Clinical trials: Modification
Crohn Disease, Ulcerative Colitis
Changes in Faecal Calprotectin Levels and Participation-related Scores Following Three Weeks of Inpatient Rehabilitation
For many people affected by inflammatory bowel disease (IBD), their quality of life and their ability to participate in their professional and social lives are severely restricted.
- Trial name
- NCT05500040
- Testing
- Multimodal Rehabilitation
- Where
- Austria
- Volunteers
- 226 people
- Sponsor
- Pensionsversicherungsanstalt
Well-being, Life Style, Healthy
Effect of #LIFEGOALS on Adolescents' Mental Health
The aim of this study is to evaluate the effectiveness of the #LIFEGOALS intervention for promoting mental health in early adolescents.
- Conditions
- Well-being, Life Style, Healthy, Resilience, Depressive Symptoms
- Trial name
- MOV-E-STAR (NCT04719858)
- Testing
- #LIFEGOALS
- Where
- Belgium
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University Ghent
Autistic Disorder
Motor Learning and Brain Changes in Autism
The purpose of this pilot study is to determine whether a video-game based motor training can affect postural stability, daily living skills, autism symptoms, and white matter microstructure of the corticospinal tract in…
- Trial name
- NCT02358317
- Testing
- Video Game Motor Training, Sedentary Video Game Training
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Appendicitis
Appendicitis During the National Lockdown During the COVID-19 Pandemic
The study aims to examine whether a nationwide lock-down with an entire population subjugated to social distancing reduces the incidence of appendicitis.
- Trial name
- NCT04407117
- Testing
- Lock-down and social distancing
- Where
- Denmark
- Volunteers
- 6,000,000 people
- Sponsor
- Claus Anders Bertelsen, PhD, MD
Adolescence Obesity
Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents
This is a Phase Ib, randomized, double-blind, placebo-controlled clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Efsubaglutide Alfa Injection following multiple-dose…
- Trial name
- NCT07693426
- Testing
- Efsubaglutide Alfa 5 mg QW, Efsubaglutide Alfa 10 mg QW, Efsubaglutide Alfa 20 mg QW
- Where
- 5 sites in China
- Volunteers
- 36 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Develop a New Group Version of the Becker-DeGroot-Marsckek (BDM) Auction to Measure Willingness to Pay of Compound Members for Shared Hardware., Develop a New Survey Instrument to Measure Behavioural Determinants of Hand Washing and Water Treatment Like Disgust and Shame or Social Pressure.
Disgust and Shame Based Safe Water and Handwashing Promotion
An estimated 2.2 million children under the age of 5 years die from diarrheal disease each year. Most of the burden of diarrheal disease is thought to be preventable with improvements in sanitation, water quality, and hygiene.
- Conditions
- Develop a New Group Version of the Becker-DeGroot-Marsckek (BDM) Auction to Measure Willingness to Pay of Compound Members for Shared Hardware., Develop a New Survey Instrument to Measure Behavioural Determinants of Hand Washing and Water Treatment Like Disgust and Shame or Social Pressure., Identify New Methods for Measuring Hand Washing and Water Treatment Behaviour., Compare the Effectiveness of the Disgust and Shame Based Interventions With Standard Public Health Interventions.
- Trial name
- NCT02037243
- Testing
- Standard Public Health Intervention with Water Treatment, Standard Public Health Intervention with Water Treatment & Hand Washing
- Where
- Bangladesh
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Childhood Cancer
Epigenetic and Metabolomic Changes in Childhood Cancer Survivors
The purpose of this research study is to try and identify markers in childhood cancer survivors to help predict if they will develop late effects from their cancer treatment.
- Trial name
- NCT03866707
- Testing
- One-time blood draw, Evaluation of CpG methylation, Metabolomic analysis
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Stunting, Malnutrition, Child
Effectiveness of SNF and SBCC to Prevent Stunting Among Children in Afghanistan: a Quasi-experimental Study
Over the years, there has been some progress made in reducing stunting in Afghanistan, the prevalence remains high with half of the provinces experiencing rates above the WHO alert threshold.
- Trial name
- NCT04581993
- Testing
- Super Cereal - wheat soya blend with sugar, Lipid-based nutrient supplement-medium quantity (LNS-MQ), Social and behavior change communication (SBCC)
- Where
- Afghanistan
- Volunteers
- 33,100 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Hyperthermia, Hypothermia
Testing A Visual Thermometer in Newborns and Young Infants
"Severe neonatal jaundice and acute bilirubin encephalopathy are a major cause of death and disability among newborns in LMICs. Filtered sunlight phototherapy (FSPT) was developed, tested and shown to be safe and efficacious in…
- Trial name
- NCT05609292
- Testing
- observational
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hodgkin Lymphoma
Therapy for Pediatric Hodgkin Lymphoma
With the success of current chemotherapy for Hodgkin's disease, the goal of this protocol is to maintain the currently successful cure rate and reduce treatment related side effects and long term toxicity.
- Trial name
- NCT00145600
- Testing
- 12 Week Stanford V Chemotherapy, 4 cycles of VAMP chemotherapy, 2 alternating cycles of VAMP/COP chemotherapy
- Where
- 5 sites in United States
- Volunteers
- 296 people
- Sponsor
- St. Jude Children's Research Hospital
Overweight and Obesity, Attention-Deficit Hyperactivity Disorder
Families, Responsibility, Education, Support, and Health for Executive Function
The pilot study will be a one group open-label treatment program and will be used to refine a parent-based behavioral treatment enhanced with executive-function training (PBT-EF) for children with comorbid overweight or obesity…
- Trial name
- FRESH-EF (NCT05165511)
- Testing
- PBT-EF
- Where
- United States
- Sponsor
- University of California, San Diego
Febrile Neutropenia
Risk Factors & Outcomes for Clinically Documented Infections in Pediatric Cancer Patients With Fever & Neutropenia
The aim of the study is to identify clinical and laboratory parameters, present at the time of initial evaluation that could help predict which children with cancer, fever, and neutropenia will be at risk for developing…
- Trial name
- NCT02536599
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Assiut University
Nephrosis, Focal Lipoid Glomerulosclerosis
Steroid Treatment for Kidney Disease
Focal segmental glomerulosclerosis (FSGS) and minimal change disease are kidney diseases that are associated with increased excretion of protein in the urine.
- Trial name
- NCT00065611
- Testing
- Oral dexamethasone
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Laparoscopic Abdominal Surgeries, Erector Spinae Plane Block
Erector Spinae Plane Block Versus Modified Thoracoabdominal Nerve Block for Analgesia in Pediatric Laparoscopic Abdominal Surgeries
Laparoscopic abdominal surgeries are frequently performed in pediatric patients and are often associated with significant postoperative pain, which, if inadequately managed, may delay recovery and increase the risk of chronic…
- Conditions
- Laparoscopic Abdominal Surgeries, Erector Spinae Plane Block, Modified Thoracoabdominal Nerve Block (M-TAPA)
- Trial name
- NCT07240064
- Testing
- Erector Spinae Plane Block, Modified thoracoabdominal plane block
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fever
Acetaminophen Before Vaccines for Infants Study (AVIS)
The purpose of this study is to see whether giving acetaminophen (the medicine in Tylenol) for routine infant vaccinations is helpful in preventing fever or other symptoms.
- Trial name
- NCT00325819
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Behavioral Changes
The Effect of an Emancipatory Knowing-Based Training Program on the Carbon Footprint of Postpartum Nursing Care
This study aims to examine the effect of a training program based on Emancipatory Knowing on nurses' awareness and practices related to carbon footprint reduction in postpartum nursing care.
- Trial name
- NCT07473219
- Testing
- PEACE+G Model-Based Emancipatory Knowing Training Program
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Hypoxic Ischaemic Encephalopathy
Xenon and Cooling Therapy in Babies at High Risk of Brain Injury Following Poor Condition at Birth
This study examines the effect of inhaled xenon gas in the treatment of newborn infants with hypoxic-ischemic encephalopathy (HIE) in combination with cooling, which is the standard treatment for this condition.
- Trial name
- CoolXenon2 (NCT01545271)
- Testing
- xenon gas, Whole body cooling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Hydration, Dehydration
Multimedia Hydration Education During Physical Education in Schoolchildren
Here's a plain-language Brief Summary ready to paste - it follows the PRS lay-language style (short sentences, explains the "why," avoids jargon) and fits well within 5,000 characters: Staying well hydrated helps children stay…
- Conditions
- Hydration, Dehydration, Health Behavior, Drinking Behavior
- Trial name
- NCT07669909
- Testing
- Multimedia hydration education programme
- Where
- 2 sites in Tunisia
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Child Obesity
Efficacy of Nuts in Obese Children.
Obesity is a problem of ever-growing importance, especially in industrialized countries, both in adults and in the pediatric population.
- Trial name
- NCT03870984
- Testing
- wNUTS, low-caloric diet plus nuts, w/oNUTS, low-caloric diet without nuts
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Fever
Prospective Trial for Clinical Validation of "QOCA Disposable BLE Thermometer "
The purpose of this trial is to evaluate the accuracy and safety of the "QOCA Disposable Body Temperature Patch" (Q-temp-w1).
- Trial name
- NCT05014152
- Testing
- Q-temp-w1, Omron thermometer(MC-171W)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
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