Clinical trials: MRI
Sedation for Children Undergoing MRI
A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI
The patients will be randomized into 2 equal groups by a computer-generated random numbers table, named group A, B. Group A: will receive oral Melatonin and nasal Sevoflurane.
- Trial name
- NCT06606899
- Testing
- Melatonin 3 MG, Chloral Hydrate, Sevoflurane
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anxiety, Sedation
Preparing Kids for MRI Using VR
Children frequently exhibit pre-MRI anxiety that can cause motion, repeated sequences, prolonged room time, and exposure to sedation.
- Conditions
- Anxiety, Sedation, Child, Virtual Reality
- Trial name
- NCT07203716
- Testing
- Virtual Reality Orientation (Home+Booster), Virtual Reality Orientation (Pre-Scan Only), Usual Care (No VR)
- Volunteers
- 150 people
- Sponsor
- Haseki Training and Research Hospital
Central Nervous System Disease, MRI
An Explainable Neuroradiologist Artificial Intelligence Assistance System for Brain CT and MRI
This clinic trial aims to validate the working performance of radiologists with or without artificial intelligence (AI) diagnostic tool at neurological diseases diagnosis on brain CT/MRI.
- Conditions
- Central Nervous System Disease, MRI, CT, AI (Artificial Intelligence)
- Trial name
- NCT07167043
- Testing
- AI-assisted diagnostic systems
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Yaou Liu
Focus of the Study is MRI Sequence Development
MRI Development for Radiotherapy Planning and Delivery in Non-Patient Volunteers
Non-patient volunteers will be scanned on the MR-Linac and MRSIM to facilitate the development, optimisation and validation of MRI protocols at The Christie NHS Foundation Trust.
- Trial name
- MINION (NCT04749134)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- The Christie NHS Foundation Trust
Clinical Indication for Brain MRI, Healthy Volunteers
Comparative Study of Conventional MR Images With Synthetically Reconstructed MR Images of the Brain
This study is being conducted for evaluation of 3D Synthetic MRI (SyMRI 15, 3D) for neuroimaging,
- Trial name
- NCT05425927
- Testing
- SyMRI 15 (3D)
- Where
- 6 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- SyntheticMR
Bone Metastases, Radiotherapy
Pain Relief in Symptomatic Bone Metastases With Adjuvant Hyperthermia MR Guided HIFU
Metastatic disease to the bone is a common cause of pain. External beam radiation therapy (EBRT) is the standard palliative treatment BUT pain improvement is observed in 60% to 80%.
- Conditions
- Bone Metastases, Radiotherapy, Pain, MRI
- Trial name
- BM-RT-HIFU (NCT05167669)
- Testing
- HIFU-MRI guided
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Sana Boudabbous
Renal Blood Flow, Anesthesia
MR-Evaluation of Renal Function in Anesthetized Pediatric Patients
The goal of this study is to investigate the effect of the anesthetic agents sevoflurane or propofol on the blood flow and oxygen delivery to the kidneys.
- Conditions
- Renal Blood Flow, Anesthesia, MRI, Renal Oxygenation
- Trial name
- MERAPED (NCT06876870)
- Testing
- Anesthesia Maintenance Agent
- Volunteers
- 50 people
- Sponsor
- Uppsala University
Patient With Radiotherapy (Linac MRI), Mobile Cancerous Lesion
Impact of Non-magnetic Screen Respiratory Self-guidance During MRI-guided Radiotherapy Sessions for Mobile Lesions
The patients eligible for the study are those treated by radiotherapy on Linac MRI for a mobile cancerous lesion (pancreas, liver, kidneys, adrenals, lung, adenopathy above or below the diaphragm ...).
- Trial name
- RespEcran (NCT05783908)
- Testing
- With non-magnetic screen
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Georges Francois Leclerc
NICU MRI
Clinical Use of a Neonatal MRI System
The purpose of the present study is to continue clinical scanning on the NICU MRI with improved administrative processes and procedures, thereby making medically indicated, state of the art/high end MRI exams available to all…
- Trial name
- NCT03476343
- Testing
- GE OPTIMA MR430s with HDx/GE Electronics
- Where
- United States
- Volunteers
- 386 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Status Epilepticus, Ictal-interictal Continuum
The Role of Imaging in the Diagnosis, Management and Prognosis of Possible Non-convulsive Status Epilepticus
The investigators propose a prospective study of 20 control subjects and 180 consecutive patients with possible non-convulsive status epilepticus (NCSE). The investigators will obtain three functional images of the brain: 1.
- Conditions
- Status Epilepticus, Ictal-interictal Continuum, Positron-emission Tomography, Perfusion Weighted MRI
- Trial name
- NCT06017973
- Testing
- MRI scan including arterial spin labelling of the brain, CT perfusion scan of the brain, FDG-PET scan of the brain
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
MRI in Breast Cancer
Role of MRI in Breast Cancer Subtypes
efficacy of MRI in detection of breast cancer molecular subtypes instead of biopsy and immunohistochemistry
- Trial name
- MRI (NCT06707584)
- Volunteers
- 45 people
- Sponsor
- Lamiaa Gomaa Ahmed Elsayed
Procedural Sedation, EEG
Factors Associated With Successful Completion of MRI in Children Undergoing a Vigil Sedation With Dexmedetomidin
This is a retrospective cohort study aiming to determine whether the use of Dexmedetomidine (DEX) to sedate children prior to MRI scanning is more or less effective in children with autism spectrum disorders or other…
- Conditions
- Procedural Sedation, EEG, MRI
- Trial name
- RIDEX (NCT06203522)
- Testing
- Data collection of successful completion of MRI
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Using Functional Lung MRI to Explore Pulmonary Perfusion Changes in Patients With Pulmonary Fibrosis and Emphysema Syndrome
Magnetic Resonance Lung Function Imaging Study of Pulmonary Fibrosis Combined With Emphysema Syndrome
This study intends to use magnetic resonance pulmonary function imaging technology to explore imaging markers for early diagnosis of patients with CPFE.
- Trial name
- NCT06431555
- Testing
- MRI
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
HNSCC, AI
10-year Retrospective Study of Oral and Maxillofacial Squamous Cell Carcinoma
Introduction: The incidence of occult cervical lymph node metastases (OCLNM) is reported to be 20%-30% in early-stage oral cancer and oropharyngeal cancer.
- Conditions
- HNSCC, AI, Radiomic, MRI
- Trial name
- NCT06366906
- Testing
- The Resnet50 deep learning (DL) model
- Where
- 2 sites in China
- Volunteers
- 319 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
MRI
VAPORHCS/OHSU J: MRI and Devices
This is a database study of clinically indicated MRIs on patients with permanent pacemakers and implantable cardioverter defibrillators.
- Trial name
- NCT03915015
- Testing
- MRI
- Where
- 2 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Oregon Health and Science University
Brain Injuries, Malaria
An MRI Ancillary Study of a Malaria Fever Investigation
This study will seek consent from parents of children enrolled in the Malaria FEVER study to obtain neuroimaging and 12-month neuropsychiatric outcomes data and kidney function on their child.
- Conditions
- Brain Injuries, Malaria, MRI Imaging, Neurocognitive Deficits
- Trial name
- MRIA (NCT05746819)
- Testing
- Aggressive antipyretics therapy of fever vs usual care in the Malaria RCT study
- Where
- 2 sites in Malawi, Zambia
- Volunteers
- 181 people
- Sponsor
- University of Rochester
Dexmedetomidine, Midazolam
Intranasal Dexmedetomidine Versus Intranasal Midazolam for MRI In Pediatrics
An increasing number of studies have reported the use of dexmedetomidine in clinical practice. However, few studies have reported on the intranasal use of dexmedetomidine in radiological procedures The aim of this work is to…
- Conditions
- Dexmedetomidine, Midazolam, MRI, Pediatrics
- Trial name
- NCT04652661
- Testing
- Dexmedetomidine, Midazolam
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
PET/MRI
Head-to-head Comparison Between [18F]-FDG PET/CT and PET/MRI in Lymphomas
Investigating the performance of 18F-FDG PET/CT and PET/MRI in lymphomas
- Trial name
- NCT05390632
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Cancer Hospital & Institute
MRI Sedation
Safety and Efficacy of Dexmedetomidine (DEX) for Sedation of Subjects ≥1 Month to <17 Years Undergoing MRI Scans
This is a randomized, double-blind, dose-ranging study of the efficacy and safety of dexmedetomidine (DEX) when used with propofol as needed, for procedural sedation of pediatric subjects ≥1 month to <17 years of age undergoing…
- Trial name
- NCT04237792
- Testing
- dexmedetomidine, propofol
- Where
- 23 sites in United States, Japan
- Volunteers
- 128 people
- Sponsor
- Pfizer
MRI
MRI Assessing Clinical Usability of STrategically Acquired Gradient Echo on Human Participants
The study's purpose is to validate STAGE images and, when applicable, their equivalence to conventional MRI through an assessment by a trained certified neuroradiologist in a clinical setting.
- Trial name
- STAGE (NCT04292301)
- Testing
- STrategically Acquired Gradient Echo (STAGE)
- Where
- 5 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- SpinTech, Inc.