Clinical trials: Organophosphate Poisoning
Neurotoxicity Syndromes
Scopolamine Treatment for Patients With Organophosphate Poisoning
Organophosphate (OP) compounds are a major threat as chemical warfare agents or in terrorist act. OPs are also the active ingredient of many insecticides.
- Trial name
- NCT00389259
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Poisoning
Pesticide Exposure Pathways for Farmworker Children
This project is aimed at better understanding how children living in agricultural environments are exposed to pesticides, and how such exposures can be prevented or reduced.
- Trial name
- NCT00013754
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Organophosphate Poisoning
Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning
We hypothesize that salbutamol will speed removal of alveolar fluid compared to atropine alone in OP poisoned patients. We propose to compare the effect of two stat doses of nebulized salbutamol (2.5 mg; 5.0 mg), with nebulized…
- Trial name
- SalbutamolOP (NCT02160548)
- Testing
- Standard care, Standard care+ 2.5 mg Salbutamol, Standard care+ 5 mg Salbutamol
- Where
- Bangladesh
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sylhet M.A.G.Osmani Medical College
Organophosphorus Poisoning
Outcome of Moderate Severity in OPC Poisoning Patients When Treated With Pralidoxime
This open level randomized controlled trial will be conducted in the department of medicine at Sir Salimullah Medical College and Mitford Hospital.
- Trial name
- OPC (NCT06111352)
- Testing
- Pralidoxime, Atropine
- Where
- Bangladesh
- Volunteers
- 96 people
- Sponsor
- Sir Salimullah Medical College Mitford Hospital
Disorders of Environmental Origin
Reducing Pesticide Exposure in Minority Families
This is a community-based participatory research program focusing on pesticide contamination in migrant farmworker families.
- Trial name
- NCT00014807
- Testing
- Reducing Pesticide Exposure in Minority Families
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Organophosphate Poisoning
Paraoxonase-1 Pseudo Cholinesterase Organophosphate Toxicity Enzyme in Prediction the Severity and Outcome of Acute Organophosphate Poisoning and Its Correlation With Pseudo Cholinesterase Enzyme Level.
The aim of the present study is to: Evaluate the serum Paraoxonase-1 level in cases with organophosphate compounds poisoning and to correlate it᾿s level with the severity, outcome of acutely organophosphate poisoned cases .
- Trial name
- NCT06108557
- Testing
- Serum Pararoxonase -1 level, Diagnostic Test: Serum pseudocholinesterase enzyme level
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Organophosphate Poisoning
A Pilot Study Using Rocuronium to Prevent Intermediate Syndrome After Organophosphorus Insecticide Poisoning
Organophosphate pesticide poisoning causes close to 300 000 deaths per year worldwide. Many patients who ingest organophosphates require ventilation; of these patients approximately 50% die.
- Trial name
- NCT02147054
- Testing
- Rocuronium, Sugammadex
- Where
- Sri Lanka
- Volunteers
- 45 people
- Sponsor
- University of Edinburgh
Acute Organophosphorus Pesticide Poisoning
Study to Know the Efficacy of Higher Doses of Pralidoxime in Patients of Organophpsphorus Poisoning.
The purpose of this study is to determine whether high doses of pralidoxime(PAM) are effective as compare to lower doses of PAM in the management of moderately sever organophosphorus poisoning patients.
- Trial name
- NCT00333944
- Testing
- Pralidoxime(drug)
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Giriraj Hospital
Poisoning
Community Based Prevention/Control Project
This project is aimed at better understanding how children living in agricultural environments are exposed to pesticides, and how such exposures can be prevented or reduced.
- Trial name
- NCT00013767
- Testing
- Individual and Community education
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)