Clinical trials: Masses
Neck Mass, Thyroglossal Duct Cysts
Computer Aided Tool for Diagnosis of Neck Masses in Children
The aim of this study was to evaluate the diagnostic efficacy of computer aided diagnostic tool for neck masses using machine learning and deep learning techniques on clinical information and radiological images in children.
- Conditions
- Neck Mass, Thyroglossal Duct Cysts, Branchial Cleft Anomalies, Dermoid and Epidermoid Cysts
- Trial name
- NCT05187923
- Testing
- Artificial Intelligence Algorithm
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- West China Hospital
Pediatric Tumor
Role of Gray Scale and Color Doppler Ultrasound in Diagnosis of Pediatric Neck Masses
Our aim is to assess the role of the gray scale and color Doppler ultrasound in diagnosis of the different pediatric neck masses .
- Trial name
- NCT04856020
- Volunteers
- 96 people
- Sponsor
- Assiut University
Complex Adnexal Masses
MRI Perfusion in Adnexal Masses
As ovarian cancer is characterized by an anarchic neovascularization resulting in a wide number of immature microvessels. These vessels are characterized by a lack of coverage by pericytes and the higher expression of one of the…
- Trial name
- MRI-CAM (NCT02694406)
- Testing
- MRI perfusion
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Sellar Mass, Pituitray Tumor
Sellar Masses: Clinical and Imaging Features With Correlation to Histopathology and Surgical Approach
The goal of this observational study is to learn about the clinical spectrum of sellar masses, aiming to understand the correlation between the imaging features and the future surgical approach and histopathology results.
- Trial name
- NCT07633860
- Testing
- Craniectomy
- Where
- Yemen
- Volunteers
- 49 people
- Sponsor
- Arab Board of Neurosurgery
Breast Cancer
Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy
Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.
- Trial name
- NCT04428528
- Testing
- Photoacoustics Imaging System
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Ovarian; Mastopathy
The Value of the O-RADS Radiological Classification in Predicting the Malignancy of Ovarian Masses in Children
When faced with an ovarian mass in a girl, conservative surgery (resection of the mass while preserving healthy ovarian tissue) via laparoscopy remains the most appropriate treatment option.
- Trial name
- MMO (NCT07313514)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Pancreatic Cancer, Endoscopic Ultrasound
Ex-vivo Ultrasound Guided Radiofrequency Ablation on Pancreatic Solid Lesions
The study investigates the feasibility and the efficacy to treat pancreatic solid lesions as pancreatic adenocarcinomas (PDAC) and neuroendocrine tumors (NET) with ex-vivo radiofrequency ablation (RFA) under ultrasound (US)…
- Conditions
- Pancreatic Cancer, Endoscopic Ultrasound, Radiofrequency Ablation
- Trial name
- NCT06371716
- Testing
- ex-vivo RFA under US control at 10 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 30 Watts (W) of power in 3 differents arms of lesions, ex-vivo RFA under US control at 50 Watts (W) of power in 3 differents arms of lesions
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS San Raffaele
Breast Cancer, Breast Masses
Three-Dimensional Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
The purpose of the study is to test the hypothesis that quantitative ultrasound techniques including spectroscopy may be used as a non-invasive biomarker for characterization of suspected breast cancers.
- Trial name
- NCT06175078
- Testing
- Ultrasound Imaging 3D and Spectroscopy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Sunnybrook Health Sciences Centre
Silent; Thrombosis
Detection of Asymptomatic Venous Thrombosis in Gynecological Patients With Pelvic Masses
Venous thromboembolism (VTE) is a serious preventable complication of gynecological surgery. High incidence of silent VTE before surgery seems attributable to the high incidence of VTE after surgery in ovarian cancer .so the aim…
- Trial name
- NCT03260270
- Testing
- color doppler ultrasound
- Volunteers
- 60 people
- Sponsor
- Assiut University
Mediastinal Tumor
Assessment of Mediastinal Masses With Diffusion Weighted MR Imaging
Differentiation between benign and malignant mediastinal tumors as well as characterization and grading of malignancy which is essential for treatment planning as well as for prognosis
- Trial name
- NCT03214341
- Testing
- MRI diffusion
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Assiut University
Uterine Tumor
Diagnostic Value of Transcervical True-Cut Biopsy in Uterine Masses
Uterine tumor-like masses represent a wide spectrum of gynecological conditions, ranging from benign lesions such as myomas and adenomyosis to malignant tumors like endometrial carcinoma and leiomyosarcoma, as well as other…
- Trial name
- NCT07264660
- Testing
- Transcervical True-Cut Biopsy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assiut University
Teratomas, Mediastinal ( Chest) Masses
Subxiphoid VATS for Giant Mediastinal Teratoma
For giant mediastinal teratomas, the only treatment option available is usually open-chest surgery, which causes significant trauma, leads to obvious postoperative pain and may result in long-term complications such as chest wall…
- Conditions
- Teratomas, Mediastinal ( Chest) Masses, VATS
- Trial name
- NCT07199699
- Testing
- Subxiphoid Minimally Invasive Resection of Giant Mediastinal Teratoma Assisted by Double Sternal Elevation
- Volunteers
- 40 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Adnexal Mass, Adnexal Tumor
Masses in Young Patients - International Ovarian Tumour Analysis (MY-IOTA)
This multicenter observational study aims to validate the IOTA Simple Rules, Benign Descriptors, and ADNEX model in a cohort of patients equal or under the age of 20.
- Conditions
- Adnexal Mass, Adnexal Tumor, Adnexal Cyst, Adnexal Masses in Young Girls and Adolescents
- Trial name
- MY-IOTA (NCT06693596)
- Testing
- Group 2: Conservative management (follow-up), Group 1: Surgical management
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
LOW AND INTERMEDIATE PAEDIATRIC NEUROBLASTOMA AND NEONATAL SUPRARENAL MASSES
European Low and Intermediate Risk Neuroblastoma Protocol
The European study, LINES 2009 (Low and Intermediate Risk Neuroblastoma European Study), groups together in a single protocol the treatment of all patients with "non high risk" neuroblastoma (NB), with stratification into two…
- Trial name
- NCT01728155
- Testing
- chemotherapy
- Where
- 98 sites in Australia, Austria and 8 more
- Volunteers
- 685 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Adnexal Mass
The Use of International Ovarian Tumor Analysis and Assessment of Adnexal Neoplasia in Differentiating Malignant and Benign Adnexal Masses
All participants will be subjected to Serum measurements of CA-125 by the immunoradiometric assay, Ultrasound evaluation of the Adnexal masses which is described according to origin (ovarian/extraovarian); position…
- Trial name
- NCT03442881
- Testing
- Excision of adnexal mass through laprotomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Breast Cancer
Investigation of Ultrasound Imaging and Spectroscopy for Characterizing Breast Masses
Our objective in this study is to identify an optimal set of quantitative ultrasound parameters that can be used, non-invasively, to characterize breast masses with high accuracy, as determined histopathologically.
- Trial name
- NCT04050423
- Where
- Canada
- Volunteers
- 1,200 people
- Sponsor
- Sunnybrook Health Sciences Centre
Patients With Adnexal Mass Prior to Surgery
Prospective Validation and Comparison of Different Ultrasound Methods for Discrimination Between Benign and Malignant Ovarian/Tubal Masses Prior to Surgery
The ability of different methods to discriminate between benign and malignant adnexal masses has been compared in a meta-analysis showing that the IOTA Simple Rules and the IOTA logistic regression model LR2 were superior to RMI…
- Trial name
- IOTA7 (NCT02847832)
- Testing
- Standardized transvaginal ultrasound examination
- Where
- Belgium
- Volunteers
- 1,700 people
- Sponsor
- KU Leuven
Osteosarcoma
Single High-dose Brachytherapy for Giant Osteosarcoma Masses
This study is a prospective, single-arm, phase II, single-center study. Patients with locally unresectable giant osteosarcoma masses who meet the criteria are enrolled in the experimental group, and all patients receive a single…
- Trial name
- NCT06524778
- Testing
- brachytherapy
- Volunteers
- 16 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Pancreatic Neoplasm, Pancreatic Cyst
Percutaneous Versus EUS FNAC in Pancreatic Masses
We aim to evaluate the role of Ultrasound-guided (USG) fine needle aspiration cytology (FNAC) in diagnosis of pancreatic masses compared to endoscopic ultrasound (EUS) guided fine needle aspiration cytology (FNAC).
- Conditions
- Pancreatic Neoplasm, Pancreatic Cyst, Pancreatic Abscess
- Trial name
- NCT04623749
- Testing
- US, EUS
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ola Kamal Mohammed Galal
Soft Tissue Masses
MAGNETIC RESONANCE IMAGING in Superficial Soft Tissue Masses
This study responds to these raise up questions: Can we use Diffusion Weighted MR complemented with numerical ADC values \& in association with routine MRI in the discrimination between different malignant and benign superficial…
- Trial name
- NCT05079997
- Testing
- MAGNETIC RESONANCE IMAGING
- Volunteers
- 50 people
- Sponsor
- Assiut University