Clinical trials: Mandible Prognathism
Skeletal Class III Malocclusion
Figuring Out the Genetic Mutations That Lead to Lower Jaw Advancement More Than the Upper Jaw
Purpose of the Research: To reveal the genetic cause for the occurrence of Class III malocclusion, or what may be described as a reverse bite (underbite). Introduction and Detailed Procedures for the Patient (Work Plan): 1.
- Trial name
- NCT07749638
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Cairo University
Mandibular Prognathism
Patient Satisfaction Vertical Ramus Osteotomy Patient Specificosteosynthesis Fixation Versus MMFmandibular Prognanthism
Two groups with mandibular prognanthism indicated for mandibular setback by intraoral vertical ramus osteotomy . first group will fixed with maxillomandibular fixation and the second group will fixed by customized plate
- Trial name
- NCT03855072
- Testing
- customized fixation plate, maxillomandibular fixation
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class III Malocclusion
Treating Growing Patients With Mandibular Prognathism and Maxillary Constriction
This randomized controlled trial intends to test the efficacy of two treatment protocols in the correction of Class III malocclusion with maxillary constriction.
- Trial name
- NCT06762418
- Testing
- RMR+SME, BAIMT+RME
- Where
- 2 sites in Syria
- Volunteers
- 26 people
- Sponsor
- Damascus University
Class III Malocclusion
The Effects of the Chin Cup on Temporomandibular Joint and Mandibular Dimensions
This in vivo comparative study will evaluate the changes in the mandibular dimensions and the glenoid fossa after skeletal class III subjects' therapy by chincup appliance and compare it with an untreated class III control group.
- Trial name
- NCT05350306
- Testing
- Chincup, Control group
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Class II Division 1 Malocclusion, Maxillary Prognathism
Laser-assisted Flapless Corticotomy in Accelerating Canine Retraction
Erbium lasers have been suggested to accomplish corticotomy without flap reflection due to their attractive advantages. The current trial aimed to evaluate the efficacy of laser-assisted flapless corticotomy in accelerating…
- Conditions
- Class II Division 1 Malocclusion, Maxillary Prognathism, Protrusion, Incisor
- Trial name
- NCT04316403
- Testing
- Er:YAG laser
- Where
- Syria
- Volunteers
- 18 people
- Sponsor
- Damascus University
Class III Malocclusion, Cross Bite
Evaluation of Pain, Discomfort and Acceptance During the Orthodontic Treatment of Class III Malocclusion
The aim of this study is to evaluate the levels of pain, discomfort and acceptance between two treatment modalities of Class III correction of growing patients in the late mixed dentition period.
- Conditions
- Class III Malocclusion, Cross Bite, Orthodontic Appliance Complication
- Trial name
- NCT03976635
- Testing
- Removable Mandibular Retractor, Bone-anchored intermaxillary traction
- Where
- Syria
- Volunteers
- 38 people
- Sponsor
- Damascus University
Class III Malocclusion in Growing Patients
Changes Following the Treatment of Lower Jaw Protrusion Using Two Appliances
An in vivo study evaluating the efficacy of the Tandem appliance in the treatment of maxillary deficiency in growing patients compared to the conventional facemask appliance treatment.
- Trial name
- NCT02144324
- Testing
- Tandem Appliance
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Class III Malocclusion
Mandibular First Molar Distalization
A clinical study to test the capability of the mini-screws inserted in the Mandibular buccal shelf area as an anchorage unit to distalize mandibular first molar for correction of mild to moderate Class III cases.
- Trial name
- NCT04229797
- Testing
- Mandibular distalization using extra-radicular miniscrews
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anterior Crossbite, Class III Malocclusion
Evaluation of the Treatment Effects of Tooth Borne Versus Bone-anchored Protraction Procedures in Class III Patients With Maxillary Deficiency
The aim of this prospective randomized controlled clinical study is to compare the effects of bone-anchored and tooth borne maxillary protraction on dentofacial structures in skeletal Class III patients.
- Conditions
- Anterior Crossbite, Class III Malocclusion, Maxillary Deficiency
- Trial name
- NCT04863404
- Testing
- Face mask with hybrid-hyrax, Face mask with conventional bonded RME
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Class III Malocclusion
Assessment of Maxillary Stability in Bimaxillary Orthognathic Patients Using the Inverted Sequence Approach
The investigator will assess the inverted sequence approach in the treatment of class III patient undergoing bimaxillary orthognathic surgery
- Trial name
- NCT03353116
- Testing
- the mandible first, the maxilla first
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Palatal Expansion Technique, Cleft Lip and Palate
MARPE in Patients With Cleft Lip and Palate
The objective of this randomized controlled study will be to evaluate the dental and skeletal effects of maxillary protraction with a facemask, associated with MARPE and Class III elastics in patients with unilateral cleft lip…
- Conditions
- Palatal Expansion Technique, Cleft Lip and Palate, Class III Malocclusion, Skeletal Malocclusion
- Trial name
- NCT04354116
- Testing
- Rapid maxillary expansion, Maxillary Protraction
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Prognathism, Retrognathia
Transoral Versus Transbuccal Placement of Bicortical Screws During Orthognathic Surgery
Bicortical screws have been widely used for mandibular osteosynthesis during orthognathic surgery.Transoral placement of bicortical screws is a rigid fixation method in orthognathic surgery, which is less often used.
- Conditions
- Prognathism, Retrognathia, Jaw Abnormalities
- Trial name
- NCT02658305
- Where
- Belgium
- Volunteers
- 509 people
- Sponsor
- AZ Sint-Jan AV
Class III Malocclusion, Maxillary Deficiency
Evaluation of Pain and Functional Impairments When Treating Class III Malocclusion Using Two Treatment Procedures
A clinical examination of each recalled candidate patient will be carried out at Adib Al Lahham Centre at the Ministry of Health Damascus to ensure that he/she meets the inclusion criteria.
- Trial name
- NCT06877780
- Testing
- RMR with SME, BAIMT with RME
- Where
- Syria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Damascus University
Class III Malocclusion, Skeletal Malocclusion
Comparison of Skeletal Anchorage Versus Conventional Tooth-Borne Face Mask Therapy Following the Alt-RAMEC Protocol
This study investigated two different methods of maxillary protraction in growing patients with skeletal Class III malocclusion characterized by maxillary deficiency.
- Conditions
- Class III Malocclusion, Skeletal Malocclusion, Maxillary Deficiency
- Trial name
- MiniFM (NCT07279662)
- Testing
- Skeletal Anchorage Supported Maxillary Protraction, Tooth-Borne Maxillary Protraction Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Murat Kaan Erdem
Prognathism, Retrognathism
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Background: Some head and facial abnormalities are rare and present at birth. Others are more common, and may not show up until puberty. These conditions have different causes and characteristics.
- Conditions
- Prognathism, Retrognathism, Dentofacial Deformities
- Trial name
- NCT02639312
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Class I Malocclusion, Maxillary Prognathism
Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper Arch
study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.
- Conditions
- Class I Malocclusion, Maxillary Prognathism, Orthodontic Tooth Movement
- Trial name
- NCT07521267
- Testing
- Silver nanoparticles, uncoated titanium miniscrews
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Al-Azhar University
Class III Malocclusion
Evaluating the Effectiveness of the Lower-Clear-Plate-Based Intermaxillary Traction
Patients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT06596239
- Testing
- lower-clear-plate-based intermaxillary traction (LCP-IMT), Removable mandibular retractor (RMR)
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Malocclusion, Angle Class III
Treatment of Class III Malocclusion Using Modified Fixed Mandibular Retractor Appliance
This experimental study aims to evaluate the efficiency of the Modified Fixed Mandibular Retractor Appliance in the treatment of skeletal class III malocclusion.
- Trial name
- NCT03354442
- Testing
- Modified Fixed Mandibular Retractor Appliance
- Where
- Syria
- Volunteers
- 44 people
- Sponsor
- Damascus University
Retrognathism, Prognathism
Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy
The bilateral sagittal split osteotomy (BSSO) of the mandible is one of the most used surgical techniques to achieve a harmonious jaw relation in the context of orthognathic surgery.
- Conditions
- Retrognathism, Prognathism, Orthognathic Surgery, Neurosensory Disorder
- Trial name
- NCT05536596
- Testing
- Orthognathic Surgery, Melatonin 10 MG Oral Tablet, Hydroxycobalamin
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Class III Malocclusion
Patient Specific Intraoral Inverted-L Osteotomy Modified With Inferior Alveolar Nerve Relocation in Corrective Mandibular Surgery
Bilateral sagittal split osteotomy (BSSO) is considered the main osteotomy design in corrective mandibular surgery, however abnormal anatomical configuration of the posterior mandible with rolled out inferior border and thin…
- Trial name
- NCT05397002
- Testing
- patient specific inverted L mandibular osteotomy modified with inferior alveolar nerve relocation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University