Clinical trials: Lumbar
Fever
Ultrasound-Assisted Lumbar Puncture in Children
The aim of this study is to determine if emergency physician performed ultrasound-assisted lumbar puncture improves first-time success rates in a pediatric population.
- Trial name
- NCT03099642
- Testing
- ultrasound-assisted lumbar puncture
- Where
- Canada
- Volunteers
- 166 people
- Sponsor
- St. Justine's Hospital
HIV Infection
The Efavirenz (EFV) Central Nervous System Exposure Sub-study of Encore1
Persistent HIV infection in the central nervous system (CNS) compartment may put subjects at risk of developing HIV-related brain disease.
- Trial name
- ENCORE1-CNS (NCT01451333)
- Testing
- Efavirenz
- Where
- 5 sites in Germany, Thailand and 1 more
- Volunteers
- 32 people
- Sponsor
- Kirby Institute
Lumbar Total Disk Replacement
French Lumbar Total Disk Replacement Observational Study
Primary Objective: To evaluate the rate of re-operation during the first 5 years following the fitting of lumbar total disk replacement at the operated level and / or floors above and / or underlying, whatever the reasons
- Trial name
- PTDL (NCT02381574)
- Where
- 70 sites in France
- Volunteers
- 600 people
- Sponsor
- Medtronic France SAS
Traumatic Lumbar Puncture
The Effect of Bedside Ultrasound Assistance on the Proportion of Successful Infant Spinal Taps
The reported rate of unsuccessful spinal taps in children, especially young infants, is high. Our hypothesis is that ultrasound assistance can improve the success rate of spinal taps.
- Trial name
- NCT02133066
- Testing
- Bedside Ultrasound-Assisted Site Marking, Mindray M7 Ultrasound, Routine lumbar puncture
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Post Operative Pain
Ultrasound-Guided Lumbar Erector Spinae Plane Block Versus Caudal Block for Postoperative Analgesia in Hip and Proximal Femur Surgery in Pediatric Patients
The study will compare Ultrasound-Guided Lumbar Erector Spinae Plane Block and caudal block for Postoperative Analgesia in Hip and Proximal Femur Surgery in pediatric patients
- Trial name
- NCT05157516
- Testing
- erector spinea block, Caudal epidural block
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Multiple MRI Exams, Including, Cardiac
General Investigative MRI Protocol
This study is a feasibility study to evaluate new technology to improve the MRI experience, with coils, sequences and software. Patients from the Principle Investigator's exam schedule are given the opportunity to participate in…
- Conditions
- Multiple MRI Exams, Including, Cardiac, Abdominal, Lumbar
- Trial name
- NCT01598766
- Testing
- 16 Channel SPEEDER Flex Coil
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Toshiba America Medical Systems, Inc.
Back Pain, Sciatica
Predictive Value of the Five-repetition Sit-to-stand Test After Lumbar Spine surgerySTS-3 Study.
Sciatica is a disabling condition that affects many people. This condition has an enormous influence on the social functioning of patients.
- Trial name
- 5R-STS-III (NCT04660656)
- Testing
- 5 repetition sit-to-stand test
- Where
- 2 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- Bergman Clinics
Idiopathic Scoliosis
The Effect of Vertebral Body Tethering on Lumbar Paraspinal Muscle Cross-Section Area in Adolescent Idiopathic Scoliosis
We aimed to compare the paraspinal muscle cross-section area and functional results of anterior vertebral tethering and selective thoracic fusion surgery.
- Trial name
- NCT05347056
- Testing
- Lumbar Spine Magnetic Resonance, Isokinetic trunk flexion-extension trunk muscle strength and endurance test, Lomber Region Range of motion assessment
- Volunteers
- 16 people
- Sponsor
- Istanbul University
Leukemia, Lymphoid Malignancies
Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System
The goal of this clinical research study is to learn about the safety and effectiveness of rituximab given by spinal tap in patients with lymphoid malignancies involving the central nervous system.
- Conditions
- Leukemia, Lymphoid Malignancies, Metastatic Malignant Neoplasm to the Leptomeninges
- Trial name
- NCT01596127
- Testing
- Intrathecal Rituximab
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- M.D. Anderson Cancer Center
Epilepsy
Herpes Virus-6 and Epilepsy
This study will explore whether the human herpes virus-6 is associated with epileptic seizures. The virus may be involved in brain scarring, called mesial temporal sclerosis, which is seen in some epilepsy patients.
- Trial name
- NCT00085683
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lumbar Canal Stenosis
Anterior Discectomy Surgery With Arthrodesis in Degenerative Spinal Canal sténoses. (ICASC)
Single-center retrospective study to characterize changes in the functional capacity of patients (change in Oswestry Desability Index (ODI)) undergoing anterior approach surgery for the management of symptomatic lumbar spinal…
- Trial name
- ICASC (NCT06555887)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Brest
Back Pain, Back Disorder
Clinical Trial of Dvectis Pads in Comparison to no Pad Use in Patients With Chronic Lumbar Spine Pain
1. Introduction 1.1 Description of the Trial The trial was a monocentric, open, randomized, 3-arm clinical trial that took place at the Department of Orthopaedics of the Karviná Miners' Hospital (Karvinská hornická nemocnice…
- Conditions
- Back Pain, Back Disorder, Disease Lumbar Spine
- Trial name
- NCT03947580
- Testing
- Use of the Dvectis Single pad, Use of the Dvectis Double pad, Use of no pad
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- DD-Hippero s.r.o.
Spinal Stenosis
Comparison of Transforaminal vs. Parasagittal Interlaminar Epidural Injection
The purpose of this study is to compare the clinical efficacy, incidence of ventral epidural spreading and provocation of concordant paresthesia, amount of radiation exposure and total procedure time between transforaminal and…
- Trial name
- NCT02838615
- Testing
- epidural steroid (dexamethasone) injection
- Volunteers
- 56 people
- Sponsor
- Keimyung University Dongsan Medical Center
Recurrent Lumbar Disc Herniation
The Prediction of Recurrence Lumbar Disc Herniation At L5-S1 Level Through Machine Learning Models Based on Endoscopic Discectomy Via the Interlaminar Approach
What Was the Study About? This study focused on improving the care of patients with a specific type of back problem called lumbar disc herniation at the L5-S1 level.
- Trial name
- NCT06833099
- Testing
- VAS Point and Imaging Examination
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Jinyu Chen
Scoliosis, Scoliosis; Adolescence
Study Comparing the PathKeeper System for Pedicle Screw Positioning in Spine Surgery With Traditional Care
The goal of this is to evaluate performance of the Pathkeeper Surgical System. The main question[s]it aims to answer are: 1) evaluate pedicle screw position Participants will in compare Experimental arm: PathKeeper System (PKS)…
- Conditions
- Scoliosis, Scoliosis; Adolescence, Scoliosis Kyphosis, Scoliosis Lumbar Region
- Trial name
- PKSforPSP (NCT06554093)
- Testing
- Medical Device - PKS
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Deep Health Ltd.
Spinal Tuberculosis
Early Outcomes of Radical Debridement Versus no Debridement Under Different Surgical Procedures
Whether radical debridement is necessary for the treatment of thoracic and lumbar tuberculosis is still questionable. The objective of this prospective randomized study was to compare the outcomes of radical debridement versus no…
- Trial name
- NCT02638272
- Testing
- no debridement
- Volunteers
- 74 people
- Sponsor
- The Second Hospital of Anhui Medical University
Spinal Puncture
Randomized Evaluation of a Positioning Pillow for Lumbar Puncture in Paediatric Hematology-Oncology
We have developed a positioning cushion for LP which allows the child to be relaxed in an adequate position, and to maintain this position throughout LP.
- Trial name
- NCT00775112
- Testing
- pillow
- Where
- 2 sites in France
- Volunteers
- 124 people
- Sponsor
- Centre Leon Berard
Pain
Needle-Free Jet Injection of Lidocaine During Lumbar Puncture
Background: The J-Tip Device allows an intradermal needle-free jet injection of 1% buffered lidocaine. This study compares needle-free jet injection of lidocaine to saline in reducing pain prior to lumbar puncture in infants.
- Trial name
- NCT01224431
- Testing
- Buffered Lidocaine J-tip
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Phoenix Children's Hospital
Adolescent Idiopathic Scoliosis
Association Between Postural Balance and Muscle Activity of the Lumbar and Lower Limb Muscles in Female With or Without Adolescent Idiopathic Scoliosis (AIS) During Standing Balance Tasks With Upper Limb Movement
Adolescent idiopathic scoliosis (AIS) is the most common type of three-dimensional deformity of the spine in adolescence with a clear female predominance at a prevalence rate of 3.5% in Hong Kong.
- Trial name
- NCT05127902
- Testing
- Proprioceptive-stabilometric assessment machine (ProKin 252, TecnoBody®, Italy)
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- Tung Wah College
Degenerative Spine, Degeneration of Lumbar Intervertebral Disc
Percutaneous Trans-facet Spine Fixation
Percutaneous Trans-facet Fixation Massoud-Goel Technique and Theory for Treatment of Degenerative Spine
- Conditions
- Degenerative Spine, Degeneration of Lumbar Intervertebral Disc, Degenerative Cervical Disc Disease, Ligamentum Flavum Hypertrophy
- Trial name
- Massoud-Goel (NCT07001969)
- Testing
- Massoud-Goel Technique and Theory, Percutaneous Trans-facet Fixation for Treatment of Degenerative Spine
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Mahmoud Massoud