Clinical trials: Movement Disorders
Parkinson Disease
Tolerability of Sifrol® in Ambulatory Patients Suffering From Parkinson's Disease
Study to obtain information about the co-operation of the different physician-colleagues in the treatment of patients with Parkinson's disease, both in private practices and clinics and about the primary treatment strategies in…
- Trial name
- NCT02248207
- Testing
- Pramipexole
- Volunteers
- 1,293 people
- Sponsor
- Boehringer Ingelheim
Tourette's Syndrome, Tourette's Disorder
Psychosocial Intervention for Young Children With Chronic Tics
Analysis of data from the recently completed NIH Child Comprehensive Behavioral Intervention for Tics (CBIT) study found a manualized behavioral treatment approach strongly superior to psychoeducation/supportive therapy for…
- Conditions
- Tourette's Syndrome, Tourette's Disorder, Tourette's Disease, Tourette Disorder
- Trial name
- CBIT JR (NCT03042507)
- Testing
- Comprehensive Behavioral Intervention for Tics (CBIT)
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Cerebral Palsy, Hand Functions
The Hand Functions In Cerebral Palsy
The hand motor functions are very important in the daily life activities, educational, and social participation of children. Losing The hand motor functions limit these activities and participation.
- Trial name
- NCT05988944
- Testing
- TT+CIMT+VR, TT+CIMT, TT
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Uludag University
Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder)
The Effects of Muscle Characteristics on the Control of Shoulder Complex During Functional Movements
The movement control of shoulder joint relies not only on the glenohumeral joint, but also the critical contributions from scapulothoracic joint.
- Conditions
- Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder), Movement Disorders
- Trial name
- NCT04176692
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tzu Chi University
Functional Movement Disorders, Reproducibility of Results
Aspects of Validity of the Single Leg Squat Test: A Cohort Study of Female Soccer Players.
Movement screening tests to identify deficits or poor movement quality is commonly used in soccer and other sports to assess injury, to evaluate rehabilitation goals and return to sport after injury.
- Conditions
- Functional Movement Disorders, Reproducibility of Results, Sports Medicine
- Trial name
- NCT05289284
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Parkinson Disease, Virtual Reality
Upper Extremity Rehabilitation With Virtual Reality in Parkinson's Disease Patients
Upper extremities are the first part of the body to be affected by Parkinson's disease. Although studies have shown that virtual reality-assisted rehabilitation methods are effective on gait and balance, studies on their use for…
- Conditions
- Parkinson Disease, Virtual Reality, Neurological Rehabilitation, Upper Extremity Dysfunction
- Trial name
- NCT06147726
- Testing
- Upper extremity position matching exercises in virtual reality, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ramazan KURUL
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Huntington Disease, Huntington's Disease
REGISTRY - an Observational Study of the European Huntington's Disease Network (EHDN)
This is a multi-centre, multi-national, prospective, observational study of Huntington's disease (HD) with a control group of volunteers to: obtain natural history data on many HD mutation carriers and individuals who are part of…
- Trial name
- REGISTRY (NCT01590589)
- Where
- 140 sites in Austria, Belgium and 15 more
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- European Huntington's Disease Network
Parkinson Disease
Intravenous Levodopa for the Diagnosis of Parkinson's Disease
Patients with Parkinson's disease have low levels of the neurotransmitter dopamine. Dopamine is responsible for motor function and normal physical activity.
- Trial name
- NCT00001928
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease
Talampanel to Treat Parkinson's Disease
This study will evaluate the effects of the experimental drug talampanel on dyskinesias (involuntary movements) that develop in patients with Parkinson's disease as a result of long-term treatment with levodopa (Sinemet).
- Trial name
- NCT00108667
- Testing
- IV Levodopa, Talampanel
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
PARKINSON DISEASE (Disorder), Parkinson Disease (PD), Postural Balance
Telerehabilitation Versus Face-to-Face LSVT BIG in Individuals With Parkinson Disease
This prospective, randomized controlled trial will enroll 40 individuals with idiopathic PD (Hoehn \& Yahr stages 1-3, MoCA ≥21).
- Conditions
- PARKINSON DISEASE (Disorder), Parkinson Disease (PD), Postural Balance, Parkinson Disease
- Trial name
- NCT07630792
- Testing
- Face-to-Face LSVT BIG, Telerehabilitation LSVT BIG
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Hemiplegia
Constraint Induced Movement Therapy on Infantile Hemiplegia
The purpose of this study is to assess the functionality of the affected upper limb in infantile hemiplegia by applying a protocol of modified constraint-induced movement therapy.
- Trial name
- NCT02178371
- Testing
- mCIMT, Unimanual therapy without constraint UTWC
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- CEU San Pablo University
Tourette Syndrome, Chronic Tic Disorders
Developing Cognitive Training for Tourette Syndrome
Many researchers suspect that individuals with Tourette Syndrome (TS) may have a poor cognitive ability (i.e., response inhibition; RI) that is essential to inhibit inappropriate response such as vocal or motor tics.
- Trial name
- NCT01440023
- Testing
- Comprehensive Behavioral Intervention for Tics (CBIT), Computerized Response Inhibition Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Milwaukee
Cerebral Palsy, Dystonia
Surface EMG Biofeedback for Children With Cerebral Palsy
Movement disorders such as dystonia, hypertonia, and spasticity interfere with or prevent voluntary movement. Studies have suggested that using biofeedback to increase awareness of muscle activation can improve motor function in…
- Conditions
- Cerebral Palsy, Dystonia, Hypertonia, Spasticity
- Trial name
- NCT01681888
- Testing
- Sanger EMG Biofeedback Device
- Where
- United States
- Sponsor
- University of Southern California
Movement Disorder, Learning Disability
Effects of a Task Oriented Intervention With Two Goal-setting Approaches
A randomized trial investigating if effects of a goal-directed task oriented intervention is influenced by who takes the decision and establishes the goal (the child or the parent) and whether establishing a goal per se influence…
- Conditions
- Movement Disorder, Learning Disability, Autism Spectrum Disorder, Children
- Trial name
- NCT02160886
- Testing
- child-goal, parent-goal
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Region Gävleborg
Parkinson Disease, Dystonia
Radiofrequency (RF) Ablation Prospective Outcomes Study for Central Nervous System - RAPID for CNS
The objective of this study is to compile real-world outcomes of Boston Scientific commercially approved radiofrequency (RF) ablation systems used in the central nervous system (CNS) for use in functional neurosurgery.
- Conditions
- Parkinson Disease, Dystonia, Essential Tremor, Movement Disorders
- Trial name
- NCT06553625
- Testing
- Radiofrequency Ablation
- Where
- 4 sites in Germany, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Boston Scientific Corporation
Huntington Disease
Wearable Sensors for Quantitative Assessment of Motor Impairment in Huntington's Disease Huntington's Disease
The principal means of measuring motor impairment in Huntington disease (HD) is the Unified Huntington's Disease Rating Scale (UHDRS) total motor score, which is subjective, categorical, requires significant training to…
- Trial name
- NCT03599076
- Testing
- HD Wear
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BioSensics
Parkinson's Disease, Parkinsonism
Parkinson's Families Project
One person in every 500 has Parkinson's and around 127,000 people are living with the condition in the UK. The aim of the study is to identify new genes that predispose or cause Parkinson's Disease or Parkinsonism.
- Trial name
- PFP (NCT02760108)
- Where
- 2 sites in United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Dystonia, Primary, Dysarthria
Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement…
- Conditions
- Dystonia, Primary, Dysarthria, Dysphonia, Dysphagia
- Trial name
- DOM (NCT03380676)
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
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