Clinical trials: Near-infrared Spectroscopy
Neonates and Preterm Infants, Infant Respiratory Distress Syndrome
Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 Minutes
Respiratory distress syndrome (RDS) is common in very preterm infants due to surfactant deficiency. Surfactant replacement therapy is lifesaving, and current guidelines recommend the less invasive surfactant administration (LISA)…
- Conditions
- Neonates and Preterm Infants, Infant Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal, Surfactant
- Trial name
- SurfStab I (NCT07261787)
- Testing
- Poractant alfa (Curosurf®) - 1-minute administration, Poractant alfa (Curosurf®) - 5-minute administration
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Medical University of Graz
Intravenous Cannulation
The Effect of Near-infrared Spectroscopy on the Success of Peripheral Venous Access
The goal of this clinical trial is to learn if using near-infrared imaging in pediatric vein cannulation is leading to higher success rate.
- Trial name
- PEDVEIN (NCT07279701)
- Testing
- Use of near-infrared imaging by VeinViewer Flex of periferal veins
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Brno University Hospital
Hypoplastic Left Heart, Surgery
NIRS in Neonatal Cardiac Surgery
Due to the small size of infants and the use of bypass machines, physicians have difficulty assessing whether the infant's brain and body is getting enough oxygen during heart surgery.
- Trial name
- NCT00166101
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Patent Ductus Arteriosus
Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus
The purpose of this pilot trial is to study efficacy and safety of simultaneous intravenous (iv) ibuprofen/indomethacin and paracetamol medications in the closure of patent ductus arteriosus (PDA) in preterm infants.
- Trial name
- PAI (NCT03648437)
- Testing
- Paracetamol 10Mg/mL, 0.45% Sodium Chloride, Ibuprofen
- Where
- 4 sites in Finland
- Volunteers
- 22 people
- Sponsor
- University of Oulu
Traumatic Brain Injury, Intracranial Hypertension
Investigating CBF and ICP Using DCS
We aim to acquire data using DCS on patients who are undergoing invasive ICP and ABP monitoring on ITU as part of their normal treatment. Data will then be correlated to derive various parameters including CBF and BFI.
- Trial name
- ICP-CBF (NCT06039098)
- Testing
- DCS
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Queen Mary University of London
Near Infrared Spectroscopy
Cerebral Oximetry in Newborns - Comparing INVOS 5100 and FORE-SIGHT Cerebral Oximeters
Regional tissue oxygenation (rStO2) can be monitored by near infrared spectroscopy. The commercial devices FORE-SIGHT (CASMED) and INVOS (COVIDIEN) will be used simultaneously to test for their relative sensitivity for low oxygen…
- Trial name
- NCT01665287
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Microcirculation
Microcirculatory Alteration by a Vascular Occlusion Test Using Near-infrared Spectroscopy in Pediatric Cardiac Surgery
Cardiopulmonary bypass cause microcirculatory alterations. Near infrared spectroscopic measurement of tissue oxygen saturation and vascular occlusion test are novel technologies for assessing the microcirculatory function of…
- Trial name
- NCT06191913
- Testing
- Near-infrared spectroscop
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Supracondylar Humerus Fracture
Pediatric Supracondylar Humerus Fracture NIRS Study
The purpose of this study is to use a device to compare the blood flow in the patient's injured arm to the patient's uninjured arm.
- Trial name
- NCT01808183
- Testing
- Near Infrared Spectroscopy Pads
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wake Forest University Health Sciences
Brain Injuries, Infant, Premature
SafeBoosC - a Phase II Trial
Background 25,000 infants are born extremely preterm every year in Europe. This group of infants carries a high risk of death and subsequent cerebral impairment for the infant, especially in the first 72 hours of life.
- Trial name
- SafeBoosC (NCT01590316)
- Testing
- Cerebral NIRS oximetry
- Where
- Denmark
- Volunteers
- 165 people
- Sponsor
- Gorm Greisen
Neurofeedback, Attention Deficit Hyperactivity Disorder (ADHD)
Near-infrared Spectroscopy Neurofeedback as a Treatment for Children With Attention Deficit Hyperactivity Disorder
To observe the clinical efficacy and mechanism of functional near-infrared spectroscopy imaging neurofeedback therapy for attention deficit and hyperactivity disorder.
- Trial name
- NCT04065906
- Testing
- NIRS neurofeedback, Methylphenidate or Tomoxetine
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Prematurity
Effect of Monitoring Devices on Healthcare Provider Performance During Neonatal Resuscitation
Babies born very early (at less than 32 weeks) usually need help to breath right at birth, also called neonatal resuscitation. Healthcare providers (HCPs) are specially trained to provide this help.
- Trial name
- NCT04521725
- Testing
- Respiratory Function Monitor (RFM), Cerebral Near-Infrared Spectroscopy (NIRS)
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of Alberta
Pre-Term, Persistent Ductus Arteriosus
Evaluation of the Brain and Renal Regional Oxygenation Using NIRS in Preterm Infants
This study evaluates the brain and renal oxygenation using near infrared spectroscopy in preterm infants with persistent ductus arteriosus
- Trial name
- NCT04295395
- Testing
- NONIN SenSmart model X-100 near- infrared spectrometer
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Vilnius University
Congenital Heart Disease, Neurodevelopmental Disorders
Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease
Infants with congenital heart disease (CHD) are at increased risk for delayed neurodevelopment. Multiple etiological explanations have been proposed, as there seems to be a multifactorial interplay of both prenatal and…
- Conditions
- Congenital Heart Disease, Neurodevelopmental Disorders, Electroencephalography, Near-Infrared Spectroscopy
- Trial name
- NICO (NCT06190210)
- Testing
- electroencephalography, Near-Infrared Spectroscopy, neuronal cell-free DNA
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Premature Birth
NIRS Levels of Infants in Neonatal Intensive Care
Aim: This study was conducted to determine the effect of nursing care practices on the Near Infrared Spectroscopy (NIRS) levels of premature infants in the neonatal intensive care unit (NICU).
- Trial name
- NCT05246150
- Testing
- nursing care practices
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Respiratory Distress Syndrome, Prematurity
The Effect of Surfactant Administration on Cerebral Oxygenation
The purpose of this study is to assess changes in cerebral oxygenation during two different types (beractant and poractant) and two different routes (double lumen or single lumen endotracheal tube) of surfactant administration…
- Trial name
- NCT01258517
- Testing
- near infrared spectroscopy (INVOS 5100)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Hearing Impaired Children
EarGenie MVP Performance Evaluation
This is a single-group clinical trial to evaluate the performance of the EarGenie minimum viable product (MVP) in normal hearing infants.
- Trial name
- NCT06406088
- Testing
- EarGenie MVP test
- Where
- Australia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Bionics Institute of Australia
Epilepsy
Electrohaemodynamic Activity in Epileptic Children : Combined Video-EEG and Near-infrared Spectroscopy (NIRS) Analysis
Evaluate the contribution of multimodal high-resolution EEG-NIRS electrical and local haemodynamic analysis to spatial localization of epileptogenic foci
- Trial name
- NIRS Epilepsie (NCT02814331)
- Testing
- multimodal high-resolution EEG-NIRS
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Single-ventricle
Association of Near Infrared Spectroscopy With Interstage Outcomes
The purpose of this study is to assess the utility of renal near infrared spectroscopy in the outpatient setting during the interstage period.
- Trial name
- NCT06538571
- Testing
- Near infrared spectroscopy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Advocate Hospital System
Anesthesia, Pain
Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia
The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to…
- Trial name
- NCT02703090
- Testing
- Remifentanil, Normal saline
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston Children's Hospital
Cerebral Oxygenation
Cerebral Tissue Oxygenation Values in Newborns Measured Using Laser and LED NIRS Oximeters
The aim of the study is to compare the values of cerebral tissue oxygenation measured simultaneously using laser light (FORE-SIGHT) and LED (INVOS) cerebral oximeters.
- Trial name
- NCT01496027
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences