Clinical trials: Modification
Obesity, Overweight
Bariatric Outcomes Longitudinal Database (BOLD)
The primary purpose of the Bariatric Outcomes Longitudinal Database (BOLD) study is to assess the mid- and long-term outcomes of bariatric surgeries and to analyze the relationship between these outcomes and 1) patient…
- Conditions
- Obesity, Overweight, Diabetes
- Trial name
- BOLD (NCT01002352)
- Where
- United States
- Volunteers
- 600,000 people
- Sponsor
- Surgical Review Corporation
Pit and Fissure Sealants
Clinical Evaluation of Pit and Fissure Sealants
Pit and fissure sealants are considered an effective preventive approach in protecting teeth from caries, particularly by transforming deep, plaque-retentive occlusal surfaces into smooth, easily cleanable areas.
- Trial name
- NCT06987955
- Testing
- Biocoat Pit and fissure sealant, Fissurit FX Pit and fissure sealant
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Canan Bayraktar Nahir
Pediatric Obesity, Knowledge, Attitudes, Practice
iGrow Readers Nutrition and Physical Activity Curriculum Efficacy
The objective of this study was to determine the efficacy of the iGrow Readers curriculum in changing diet and physical activity knowledge among preschool-aged children.
- Conditions
- Pediatric Obesity, Knowledge, Attitudes, Practice, Physical Activity, Diet Modification
- Trial name
- NCT03668678
- Testing
- iGrow Readers Curriculum
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Epilepsy Intractable
Comparison of the Effectiveness of the Outpatient Classical Ketogenic Diet and Modified Atkins Diet on Seizures Frequency, Nutritional Status and Some Biochemical Factors in Children and Adolescents With Intractable Epilepsy
Epilepsy is one of a common neurological disorder. Antiepileptic drugs (AEDs) are usually the primary treatment of epilepsy. However, almost 30% of patients do not respond to AEDs and other treatments including ketogenic diet…
- Trial name
- NCT03014752
- Testing
- Classical ketogenic diet, Modified Atkins diet
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Tehran University of Medical Sciences
Cancer
Effect of Gender on Distress and Fatigue in Cancer Patients
Distress in cancer patients has been shown to be higher in females than males, but the behavior of distress during time in longitudinal prospective studies has not been studied, nor is it known if there are differences related to…
- Trial name
- NCT05122052
- Testing
- Psychological session
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Child Obesity
Efficacy of Nuts in Obese Children.
Obesity is a problem of ever-growing importance, especially in industrialized countries, both in adults and in the pediatric population.
- Trial name
- NCT03870984
- Testing
- wNUTS, low-caloric diet plus nuts, w/oNUTS, low-caloric diet without nuts
- Where
- Italy
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Modified Fixed Bridge
3D Printed vs CAD/CAM Rehabilitation of Primary Anterior Teeth Loss
compare 3D Printed versus CAD/CAM fabricated modified fixed appliance for rehabilitation of premature loss of anterior teeth in preschool children
- Trial name
- NCT07752147
- Testing
- 3D Printed modified fixed bridge, CAD/CAM fabricated modified fixed bridge
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Children Under General Anesthesia
Study on Changes of Pulse Oximeter Plethysmographic Amplitude Induced by Respiration in Pediatric Patients
The purpose of this study is to evaluate the variations of respiratory changes in pulse oximeter plethysmographic amplitude (delta POP) according to different contact forces between finger and sensor of pulse oximeter.
- Trial name
- NCT02940938
- Testing
- Applying pulse oximeter sensor
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Optic Neuritis
Effect of Vitamin D on Retinal Changes in Patient With Optic Neuritis by Optic Coherence Tomography
This study examines the effect of vitamin D on Retinal changes in patient with optic Neuritis.
- Trial name
- NCT01465893
- Testing
- Vitamin D, Vitamin D withheld
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Isfahan University of Medical Sciences
HIV Infection
Enhancement of Connect to Protect® (C2P)
The proposed study seeks to continue Connect to Protect® (C2P) community mobilization efforts that have developed coalitions that plan for and bring about structural changes for purposes of reducing HIV incidence and prevalence…
- Trial name
- NCT01492816
- Testing
- Community Mobilization
- Where
- 9 sites in United States
- Volunteers
- 927 people
- Sponsor
- University of North Carolina, Chapel Hill
Bronchiolitis
Vitamin D Supplementation for Acute Bronchiolitis
This study was conducted to evaluate the effect of oral vitamin D supplementation on the clinical course of acute bronchiolitis, and to investigate whether vitamin D deficiency among infants who required hospital-based care for…
- Trial name
- NCT03799406
- Testing
- Cholecalciferol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Tobacco Use
Address Tobacco Use Among Adolescents in Hong Kong
This study will examine the effectiveness of a social norms campaign in correcting smoking misperceptions, reducing smoking susceptibility and changing smoking-related behaviours in Hong Kong adolescents.
- Trial name
- NCT03264144
- Testing
- Social norms campaign
- Where
- Hong Kong
- Volunteers
- 12,868 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cerebral Palsy, Sleep Disorders in Children
Sleep Quality and Caregiver Burden in Children With Cerebral Palsy
Cerebral palsy (CP) is a lifelong condition affecting movement and posture, often requiring substantial care from family members.
- Conditions
- Cerebral Palsy, Sleep Disorders in Children, Caregiver Burden, Sleep Quality
- Trial name
- CP-SLEEP (NCT07168577)
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Selim Sezikli
General Anesthesia-Induced Altered Consciousness
Brain Activity and Changes in Consciousness During General Anesthesia
This study aims to investigate how general anesthetics alter brain activity and consciousness across different age groups. The study will evaluate four anesthetic agents with different mechanisms of action: propofol, remimazolam…
- Trial name
- NCT07836205
- Testing
- Propofol (Group P), Remimazolam group, Esketamine group
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Obesity, Weight Loss
Hormonal Regulation of Body Weight Maintenance
The investigators here propose to perform a collaborative clinical research effort including a randomized controlled trial investigating the mechanisms of weight maintenance and their relation to a lifestyle intervention in…
- Conditions
- Obesity, Weight Loss, Weight Gain, Hormone Disturbance
- Trial name
- NCT00850629
- Testing
- multimodal lifestyle intervention
- Where
- Germany
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Orthodontic Patients
Efficacy of Skeletally Anchored Modified Leaf Expander in Maxillary Molar Distalization
Background: Distalization in orthodontics is one of conservative treatment modalities that result in gaining space especially in dental orthodontic cases of class ΙΙ molar relationship.
- Trial name
- NCT07534072
- Testing
- skeletally anchored Modified Leaf Expander
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Single Ventricle Defect
Cerebral Blood Flow in Single Ventricles Throughout Staged Surgical Reconstruction
This study seeks to determine cerebral blood flow changes in single ventricle patients during staged surgical reconstruction as compared with normal children.
- Trial name
- CBF (NCT02135081)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Children's Hospital of Philadelphia
Diabetes, Gestational, Dietary Modification
Dietary Management of Gestational Diabetes in Obese Pregnant Women
eMOM is a randomized, controlled trial to compare the effects of two different dietary interventions during pregnancy. The comparison is based on tissue glucose content (using continuous glucose monitoring system) in pregnant…
- Conditions
- Diabetes, Gestational, Dietary Modification, Tissue Glucose, Body Composition
- Trial name
- eMOM (NCT03542071)
- Testing
- Carbohydrate restricted diet, Plant-protein based diet
- Where
- Finland
- Volunteers
- 2 people
- Sponsor
- Helsinki University Central Hospital
Infants, Intensive Care Unit
Open Surgical, Modified Seldinger's and US Techniques for Jugular Central Line Insertion in Infants
The aim of this study was to compare the three approaches: open technique, modified Seldinger's technique and closed ultrasound-guided Central venous catheterization insertion for central line insertion in infancy as regards…
- Conditions
- Infants, Intensive Care Unit, Central Venous Catheterization
- Trial name
- NCT06862492
- Testing
- Open surgical cut down technique, Modified Seldinger's technique, Closed Ultrasound guided CVC insertion
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Tanta University
Taste Perception, Fixed Orthodontic Appliances
Taste Changes With Fixed Orthodontic Appliances
The aim of this research: 1. To analyze the possible influence of fixed orthodontic appliances on taste perception among patients undergoing conventional orthodontic treatment. 2.
- Trial name
- NCT06093256
- Testing
- Fixed orthodontic appliances
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
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