Clinical trials: Malocclusion
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
The Use of Clear Aligners With Movement Enhancement Techniques
The purpose of this study is to use clear aligners to measure tooth movement and length of treatment.
- Trial name
- NCT02087163
- Testing
- Movement Enhancement Technique, Clear Aligner
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusions, Narrow Maxilla
Hyrax Vs. Invisalign Palatal Expander Clinical Study
The purpose of this study is to compare expansion result and the overall experience between the Invisalign Palatal Expander and the Hyrax expander.
- Conditions
- Malocclusions, Narrow Maxilla, Narrow Maxillary Arch, Crowding
- Trial name
- NCT06662279
- Testing
- Removable Rapid Palatal Expander, Banded Palatal Expander
- Where
- 4 sites in United States
- Volunteers
- 36 people
- Sponsor
- Align Technology, Inc.
Malocclusion, Angle Class II, Division 1
Early Treatment for Class II Division 1 Malocclusion With Twicare® and Herbst Removable Appliances
The aim of this prospective, multicentric, randomized, open-label study is to assess the efficacy of the removable Twicare® as mandibular propulsive appliance in children aged from 7 to 12 years old in the course of their…
- Trial name
- EffTwicare (NCT02428621)
- Testing
- Twicare® appliance, Removable Herbst appliance
- Where
- 3 sites in France
- Volunteers
- 62 people
- Sponsor
- FCI System
Malocclusion
Class II Correction Study Using the Invisalign System
To demonstrate that growing teenagers which present up to full cusp Class II malocclusions can be treated using the Invisalign System.
- Trial name
- NCT02376829
- Testing
- Invisalign System
- Where
- 10 sites in United States, Canada
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Malocclusion
Evaluation of Clear Aligner Trays to Straighten Teeth
The objective of this study is to evaluate the efficacy of Clear Aligners to correct tooth malocclusions with the use of attachments and/or buttons, as determined by the amount of teeth movement and overall achievement goals of…
- Trial name
- NCT03141788
- Testing
- Clear Aligner
- Where
- 9 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Solventum Orthodontics Corporation
Malocclusion
The Effect of Ultrasound on Orthodontic Tooth Movement
To study whether or not the Aevo System™ medical device enhances the rate of tooth movement in human subjects who use orthodontic braces.
- Trial name
- NCT01828164
- Testing
- Ultrasound
- Where
- 5 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SmileSonica Inc.
Malocclusion
Effect of Cyclic Loading (Vibration) on Orthodontic Tooth Movement
To gather data indicating whether or not the OrthoAccel device speeds tooth movement in people who use orthodontics (braces).
- Trial name
- NCT00830947
- Testing
- OrthoAccel Device
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- OrthoAccel Technologies Inc.
Malocclusion
The Effects of Extraoral Photobiomodulation on the Rate of Orthodontic Alignment
The aim of this study is to determine if extraoral OrthoPulse®, which emits extraoral LED (Light Emitting Diode) photobiomodulation (PBM), reduces the time it takes to complete orthodontic alignment.
- Trial name
- NCT02267824
- Testing
- Extraoral OrthoPulse® PBM, Fixed Orthodontic Appliance Treatment
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 101 people
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
One Week Aligner Evaluation
The purpose of this study is to demonstrate that changing aligners weekly provides similar results to changing aligners every two weeks.
- Trial name
- NCT02603289
- Testing
- Invisalign
- Where
- 24 sites in United States, Canada
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Dental Crowding, Malocclusion, Angle Class I
Treatment Outcome of Elastomeric and Nickel-Titanium Separators in Tooth Separation
Patients seeking fixed orthodontic treatment that requires band placement will be enrolled in this study. This trial aims to compare the efficiency of rectangular cross-section nickel-titanium separators with elastomeric…
- Trial name
- NCT07591454
- Testing
- Elastomeric separators, Nickel-Titanium separators
- Volunteers
- 30 people
- Sponsor
- 3D-Aligners
Class II Malocclusion, Mandibular Advancement
Invisalign® System with Mandibular Advancement
The goal of this clinical trial is to observe study participants' comfort and fit of their aligners with occlusal blocks, as well as evaluate the engagement of the blocks using the Invisalign® System with mandibular advancement…
- Conditions
- Class II Malocclusion, Mandibular Advancement, Mandibular Retrognathism, Excessive Overjet
- Trial name
- NCT06651944
- Testing
- Invisalign® System with mandibular advancement featuring occlusal blocks
- Where
- 3 sites in Canada
- Volunteers
- 36 people
- Sponsor
- Align Technology, Inc.
Dental Malocclusion
Precision Orthodontics: A Comparison of Custom vs Traditional Bracket Treatment Efficiency
This investigational testing aims to target multiple investigations sites to examine treatment efficiency metrics using a completely digital and patient-specific bracket treatment system for the correction of malocclusions.
- Trial name
- NCT04266769
- Testing
- LightForce Orthodontic System
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- LightForce Orthodontics
Malocclusion
The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances
The aim of this study is to determine efficacy of OrthoPulse photobiomodulation on the rate of tooth movement during alignment for Subjects receiving fixed appliance orthodontic treatment.
- Trial name
- NCT03202355
- Testing
- Fixed Appliance Orthodontic Treatment, OrthoPulse™
- Where
- 3 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time
The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on orthodontic treatment time.
- Trial name
- NCT02267850
- Testing
- Fixed Orthodontic Appliance Treatment, OrthoPulse™, Non-Functional OrthoPulse™
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Biolux Research Holdings, Inc.
Dental Malocclusion, Edentulous Mouth
Safety and Technical Performance of Plastalgin and Plastalgin Fast in Patients Requiring a Dental Impression
The aim of this study is to gather clinical data related to the use of Plastalgin and Plastalgin Fast, in order to comply with the new medical device regulation.
- Conditions
- Dental Malocclusion, Edentulous Mouth, Dental Misalignment
- Trial name
- NCT05614635
- Testing
- Plastalgin and Plastalgin Fast
- Where
- 2 sites in France
- Volunteers
- 59 people
- Sponsor
- Septodont
Malocclusion
OrthoPulse™ and Its Effect on the Rate of Orthodontic Tooth Alignment: A Pilot Feasibility Study
The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on the rate of anterior orthodontic alignment.
- Trial name
- NCT02267837
- Testing
- OrthoPulse™
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion
EXD-959 Orthodontic Brackets and EXD-961 Related Instruments Trial
The purpose of this study is to assess the performance of the EXD-959 self-ligating ceramic bracket system using EXD 961 instruments in the treatment of orthodontic malocclusion.
- Trial name
- NCT03606551
- Testing
- EXD-959 Bracket System
- Where
- 5 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- 3M
Malocclusion
The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement
This open label study is designed to evaluate the ability of OrthoPulse™ to safely and effectively increase the rate of orthodontic tooth movement with fixed appliances.
- Trial name
- BX8RN (NCT02267811)
- Testing
- Orthodontic Treatment, OrthoPulse™
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Biolux Research Holdings, Inc.