Clinical trials: Newborn, Transient
Transient; Hypoglycemia, Neonatal, Preterm
Oral Glibenclamide in Preterm Infants With Hyperglycaemia (GALOP)
The purpose of this study is to confirm hypothesis that Glibenclamide can be administered orally and is an alternative to insulin therapy in treating transient hyperglycemia of premature newborns.
- Conditions
- Transient; Hypoglycemia, Neonatal, Preterm, Glibenclamide Adverse Reaction
- Trial name
- GALOP (NCT05687500)
- Testing
- Glibenclamide, Pharmacokinetics study, C-peptide proinsulin ratio
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Compare Between the Serum Level of Lcarnitine in HIE Cases and TTN
Measuring Serum Level of Total L Carnitine in HIE and TTN
It is a comparative prospective and observational study conducted at Neonatal Intensive Care Unit (NICU) in Assiut University Children Hospital.
- Trial name
- HIELcarnitine (NCT04546321)
- Testing
- serum L carnitine level measuring
- Volunteers
- 47 people
- Sponsor
- Assiut University
Newborn Rds, Transient Tachypnea of the Newborn
LUNG ULTRASONOGRAPHY DECREASES RADIATION EXPOSURE
We aimed to decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography. From January 2019 to June 2020, 104 newborn infants with respiratory distress enrolled in this study.
- Conditions
- Newborn Rds, Transient Tachypnea of the Newborn, Pneumonia
- Trial name
- LUDRE (NCT04722016)
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Hacettepe University
Biliary Atresia, Alagille Syndrome
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)
Noninvasive monitoring of liver fibrosis is an unmet need within the clinical management of pediatric chronic liver disease. While liver biopsy is often used in the initial diagnostic evaluation, subsequent biopsies are rarely…
- Conditions
- Biliary Atresia, Alagille Syndrome, Alpha1 Anti-Trypsin Deficiency, Portal Hypertension
- Trial name
- FORCE (NCT02922751)
- Testing
- Liver Stiffness Measurement (LSM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 552 people
- Sponsor
- Arbor Research Collaborative for Health
Diastolic Dysfunction, Neonatal Encephalopathy
Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined…
- Conditions
- Diastolic Dysfunction, Neonatal Encephalopathy, Small for Gestational Age at Delivery, Transient Tachypnea of the Newborn
- Trial name
- DiFuSE (NCT06200519)
- Where
- Ireland
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University College Cork
Transient Hypothyroxinemia of Prematurity, Neurodevelopmental Abnormality
ASQ Scores of Transient Hypothyroxinemia of Prematurity
Transient hypothyroxinemia of prematurity (THoP) is defined as free thyroxine (FT4) level is below the reference values despite normal TSH level in preterm infant.
- Trial name
- NCT05901623
- Testing
- 'Ages and Stages Questionnaries' (ASQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Transient Tachypnea of the Newborn
Reducing Respiratory Distress After Elective Caesarean Birth Through Knee-chest-flexion: a Randomized Controlled Trial
Planned caesarean birth is a risk factor for the development of neonatal respiratory distress commonly known as transient tachypnoea of the newborn.
- Trial name
- NCT06270823
- Testing
- Knee-to-chest-flexion manoeuvre
- Where
- Tanzania
- Volunteers
- 562 people
- Sponsor
- Kilimanjaro Clinical Research Institute
Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn
The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term Infants
Sustained inflation (SI) has been reported to be effective for reducing the need for intubation and/or invasive ventilation in preterm infants.
- Conditions
- Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn, Respiratory Morbidity
- Trial name
- NCT03165305
- Testing
- Sustained Inflation
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Ultrasonic Diagnosis
Lung Ultrasound as a Predictor of Mechanical Ventilation in Neonates Older Than 32 Weeks
Neonatal respiratory distress prognosis may be difficult to estimate at admission. Lung ultrasound is a useful diagnostic tool that is quick, requires little training and is radiation free.
- Trial name
- NCT02449863
- Testing
- Lung ultrasound
- Where
- 2 sites in Spain
- Volunteers
- 105 people
- Sponsor
- Hospital Sant Joan de Deu
Cochlear Function
Interrelations Between Spontaneous Otoacoustic Emissions and Transient Evoked Emissions
To verify the occurrence of Spontaneous Otoacoustic Emissions (SOAE) in neonates at term and preterm infants who had transient otoacoustic emissions and verify if the presence of response is related to gestational age, gender or…
- Trial name
- NCT01325272
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Epigastric Pain, Retrosternal Pain
Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain
We would like to evaluate the changes in nerve innervation and TRPV1 receptor expression along with microscopic changes associated with heart burn and abdominal pain
- Conditions
- Epigastric Pain, Retrosternal Pain, Esophagitis, Gastrointestinal Symptoms
- Trial name
- TRPV1 (NCT00677378)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Medical College of Wisconsin
Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant
Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting
The purpose of this study is to analyze the gastric fluid aspirated from the stomachs of neonates receiving routine post-delivery care to predict the need for prolonged respiratory support (>6 hours of life).
- Conditions
- Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant, Transient Tachypnea of the Newborn, Meconium Aspiration Syndrome
- Trial name
- NCT07344714
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pes Planus
Low Dye Taping Technique and Temporary Felt Insoles on Pain and Disability in Children With Pes Planus.
This study aims to determine comparative effects of low dye taping technique and temporary felt insoles on pain and disability in children with pes planus.
- Trial name
- NCT05764967
- Testing
- Low Dye Taping, Temporary Felt Insoles
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University