj
- Where
- 2 sites in Iran
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Femur Fracture
Pediatric Locking Nail for the Treatment of Femoral Fractures in Children
The purpose of this multi-center prospective clinical outcomes study is to determine validity and safety of the pediatric locking nail for femoral fracture management in children with open physes.
- Trial name
- PLN (NCT00725894)
- Testing
- Pediatric Locking Nail
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Zimmer Biomet
Hip Fractures
Improving Quality of Care for Hip-Fracture Patients: Studies on Fast-track Surgery
The aims of the studies are to examine the impact of delayed time to surgery for hip-fracture patients with regard to in-hospital complication rate and one-year mortality and to evaluate two different fast-track systems for…
- Trial name
- Q-HIP (NCT01487772)
- Where
- Sweden
- Volunteers
- 1,307 people
- Sponsor
- Danderyd Hospital
Proximal Femur Fractures
Development and Validation of Intraoperative Image-quality Criteria
An expert panel of surgeons agreed that there is not any established, standardized approach to the teaching of intraoperative imaging and that there may be practice gaps in decision making and the use of imaging among trauma…
- Trial name
- NCT01660490
- Testing
- ORIF
- Where
- 3 sites in United States, Austria and 1 more
- Volunteers
- 200 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Femoral Fractures, Tibial Fractures
Depuy Synthes Lower Extremity Shaft Nail Registry
The purpose of this post-market registry is to monitor the clinical safety and performance (union rates and time to union) of two DePuy Synthes lower extremity shaft nails: RFN-Advanced Retrograde Femoral Nailing System (RFNA)…
- Trial name
- NCT05272631
- Testing
- Retrograde Femoral Nail Advanced, Tibial Nail Advanced
- Where
- 8 sites in United States
- Volunteers
- 241 people
- Sponsor
- DePuy Synthes Products, Inc.
Hip Surgery, Hip Arthroplasty
The Quadro-Iliac Plane (QIP) Block in Hip Surgery
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including…
- Trial name
- QIP in hip (NCT07591311)
- Testing
- Fascia iliaca block (FIB)
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- San Giovanni di Dio Hospital
Hip Fractures, Undisplaced Intracapsular Hip Fracture
Fixation Versus Arthroplasty for Undisplaced Intracapsular Fractures
In England each year over 70,000 people fracture their hip. Most of these patients are elderly females with the fracture occurring after a simple trip or stumble.
- Trial name
- NCT02996383
- Testing
- Internal fixation, Cemented Hemiarthroplasty
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Peterborough and Stamford Hospitals NHS Foundation Trust