Clinical trials: Modification
Atopic Dermatitis (Eczema), Atopic Dermatitis, Probiotics
Prebiotic Effects of Mulberry Fruit in Children and Adolescents With Atopic Dermatitis
This project proposes a randomized controlled human study to explore the prebiotic effects of consuming mulberry juice on atopic dermatitis in children and adolescents.
- Trial name
- NCT06636240
- Testing
- Mulberry fruit juice, Mometasone furoate 0.1% cream
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Cerebral Palsy
Can Gait Analysis and Ultrasound Detect a Change in Calf Musculature in Children With Cerebral Palsy?
ORLAU is a clinical department of the Robert Jones and Agnes Hunt Orthopaedic Hospital. We treat patients with a wide range of movement disorders affecting their walking or arm function.
- Trial name
- NCT04290689
- Testing
- Botulinum Toxin-A injection, Serial casting stretching
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Appendicitis
Appendicitis During the National Lockdown During the COVID-19 Pandemic
The study aims to examine whether a nationwide lock-down with an entire population subjugated to social distancing reduces the incidence of appendicitis.
- Trial name
- NCT04407117
- Testing
- Lock-down and social distancing
- Where
- Denmark
- Volunteers
- 6,000,000 people
- Sponsor
- Claus Anders Bertelsen, PhD, MD
Diabetes Mellitus, Type 1, Diabetes Mellitus
Azithromycin Insulin Diet Intervention Trial in Type 1 Diabetes
Increasing evidences suggest that infections are important etiological factors for the development of Type 1 Diabetes (T1D). The overall hypothesis of the study is that the treatment of children, during the first year after…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Metabolic Disease, Glucose Metabolism Disorders
- Trial name
- AIDIT (NCT03682640)
- Testing
- Azithromycin Monohydrate, Insulin Lispro, Dietician support
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
Diabetic Nepheopathy
Role of Renal Duplex Resistive Index (RRI) and Pulsatility Index (PI) in Assessment of Early Renal Microvascular Changes in Diabetic Patient
Diabetes mellitus (DM) is a globally prevalent metabolic disorder with an escalating burden on renal health. Diabetic kidney disease (DKD) represents the leading cause of end-stage renal disease (ESRD) worldwide, affecting…
- Trial name
- NCT07864740
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Assiut University
Psychological Distress, Insomnia
Clinical Trial for Acupuncture in Adolescents With Psychological Distress and Insomnia
This is an assessor-blinded, randomized, MAS-controlled trial. A total of 148 adolescents aged 15-22 years experiencing mild to moderate anxiety or depressive symptoms will be recruited.
- Trial name
- NCT06638450
- Testing
- Dense Cranial Electroacupuncture Stimulation plus Body Acupuncture (DCEAS+BA), Minimal Acupuncture Stimulation (MAS)
- Where
- Hong Kong
- Volunteers
- 148 people
- Sponsor
- The University of Hong Kong
Cancer, Malignant Neoplasm
Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
The primary objective of this study is to evaluate the feasibility and acceptability of obtaining repeated measurements of lean muscle mass, physical function, and biological aging in children receiving active cancer therapy.
- Trial name
- NCT05823740
- Testing
- Bioelectrical impedance Analysis (BIA), D3-Creatine Dilution (D3Cr), 6-Minute Walk Test (6MWT)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Endodontically Treated Teeth, Endodontical Retreatment
Broken Instrument Removal
The aims of this retrospective analysis are (1) to evaluate the success rate of a non-surgical retreatment of teeth with broken file instrument into the canal using ultrasounds, microscope and a modified spinal needle, (2) to…
- Trial name
- NCT05128266
- Testing
- Endodontical Retreatment
- Volunteers
- 161 people
- Sponsor
- Catholic University of the Sacred Heart
Pneumonia, Diarrhea, Fever
Treatment of Pneumonia, Diarrhoea and Fever in Children by Community Health Workers
The investigators propose to test the feasibility and acceptability of community health workers (ASHAs and ANMs) being able to treat sick children in the community.
- Trial name
- NCT02623166
- Where
- India
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Unilateral Cleft Lip
Effect of Platelet Rich Plasma (PRP) on the Esthetic Outcome and Scar Formation of Unilateral Cleft Lip Repair
The purpose of this study is to evaluate effect of platelet rich plasma on scar formation of unilateral cleft lip repair.
- Trial name
- NCT02958306
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Anorexia Nervosa
Improving the Treatment of Anorexia Nervosa in Children Through Virtual Reality Body Exposure
The age of onset of anorexia nervosa has been progressively decreasing in recent years. Also, the prevalence rates of childhood anorexia in many countries have grown significantly.
- Trial name
- EOAN-VR-ABM (NCT06166355)
- Testing
- Attentional Bias Modification Training, VR-based body exposure, Cognitive-behavioral therapy
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- University of Barcelona
Cannabis Use, Cognitive Change
Cognitive Recovery With Cannabis Abstinence Among High School-Aged Adolescents
This study will use a randomized controlled design to test whether 30 days of cannabis abstinence, compared to 30 days of monitoring, is associated with improvements in cognitive functioning.
- Conditions
- Cannabis Use, Cognitive Change, Adolescent Behavior
- Trial name
- NCT03276221
- Testing
- Abstinence
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
VTE
Exercise Training After an Acute Blood Clot
Patients after an acute blood clot in the veins are at risk for leg-related complications such as pain, swelling, and immobility.
- Trial name
- TRAIN ABC (NCT01864447)
- Testing
- VTE REHABILITATION: High-Caloric Expenditure Exercise Training (HCE) and The Dietary Behavioral Weight Loss Intervention (BWL)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Lyme Disease
A School-Based Intervention to Reduce Lyme Disease
Our overall purpose of this study is evaluate whether a short in-class Lyme Disease education program based on social learning theory and the Health Belief Model can impact a child's knowledge, attitude, and preventive behavior.
- Trial name
- NCT00594997
- Testing
- Education, Control (pre and post surveys)
- Volunteers
- 3,570 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anxiety Disorders, Depression
Unified Protocol for Adolescents (UP-A) Change Processes
The purpose of this protocol is to employ single case analytic strategies, including a multiple baseline design and novel modeling techniques to identify changes in cross-cutting features of emotional disorders as well as…
- Conditions
- Anxiety Disorders, Depression, Obsessive-Compulsive Disorder, Adolescent - Emotional Problem
- Trial name
- NCT03102008
- Testing
- Unified Protocol for Emotional Disorders in Adolescents (UP-A)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Vomiting, Diarrhea
Developing World Study for RotaTeq™ (V260-015)(COMPLETED)
The purpose of the current study is to evaluate whether the vaccine is effective, well-tolerated and immunogenic among infants in developing countries.
- Conditions
- Vomiting, Diarrhea, Fever
- Trial name
- NCT00362648
- Testing
- RotaTeq™ - Rotavirus Vaccine, Live, Oral, Pentavalent
- Volunteers
- 7,504 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Obesity, Obesity, Childhood
A Novel Obesity Prevention Program for High-Risk Infants in Primary Care
The goal of this clinical trial is to test a responsive parenting obesity prevention program with infants and caregivers of color (e.g., non-White; Hispanic/Latinx) and/or who are economically marginalized (i.e., publicly…
- Conditions
- Obesity, Obesity, Childhood, Weight Gain, Weight Gain Trajectory
- Trial name
- THRIVE (NCT06028113)
- Testing
- THRIVE 2.0
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Appendicitis, Gastroenteritis
Study on the Difference of Axilo-rectal Temperature in Appendicitis
The investigators are studying prospectively the difference in axilo-rectal temperature in patients with acute appendicitis and using as a control group patients consulting with acute gastroenteritis at our emergency unit.
- Trial name
- NCT00674726
- Testing
- Observation and measurement of axilo-rectal temperature
- Where
- 2 sites in Chile
- Sponsor
- Cirujanos la Serena
Emotion Regulation
Neuroplastic Adaptations in Youth at High Risk for Developing Psychopathology
This pilot study aims to inform decision-making for a bigger study we intend to conduct in the future. The larger investigation will explore how helpful a treatment program for youth (ages 17 - 24) with emotion dysregulation (ED)…
- Trial name
- NCT05586425
- Testing
- Emotion Regulation Skills + Treatment as Usual, Treatment as Usual
- Volunteers
- 20 people
- Sponsor
- McMaster University
Fetal Growth Abnormalities, Fetal Weight
Impact of AI Feedback on Ultrasound Biometry Accuracy Across the Expertise Levels
Objective: To evaluate the impact of real-time AI feedback on fetal biometry accuracy and investigate the Expertise Reversal Effect-whether AI benefits diminish as user experience increases.
- Trial name
- NCT07476638
- Testing
- AI interventional group
- Where
- 3 sites in Denmark
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
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