Clinical trials: Muscle Spasticity
Cerebral Palsy
Effect of TENS in Children With Spastic Cerebral Palsy
TENS is cheap and simple tool for physiotherapist, free of many side effects compared with other tools. so The aim of study was record the effect of TENS on calf muscle tone in spastic cerebral palsy children.
- Trial name
- NCT05649254
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Cairo University
Mollii Suit, Cerebral Palsy
Effects of Mollii Suit in Children With Non-Ambule Cerebral Palsy
The aim of our study is to examine the effectiveness of the Mollii Suit application on gross motor function, spasticity, postural control, upper extremity skills, selective motor control, daily living activities, quality of life…
- Trial name
- NCT06259864
- Testing
- EXOPULSE Mollii Suit method
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kırıkkale University
Recurrent Crying Spells
Recurrent Crying Spells in Cerebral Palsy
This is a study of recurrent crying spells in Spastic Cerebral Palsy patients and their treatment.
- Trial name
- RCSCPSQ (NCT01955655)
- Testing
- Baclofen
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sathbhavana Brain Clinic
Muscle Spasticity
Randomized Controlled Trial of Virtual Reality
Measure pain and anxiety during a putative painful medical procedure (i.e., botulinum toxin injections) when Virtual Reality is employed compared to standard of care only using a Randomized Controlled Trial study design.
- Trial name
- NCT03521076
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Gillette Children's Specialty Healthcare
Cerebral Palsy.
Exploring Hypertonia in Children With Cerebral Palsy
Abnormal limb and trunk movements are seen in many children with cerebral palsy. Recognizing the difference between types of these movements is not well understood.
- Trial name
- HypE-CP (NCT01744158)
- Testing
- No intervention applicable
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Women's and Children's Hospital, Australia
Cerebral Palsy
Which is the Best Dose of Dysport in Helping With Hip Pain for Children With Cerebral Palsy?
The purpose of the study is to compare the effectiveness of 3 doses of Dysport (5, 10 or 15 Units/Kg/hip) in the management of chronic bilateral hip pain due to cerebral palsy in children/young people.
- Trial name
- NCT00455637
- Testing
- Botulinum toxin type A
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Ipsen
Cerebral Palsy, Spasticity
Exopulse Mollii Suit, Motor Functions & CP Children With Cerebral Palsy
Cerebral Palsy (CP) is is estimated to be around 1.5-3 per live birth, with prenatal factors accounting for 75% of cases. CP appears in early childhood and persists with age and is characterized by permanent lesions or…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Pain Syndrome
- Trial name
- EXOCEP2GER (NCT05885139)
- Testing
- Exopulse Mollii Suit
- Where
- 2 sites in Germany
- Volunteers
- 34 people
- Sponsor
- Exoneural Network AB
Cerebral Palsy (CP), Unilateral Spastic Cerebral Palsy
Short-Term Effects of Manual Therapy Prior to Neuromotor Therapy in Children With Cerebral Palsy
This pilot study aims to evaluate the immediate, short-term biomechanical and neuromuscular effects of lower limb manual therapy applied as a preparatory phase prior to functional neuromotor rehabilitation in children with…
- Conditions
- Cerebral Palsy (CP), Unilateral Spastic Cerebral Palsy, Bilateral Spastic Cerebral Palsy, Diplegic Cerebral Palsy With Spasticity
- Trial name
- NCT07902466
- Testing
- Manual Therapy (T1 & T3)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- LIFE - Research and Care Institute - Santa Lucia IRCCS
Spasticity, Cerebral Palsy
Shockwaves Therapy and Botulinum Toxin for the Treatment of Spasticity in Patients With Cerebral Palsy. A Cross Over RCT
Spasticity is a motor disorder that can affect the lower limbs in up to 75% patients with cerebral palsy, having a significantly effect on their mobility and quality of life.
- Trial name
- NCT02400619
- Testing
- shock waves, Botulinum Toxin Type A
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Xavi Vidal Novellas
Spastic Cerebral Palsy (sCP)
Virtual Reality Combined With Bobath Therapy for Spastic Cerebral Palsy
Spastic cerebral palsy is a common neurodevelopmental disorder characterized by increased muscle tone, impaired balance, and limitations in motor function, particularly in the lower limbs.
- Trial name
- VR-BOBATH-CP (NCT07392398)
- Testing
- Virtual Reality Combined With Bobath Therapy, Conventional Bobath Therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tongren Hongxin Kangxin Traditional Chinese Medicine Hospital, Guizhou Province
Post Traumatic Induced Spasticity
Selective Dorsal Rhizotomy as a Cost Effective and Safe Procedure as a Alternative to Intrathecal Baclofen Pump in Patients With Post Traumatic Spasticity
The investigators will investigate the selective dorsal rhizotomy in post traumatic brain and spinal cord injury induced spasticity to evaluate the efficacy of this procedure in reducing the tone of the spastic muscle groups.
- Trial name
- NCT07583277
- Testing
- Selective dorsal rhizotomy with neuromonitoring
- Volunteers
- 32 people
- Sponsor
- Assiut University
Cerebral Palsy, Spastic Diplegia
MEOPA to Improve Physical Therapy Results After Multilevel Surgery
Children with cerebral palsy commonly undergo "multilevel surgery", meaning several lower limb combined procedures performed during the same surgical intervention.
- Conditions
- Cerebral Palsy, Spastic Diplegia, Quadriplegia, Hemiplegia
- Trial name
- KINOPA (NCT00632528)
- Testing
- MEOPA, Medicinal air
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Palsy
A Pilot Study of the Effect of Botulinum Toxin Type a (Dysport®, Abobotulinum Toxin A) Injection on Changes in Musculotendinous Length and Dynamics of Hamstring Muscles During Gait in Children With Spastic Cerebral Palsy Walking With Excessive Knee Flexion
This is a longitudinal, prospective, and open-label interventional study in a single center. We will investigate the effect of single injection in each patient.
- Trial name
- NCT02917967
- Testing
- Botulinum toxin injection
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Yonsei University
Cerebral Palsy (CP), Unilateral Cerebral Palsy
tDCS and Bi-manual Training in Cerebral Palsy
Unilateral spastic cerebral palsy (USCP) is the most common subtype of cerebral palsy and significantly limits upper limb function.
- Conditions
- Cerebral Palsy (CP), Unilateral Cerebral Palsy, Spastic Cerebral Palsy (sCP)
- Trial name
- NCT07573865
- Testing
- Anodal tDCS
- Where
- Pakistan
- Volunteers
- 15 people
- Sponsor
- Riphah International University
Cerebral Palsy
Effect of Dysport Injections on Energy Expenditure and Walking Efficiency in Children With Cerebral Palsy
This study aims to evaluate the efficacy of single event multi level chemoneurolysis with the abobotulinumtoxin A drug, Dysport®, on walking energy expenditure and gait in children with spastic diplegia cerebral palsy.
- Trial name
- NCT03469999
- Testing
- Dysport Injectable Product
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Cerebral Palsy
Effects of Play Based Neural Mobilisation Activities on Hand Grip Strength and Dexterity in Cerebral Palsy Children
The study design will be a Randomized control trial. The data will be collected from Acme Medical complex and Rehab cure clinic. The study will be completed in 10 months after the approval of synopsis.
- Trial name
- NCT07428928
- Testing
- neural mobilization which include ulnar, median and radial nerves mobilisation by a play activity called "Simon says" in addition to the routine physical therapy treatment., Regular physical therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Cerebral Palsy
Role of Kinesiotape Over Dorsi Flexors Muscles on Balance in Children With Spastic Diplegia
To detect the effect of kinesio -tape on balance in children with spastic diplegia.
- Trial name
- NCT04243928
- Testing
- kinesio taping
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy, Movement Disorders in Children
Reliability of Range of Movement Measurements in Cerebral Palsy
The aim is to investigate the inter-rater reliability of passive range of motion (pROM) measurement with goniometer of knee extension and ankle dorsiflexion for children with unilateral spastic cerebral palsy (USCP) and secondary…
- Trial name
- NCT06295107
- Testing
- Ankle Passive Range of Movement (pROM), Knee Passive Range of Movement (pROM)
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Spasticity, Muscle
Study of Brain-spinal Cord Neural Connectivity in Spasticity
Little is known about the peripheral and central mechanisms of action of selective dorsal rhizotomy surgery for the treatment of spasticity.
- Trial name
- MOVE (NCT06281223)
- Testing
- intraoperative neuroelectrophysiological monitoring
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cerebral Palsy
Orthosis to Improve Trunk Control in Infants Age 6-18 Months
The purpose of this study is to determine the impact of the SPIO® Core-MAX® Expedition orthosis on an infant's head, trunk and upper limb function.
- Trial name
- NCT06027580
- Testing
- SPIO® Core-MAX® Expedition thoracolumbosacral orthosis, Standard Care Therapy option
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical College of Wisconsin