Clinical trials: Neonatology
Neonatal Hypoglycemia
Comparing Heel Stick Glucoses in Neonates
Newborn babies can develop low blood sugar (glucose) which can lead to brain injury and poor developmental outcomes. Therefore, it is important to accurately measure the blood glucose in babies.
- Trial name
- CHECK IN (NCT04811612)
- Testing
- Warmed heel stick
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Sepsis, Neonatal
Comparison Between Split Septum and Mechanical Valve Needleless Connector in Preterm Babies
The goal of this clinical trial study is to compare the effectiveness between split septum and mechanical valve needleless connector in very preterm babies (or under 1500 grams) The main questions it aims to answer are: What is…
- Trial name
- NCT06414174
- Testing
- Split septum needleless connector, Mechanical valve needleless connector
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Necrotizing Enterocolitis
Identification of Clostridium Butyricum and Clostridium Neonatal in the Digestive Microbiota of Premature Infants Before 34 Weeks and Developing or Not Ulcerative Necrotizing Enterocolitis (NEC) During Hospitalization
The study investigators hypothesize that Clostridium butyricum and Clostridium neonatal will be more frequently found in the stool of preterm infants with ulcerative necrotizing enterocolitis compared to healthy matched control…
- Trial name
- ECUN-2 (NCT04584320)
- Testing
- Stool sample
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Jaundice, Neonatal, Neonatal Diseases and Abnormalities
Evaluation of Bili-ruler, a Low-cost, Plastic Icterometer for Community-based Screening of Jaundice in Newborns
Newborn jaundice, or accumulation of bilirubin molecules in blood, affects 60-80% of newborns and, in severe cases, places newborns at risk of brain damage and death.
- Conditions
- Jaundice, Neonatal, Neonatal Diseases and Abnormalities, Neonatal Hyperbilirubinemia, Screening Tool
- Trial name
- NCT06687746
- Testing
- Bili-ruler
- Where
- 5 sites in India, Kenya and 2 more
- Volunteers
- 4,060 people, healthy volunteers welcome
- Sponsor
- George Washington University
Prematurity
Early Exposure to OMT Prevents Long LOS
The application of osteopathic manipulative treatment (OMT) in preterm infants has been demonstrated to be effective in reducing length of stay (LOS).
- Trial name
- NCT01784835
- Testing
- osteopathic manipulative treatment, Usual care
- Where
- Italy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Diarrhea, Dehydration
Clinical Evaluation of Ultrasonic Hydration Monitor for Infants
Study will verify ability of infant Hydration Monitor (IHM) to assess changes of hydration status in newborns and infants by means of ultrasound velocity measurements through muscle tissues.
- Trial name
- IHM-01 (NCT01482208)
- Where
- Latvia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories
Pain Score
Prevention of Pain Caused by the Oro-gastric Tube Laying in Neonatology
Subject of research : Evaluation of a technique of care to reduce the pain caused by the laying of the gastric tube in the newborn
- Trial name
- DOLATSONG (NCT03142230)
- Testing
- the laying of the gastric tube and a group using the holed baby bottle nipple, the feeding tube ideally positioned at the center of the intersection pharyngeal, the laying of the gastric tube and a group with simple non-nutritive suction, the feeding tube passing next to the newborn's personal pacifier
- Where
- 3 sites in France
- Volunteers
- 71 people
- Sponsor
- Centre Hospitalier Sud Francilien
Critical Illness, Echocardiography
Impact of Echocardiography on Management of Critically Ill Neonates
The goal of the study was to estimate the outcome (mortality and morbidity) among hemodynamically unstable neonates, as well as the time to return to hemodynamic stability following the use of ECHO in the management of…
- Conditions
- Critical Illness, Echocardiography, Neonatology
- Trial name
- NCT06533787
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sahar Abozkaly Mahmoud
Newborn, Vision, Ocular
Masks and Visual Preferences in the Newborn
What impact can facial masks have on face exploration in the first few weeks of life? No study has yet investigated this. The objective of our study was to evaluate the impact of the mask on the face processing (preferential…
- Conditions
- Newborn, Vision, Ocular, Masks
- Trial name
- BABYMASK (NCT05109481)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Retinopathy of Prematurity
Oral Propranolol Improve Retinopathy of Prematurity Outcomes in Very Preterm Infants
Retinopathy of prematurity (ROP) is a major cause of blindness and visual impairment in children in both developing and developed countries around the world.
- Trial name
- NCT02977000
- Testing
- Propranolol
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Huiqing Sun
Premature Infant, Hypoxia
Measuring Oxygenation of Newborn Infants in Targeted Oxygen Ranges
The investigators aim to measure the effect of targeting premature babies to a slightly higher oxygen saturation target range (92-97%) than routinely used, for a brief period, to plan a future larger study of the effect of this…
- Conditions
- Premature Infant, Hypoxia, Hyperoxia
- Trial name
- MONITOR (NCT03360292)
- Testing
- Higher target range
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Neonatal Critical Care
Palliative Care in Maternity and Neonatology
Palliative care is now an accepted principle in most maternity and neonatology wards, however not much is known about its psychological and social consequences on families.
- Trial name
- VESPAN (NCT04619901)
- Testing
- Semi-structured interviews, Questionnaire, following Scales
- Where
- 4 sites in France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Lille
Premature Birth
Studying Newborns' Brain Activity in the NICU Through a Musical Intervention: the Role of Fundamental Frequency
This research project stands to the intersection of neonatology, neuroscience, and music based interventions (MBIs), exploring the impact of structured sound on the brain activity of premature newborns in Neonatal Intensive Care…
- Trial name
- FunFreqNICU (NCT06398912)
- Testing
- Music Based Intervention
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Bacteriology
Dynamic of the Acquisition of Antibiotic Resistance in Integrons in Neonatology Newborns
Antibiotic resistance is a major public health issue as multiresistant bacteria (MRB) are increasing. Among the actions to control resistance, one is an interesting lead: to prevent the emergence of resistant bacteria by limiting…
- Trial name
- DAIR3N (NCT02434679)
- Where
- 5 sites in France
- Volunteers
- 278 people
- Sponsor
- University Hospital, Limoges
Premature Birth
Developmental Care Program in Neonatal Intensive Care Unit
This project is a Randomised Clinical Trial that includes a family centred education intervention and/or non-directive active listening counselling intervention with families of preterm infants at risk for sensori-motor disorders.
- Trial name
- CIN (NCT05573945)
- Testing
- Family Education and Active Listening, Family Education
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Pisa
Infant of Diabetic Mother
Infants of Diabetic Mothers in Neonatology Unit at Assiut University Children's Hospital
Determine spectrum of clinical presentations and complications associated with maternal diabetes mellitus in their newborns attending and admitted to Neonatal Intensive Care Unit of Assiut University Children's Hospital.
- Trial name
- NCT06111157
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Premature Birth
Involving Family Stakeholders in the NICU: a New Perspective to Improve Quality of Life. PAREN
Introduction Thanks to medical advances in neonatal care, the majority of children admitted to the neonatal intensive care unit (NICU) survive and enjoy a good quality of life.
- Trial name
- PAREN (NCT06811064)
- Testing
- Testimony video
- Where
- France
- Volunteers
- 1,008 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Hemodynamic Instability
An Optical Neuro-monitor of Cerebral Oxygen Metabolism and Blood Flow for Neonatology
Feasibility trial on the use of a hybrid optical device integrating time-resolved near-infrared spectroscopy (TRS) and diffuse correlation spectroscopy (DCS) for measurement of cerebral oxygen metabolism and blood flow in…
- Trial name
- BabyLux (NCT02815618)
- Testing
- BabyLux Neuro-monitor
- Where
- 2 sites in Denmark, Italy
- Volunteers
- 48 people
- Sponsor
- Gorm Greisen
Neonates and Preterm Infants, Neonates or Premature Babies
Prospective Study of the Feasibility of Brain Connectivity Imaging by Functional Ultrasound Imaging (fUS) in Newborn Infant
Neurodevelopmental disorders (NDD) affect how the brain develops and can lead to lifelong difficulties with movement, learning, behavior, and thinking.
- Trial name
- CONEXUS (NCT06940713)
- Testing
- Imaging Time
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Oral History
History of Neonatology
This study traces the history of neonatology in the United States from the 1960s to the present with particular attention to the ways in which neonatologists developed criteria to make treatment decisions.
- Trial name
- NCT06176950
- Testing
- Oral History Interviews
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey