Clinical trials: Lower Extremity Fractures
Osteoporosis
GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP)
The study is designed as a retrospective, multicenter study for subjects previously treated with the AGN1 LOEP Kit in the proximal femur as part of standard hospital practice. This will be a non-randomized and non-blinded study.
- Trial name
- NCT07594639
- Testing
- AGN1 LOEP
- Where
- Belgium
- Volunteers
- 305 people
- Sponsor
- AgNovos Healthcare, LLC
Hip Fracture
Treatment of Muscle Injury Following Arthroplasty for Hip Fracture (HF)
The objectives of this study are to assess the efficacy, safety, and tolerability of PLX-PAD intramuscular administration for the treatment of muscle injury following arthroplasty for HF.
- Trial name
- NCT03451916
- Testing
- PLX-PAD
- Where
- 17 sites in United States, Bulgaria and 3 more
- Volunteers
- 240 people
- Sponsor
- Pluristem Ltd.
Hypertension, Dementia
BedMed-Frail: Does the Potential Benefit of Bedtime Antihypertensive Prescribing Extend to Frail Populations?
High blood pressure (present in 1 of 5 Canadian adults) increases the risk of heart attack and stroke. Blood pressure lowering pills reduce this risk - but perhaps not optimally.
- Trial name
- NCT04054648
- Testing
- Bedtime administration of the participant's pre-existing antihypertensive medications
- Where
- Canada
- Volunteers
- 776 people
- Sponsor
- University of Alberta
Hip Fracture of Intertrochanteric Type
Postoperative Analgesia With Local Infiltration After Hip Fracture Of Intertrochanteric Type
Reducing pain is an essential factor for early mobilization after osteosynthesis of intertrochanteric fractures. Systemic opioids have side effects that might obstruct mobilization and induce delirium and nausea.
- Trial name
- NCT01119209
- Testing
- Ropivacaine, Saline
- Where
- Denmark
- Volunteers
- 74 people
- Sponsor
- Odense University Hospital
Metatarsal Stress Fracture, Stress Fracture of Tibia
Photobiomodulation Therapy for the Treatment of Lower Extremity Stress Fractures in a Military Training Setting
The goal of this clinical trial is to compare photobiomodulation therapy (PBMT) in addition to standard of care in the treatment of tibial and metatarsal bone stress injuries in a military training setting.
- Trial name
- PM12 (NCT05843864)
- Testing
- Photobiomodulation Therapy with Standard Physical Therapy
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Brooke Army Medical Center
Tibial Fractures
Results of Cross-leg Free Vascularized Fibular Graft
This study aims to evaluate the new technique of cross-leg vascularized fibular graft for reconstruction of post-traumatic long tibial bone defects in terms of restoring normal anatomy and function of the traumatized limb in a…
- Trial name
- NCT06491316
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Assiut University
Ankle Injuries, Ankle Fractures
Deltoid Ligament Arthroscopic Repair in Ankle Fractures: Case Series
To demonstrate the functional results of patients with ankle fractures operated with arthroscopic deltoid repair.
- Conditions
- Ankle Injuries, Ankle Fractures, Deltoid Ligament; Sprain (Strain) (Ankle), Ligament Rupture
- Trial name
- NCT04473638
- Testing
- Arthroscopic Deltoid Repair
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Federal University of São Paulo
Knee Pain
Anterior Knee Pain After Tibial Nailing
Anterior knee pain (AKP) is a common complication following intramedullary (IM) nailing of a tibial shaft fracture. The purpose of this prospective study was to determine if there is an association between AKP and nail position.
- Trial name
- NCT01106963
- Testing
- Tibial intramedullary nailing
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Patella, Joint Instability
Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
About six months after patella stabilizing surgery postoperative restrictions are commonly lifted and patients may consider whether a return to activity/sports is feasible.
- Conditions
- Patella, Joint Instability, Patellofemoral Joint Dislocation
- Trial name
- NCT05119088
- Testing
- Return to Sport testbattery
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Femur Fracture
Titanium Elastic Nails in the Treatment of Pediatric Femur Fractures
Titanium elastic nails in the pediatric femoral fractures: A prospective randomized clinical trial of eliminating nail protrusion to decrease soft tissue complications
- Trial name
- NCT00175656
- Testing
- Elimination of titanium elastic nail prominence at the insertion site and leaving the nails in situ
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Proximal Femoral Fracture
Proximal Femoral Fractures - Patient Population, Risk Factors, Surgical Performance and Outcome
Proximal femoral fractures are a typical pathology in elderly patients after a low-energy trauma. This study analyses preexisting risk factors for proximal femoral fractures as well as for failing to reach the previous functional…
- Trial name
- ProFi (NCT03768622)
- Testing
- surgery for pertrochanteric femoral fracture, surgery for femoral neck fracture
- Where
- Switzerland
- Volunteers
- 2,906 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Compartment Syndrome, Tibia Fracture
Biomarkers in the Diagnosis of Acute Compartment Syndrome
This prospective multinational, multicentre cohort study aims to investigate the hypothesis that biomarkers of muscle cell damage can predict acute compartment syndrome in patients with tibial fractures.
- Trial name
- BioFACTS (NCT04674592)
- Testing
- Blood samples and biopsies
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- University Hospital, Linkoeping
Pelvic Fracture
The Role of Intraoperative Navigation-assisted Channel Screw Technique in the Treatment of Pelvic Fractures
This was a multicenter, prospective, randomized, controlled study. Patients with pelvic fractures (Tile B and c) were recruited from the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an Red Society Hospital and Xi'an…
- Trial name
- INCST (NCT05448911)
- Testing
- Intraoperative navigation combined with Catheter screw technique, Open reduction and internal fixation with steel plate
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Proximal Femur Fractures
Our Experience in the Management of Therapeutic Failures of Fractures of the Proximal End of the Femur (About 35 Cases)
Osteosyntheses employed in treating fractures at the upper end of the femur play a critical role in facilitating a swift recovery by minimizing immobilization periods and enabling early rehabilitation of the affected joints…
- Trial name
- NCT06360835
- Testing
- total hip arthroplasty
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- Ibn Jazzar Hospital
Hip Fractures, Sarcopenia
Feasibility of High Density Sit-to-stand Functional Resistance Training in Patients With Hip Fracture
The objective of this study is to examine if functional high-density, high-volume chair rise training is feasible for increasing lower extremity strength without causing excessive hip pain during execution in patients with hip…
- Conditions
- Hip Fractures, Sarcopenia, Fall Injury
- Trial name
- NCT05840315
- Testing
- Basic intervention and nutritional intervention, Sit-to-stand, Leg press
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Horsholm Municipality
Hip Fracture
Single Shot Fascia Iliaca Block vs Femoral Nerve Block for Analgesia for Surgical Fixation of Hip Fractures
Hip fractures are common in our elderly population and is associated with pain before and after surgery. The current pain management for patients who have undergone surgery for hip fractures include a combination of oral…
- Trial name
- NCT02330302
- Testing
- Ropivacaine
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Changi General Hospital
Tibial Fractures
Compartmental Overpressures Associated to Reamed Intramedullary Nails
The purpose of this study is to determine the effect of reamed intramedullary nails in tibial shaft fractures (as a standard treatment), in raising intracompartmental pressures and therefore determine if they are a risk factor…
- Trial name
- NCT00842101
- Testing
- Quick Pressure Monitor
- Where
- Andorra
- Volunteers
- 80 people
- Sponsor
- University of Andorra
Femoral Neck Fractures
Open vs Closed Reduction in Femoral Neck Fractures Using Anterolateral vs Direct Lateral Approach
Outcomes of open vs closed reduction if emoral neck fractures
- Trial name
- FNFs (NCT07299370)
- Testing
- Closed reduction of femoral neck fractures, Open reduction of femoral neck fractures
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Samer youssef mansour meglaa
Hip Fractures
Improving Quality of Care for Hip-Fracture Patients: Studies on Fast-track Surgery
The aims of the studies are to examine the impact of delayed time to surgery for hip-fracture patients with regard to in-hospital complication rate and one-year mortality and to evaluate two different fast-track systems for…
- Trial name
- Q-HIP (NCT01487772)
- Where
- Sweden
- Volunteers
- 1,307 people
- Sponsor
- Danderyd Hospital
Femoral Neck Fractures
Pediatric Hip Plate Versus Cannulated Screw in Pediatric Femoral Neck Fracture
The purpose of this study is to compare the early postoperative radiologic and clinical outcomes of pediatric hip plate and cannulated screw fixation in pediatric femoral neck fracture (Delbet type II and Delbet type III).
- Trial name
- PFNF (NCT02803983)
- Testing
- Pediatric hip plate, Cannulated screw
- Volunteers
- 30 people
- Sponsor
- The Fuzhou No 2 Hospital