Clinical trials: Necrosis
Necrotic Pulp
Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates
Injectable platelet-rich fibrin (I-PRF) is a flowable blood concentrate that is entirely natural and allows ease of access and flow within the root canal. It was first developed in 2014 by modifying the centrifugation parameters.
- Trial name
- NCT03698188
- Testing
- Injectable platelet-rich fibrin, Platelet-rich plasma
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myocardial Infarction, Compliance Behavior
The Music Activity INTervention for Adherence Improvement Through Neurological Entrainment
Auditory motor-coupling has been shown to induce neural-entrainment that can synchronize walking-pace with sonic tempo. The extent to which acoustical-motor entrainment can induce longer-term changes to physical activity…
- Conditions
- Myocardial Infarction, Compliance Behavior, Patient Compliance
- Trial name
- MAINTAIN (NCT01752595)
- Testing
- Preference Based Rhythmic Auditory Stimulation Music, Preference Based Music Intervention
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- Toronto Rehabilitation Institute
Dental Pulp Necroses, Tooth, Nonvital
Antimicrobial Photodynamic Therapy in the Endodontic Treatment of Anterior Primary Teeth With Pulp Necrosis
This randomized controlled clinical trial evaluated the immediate reduction in intracanal microbial load and the short-term clinical and radiographic progression of anterior primary teeth with pulp necrosis after conventional…
- Trial name
- NCT02485210
- Testing
- Conventional Endodontic Treatment, Antimicrobial Photodynamic Therapy
- Where
- Brazil
- Volunteers
- 7 people
- Sponsor
- University of Nove de Julho
Cardiovascular Diseases, Myocardial Infarction
Effect of Drug Therapy on Reinfarction Risk in Women
To evaluate the safety of calcium-channel blockers in the secondary prevention of myocardial infarction in women.
- Conditions
- Cardiovascular Diseases, Myocardial Infarction, Heart Diseases
- Trial name
- NCT00005389
- Sponsor
- University of Washington
Sepsis, Cancer, Heart Attack, Heart Failure, Abdominal Surgery, Trauma, Diabetes, Lung Disease, Gynaecology, Fertility, Cardiac Surgery,
Medical Record Study on Adverse Events Requiring a Higher Level of Care in Flemish Hospitals
An adverse event (AE) is defined as unintended injury or complication, which results in disability, death or prolongation of hospital stay, and is caused by healthcare management (including omissions) rather than the patient's…
- Trial name
- NCT02044718
- Where
- Belgium
- Volunteers
- 878 people
- Sponsor
- Hasselt University
Diabetes Mellitus, Non-insulin Dependent, Cardiovascular Diseases
Heavy Metals, Obesity and Cardiovascular Risk - Ancillary to Look AHEAD
To evaluate the relationship of baseline toenail chromium concentrations to weight loss, as well as the interaction between heavy metals and the beneficial effects of weight loss.
- Conditions
- Diabetes Mellitus, Non-insulin Dependent, Cardiovascular Diseases, Obesity, Myocardial Infarction
- Trial name
- NCT00031213
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Myocardial Infarction
Acute Myocardial Infarction by Penetrating Cardiac Trauma
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly…
- Trial name
- NCT01182064
- Where
- Colombia
- Volunteers
- 51 people
- Sponsor
- Universidad de Antioquia
Cardiovascular Diseases, Heart Diseases
Epidemiology of Coronary Heart Disease in Blacks
To conduct an analysis of the epidemiology of coronary heart disease (CHD) in Blacks using data collected from the 'Survival and Ventricular Enlargement (SAVE) Following Myocardial Infarction' study.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005410
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Osteonecrosis
The British Osteonecrosis Study
The aim of this research is to examine the natural history of osteonecrosis in older children, teenagers and young adults with acute lymphoblastic leukaemia and lymphoblastic lymphoma within the UK.
- Trial name
- BONES (NCT02598401)
- Testing
- observation
- Where
- 4 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Leeds
Osteoarthritis, Dislocations
Epidemiology and Outcomes of Upper Limb Surgery: Analysis of Routine Data
Surgery is a common treatment type for damaged joints, tendons and nerves in the upper limb where conservative measures are inappropriate or have failed.
- Conditions
- Osteoarthritis, Dislocations, Inflammatory Arthritis, Rotator Cuff Tear
- Trial name
- NCT03573765
- Testing
- Shoulder arthroplasty, Elbow arthroplasty, Hand and wrist arthroplasty
- Volunteers
- 8,308,821 people
- Sponsor
- University of Oxford
Pulp Necrosis, Irreversible Pulpitis
CLINICAL AND RADIOGRAPHIC SUCCESS OF MODIFIED LSTR TECHNIQUES IN PRIMARY SECOND MOLARS
This study aimed to evaluate and compare the clinical and radiographic success of different antibiotic and vehicle modifications of the Lesion Sterilization and Tissue Repair (LSTR) technique in infected mandibular primary second…
- Trial name
- NCT07836686
- Testing
- 3Mix-MP Antibiotic Paste, 3Mix-NS Antibiotic Paste, 2Mix-MP Antibiotic Paste
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Uşak University
Myocardial Infarction
Early Percutaneous Coronary Intervention (PCI) After Fibrinolysis Versus Standard Therapy in ST Segment Elevation Myocardial Infarction (STEMI) Patients
Several recent trials (1,2) suggest that all STEMI patients receiving fibrinolysis in non-PCI centres should be routinely transferred for elective early PCI within 24 hours from hospitalization, with no additive risk of major…
- Trial name
- NCT01014182
- Where
- United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Acute Coronary Syndrome
Secondary Prevention in Acute Coronary Syndromes: A CALIBER Study
All contemporary guidelines for secondary prevention in acute coronary syndromes recommend a combination of aspirin, beta-blockers, ACE-inhibitors and statins. Yet underutilisation of these drugs is common.
- Trial name
- NCT01162187
- Volunteers
- 400,000 people
- Sponsor
- University College, London
Pancreatic Pseudocyst Infection, Pancreatic Pseudocyst
Hot AXIOS System Japan Post Market Survey
To detect information of Adverse Events and Device Malfunctions under real world medical condition in Japan.
- Conditions
- Pancreatic Pseudocyst Infection, Pancreatic Pseudocyst, Walled Off Necrosis Infection, Walled Off Necrosis
- Trial name
- NCT03797209
- Testing
- EUS-guided fistulization AXIOS
- Where
- 40 sites in Japan
- Volunteers
- 120 people
- Sponsor
- Boston Scientific Japan K.K.
Necrotic Primary Molars
3Mixtatin Versus Modified 3Mix-MP in Lesion Sterilization and Tissue Repair for Treatment of Necrotic Primary Molars
This randomized clinical study aims to assess the clinical and radiographic success rate of the 3Mixtatin versus the 3Mix in LSTR in necrotic primary molars.
- Trial name
- LSTR (NCT05677945)
- Testing
- 3Mixtatin paste: Simvastatin mixed with modified triple antibiotic, 3Mix: Modified triple antibiotic mix in propylene glycol
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pancreatic Necrosis
Predicting Pancreatic Necrosis Using mitDNA
Multiple predictors have been used for early pancreatic necrosis, prediction, detection, and monitoring. These include clinical score systems and circulating biomarkers.
- Trial name
- NCT03788928
- Testing
- serum mitochondrial DNA
- Volunteers
- 25 people
- Sponsor
- Assiut University
Revascularization
Regeneration of Immature Teeth. Case Series
This clinical study aims to investigate the predictability of revascularization procedure of immature necrotic human permanent teeth with apical periodontitis.
- Trial name
- NCT03507556
- Testing
- Triple paste and induced bleeding, Triple Paste metronidazole, ciprofloxacin and minocycline mixed with sterile glycol
- Where
- Jordan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Necrotic Pulp
Chitosan,Chitosan Nanoparticles,and Chlorhexidine Gluconate, as Intra Canal Medicaments in Primary Teeth
Aim of the present study is to assess the in vivo susceptibility of root canal bacteria to Chitosan,Chitosan nanoparticles ,and Chlorhexidine gluconate when used as intra canal medicaments in necrotic primary molars
- Trial name
- NCT03588351
- Testing
- chitosan nanoparticles gel, chitosan gel, chlorhexidine gluconate
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Stable Angina, Myocardial Infarction
Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease
The Cardiovascular disease research using Linked Bespoke studies and Electronic Records (CALIBER) e-health database was the data resource for this study.
- Conditions
- Stable Angina, Myocardial Infarction, Coronary Heart Disease, Heart Failure
- Trial name
- NCT02244853
- Where
- United Kingdom
- Volunteers
- 51,703 people, healthy volunteers welcome
- Sponsor
- University College, London
Graft Versus Host Disease, Acute, Hematopoietic Stem Cell Transplantation
Infliximab Efficacy, TDM and Serum TNFα Levels in Pediatric HSCT Recipients With aGVHD: Prospective Observational Study
In children receiving a hematopoietic stem cell transplant (HSCT), blood levels of TNFalpha (an inflammatory cytokine) at the onset of the acute GVHD (graft-versus-host disease) could be correlated with the severity of the…
- Trial name
- NCT05362630
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- University of Pisa