Clinical trials: Orthodontic Tooth Movement
Malocclusion, Corticotomy
Evaluation of Corticotomy-Assisted Canine Retraction Rate
The goal of this split-mouth randomized clinical trial is to evaluate the effectiveness of corticotomy on maxillary canine retraction rate compared to conventional orthodontic techniques.
- Conditions
- Malocclusion, Corticotomy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- BMU/2026/8506 (NCT07879066)
- Testing
- Experimental: Corticotomy¬-Assisted Canine Retraction, Active Comparator / Control: Conventional Canine Retraction
- Where
- Bangladesh
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Malocclusion, Angle Class II
Effects of Power Arm Application in Maxillary Canine Distalization
The aim of this study is to investigate the effects of a canine distalization force applied between power arms placed on the maxillary canine and first molar, in comparison with the classical method without power arms.
- Conditions
- Malocclusion, Angle Class II, Tooth Movement Techniques, Orthodontic Anchorage Procedures
- Trial name
- NCT07866976
- Testing
- Canine and molar power arms, Conventional canine retraction
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Atlas University
Malocclusion, Canine Retraction
Maxillary Canine Retraction Using Stainless Steel and Titanium-molybdenum Alloy Wires in TAD-supported Segmental Mechanics
The goal of this randomized clinical study is to compare the effectiveness of stainless steel (SS) and titanium-molybdenum alloy (TMA) wires for maxillary canine retraction using TAD-supported segmental mechanics.
- Conditions
- Malocclusion, Canine Retraction, Orthodontics, Tooth Movement Techniques
- Trial name
- NCT07645417
- Testing
- A titanium-molybdenum alloy reverse-closing loop, A stainless steel reverse closing loop
- Where
- Bangladesh
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Deep Bite Malocclusion, Intrusion of Tooth
Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations
Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.
- Conditions
- Deep Bite Malocclusion, Intrusion of Tooth, Orthodontic Tooth Movement, Root Resorption
- Trial name
- MOPs (NCT07566676)
- Testing
- Micro-osteoperforations, Utility arch
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University
Class I Malocclusion, Maxillary Prognathism
Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper Arch
study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.
- Conditions
- Class I Malocclusion, Maxillary Prognathism, Orthodontic Tooth Movement
- Trial name
- NCT07521267
- Testing
- Silver nanoparticles, uncoated titanium miniscrews
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Al-Azhar University
Orthodontic Tooth Movement
GCF Volume Changes in Aligners and Fixed Appliances
Orthodontic tooth movement induces biological responses in periodontal tissues that can be reflected by changes in gingival crevicular fluid (GCF).
- Trial name
- GCF-OTM (NCT07480538)
- Testing
- Clear Aligner Therapy, Fixed Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Pain Management, Root Resorption
Photobiomodulation Effect on Vietnamese Orthodontic Patients
Since most orthodontic cases endure for 2 to 3 years or longer, patients are at a high risk of inflammatory root resorption and prolonged orthodontic pain, which is a common and unwanted side effect of their treatment.
- Conditions
- Pain Management, Root Resorption, Orthodontic, Tooth Movement
- Trial name
- NCT07276984
- Testing
- LED device
- Where
- Vietnam
- Volunteers
- 16 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Maxillary Canine Retraction, Local Calcitriol Delivery
Clinical Evaluation of Local Calcitriol Delivery on Maxillary Canine Retraction
This study will evaluate the effect of locally applied Calcitriol on dental and skeletal changes during upper canine retraction.
- Conditions
- Maxillary Canine Retraction, Local Calcitriol Delivery, Orthodontic Tooth Movement
- Trial name
- CALCR25 (NCT07200349)
- Testing
- Calcitriol Delivery
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Maxillary Transverse Deficiency Class I Malocclusion Vitamin D Deficiency Orthodontic Tooth Movement Adolescent Health
Effect of Serum Vitamin D on MARPE Treatment Response
A total of 30 patients are planned to be included in the study during the first half of 2025, who will apply to the clinic. In our clinical routine, approximately 30% of RME patients are treated using the MARPE method.
- Trial name
- NCT06943443
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion (MARPE) Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Orthodontic Tooth Movement, Intrusion of Tooth
Evaluation of Root Resorption Following Different Mandibular Incisors Intrusive Mechanics
Evaluation of root resorption following different mandibular incisors intrusive mechanics : A randomized clinical trial
- Conditions
- Orthodontic Tooth Movement, Intrusion of Tooth, Resorption, Root
- Trial name
- NCT05414019
- Testing
- Mini-screw, Utility arch, Nitinol reverse curve wire
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Tooth Movement, Canine Retraction
Single Versus Repeated Piezocision-assisted Orthodontic Tooth Movement
The primary aim of the study is to evaluate the effect of single and repeated piezocisions on the rate of orthodontic tooth movement.
- Trial name
- NCT05782088
- Testing
- Single Piezocision, Repeated Piezocision
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nourhan M.Aly
Orthodontic Tooth Movement
Impact of Gingival Crevicular Fluid microRNAs on Orthodontic Tooth Movement
A split-mouth study is conducted in order to evaluate the impact of orthodontic movement on the expression of gingival crevicular fluid miRNAs related to inflammation and osteoclastogenesis during canine distalization following…
- Trial name
- NCT06023433
- Testing
- Elastomeric powerchain
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Catania
Low Level Laser Therapy, Canine Retraction
Three-dimensional Assessment of the Bone Changes Accompanying Laser-assisted Orthodontic Tooth Movement
Aim of the present study is to evaluate the effect of low-level laser therapy on bone quality and quantity with orthodontic tooth movement.
- Conditions
- Low Level Laser Therapy, Canine Retraction, Orthodontic Tooth Movement
- Trial name
- NCT05811728
- Testing
- Low level laser therapy, without beam emission
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Orthodontic Tooth Movement, Tooth Alignment
Effect of 3 Week vs 6 Week Orthodontic Appointment Intervals on Teeth Alignment
Effect of 3 week vs 6 week orthodontic appointment intervals on teeth alignment in patients with moderate to severe dental crowding: a randomized clinical trial.
- Trial name
- NCT06032702
- Testing
- tooth alignment
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Effect of Low Level Laser Versus Low Intensity Pulsed Ultra Sound on Rate of Different Orthodontic Tooth Movement by Millimeter
Influence of Low-level Laser Therapy Versus Low-intensity Pulsed Ultrasound on Different Orthodontic Tooth Movements
The aim of this prospective clinical project will be to compare the effect of low-level laser therapy versus low intensity pulsed ultrasound on the rate of different orthodontic tooth movements
- Trial name
- NCT06026930
- Testing
- low-level laser therapy
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Tooth Movement
The Effect of Number of Micro-osteo-perforations on the Rate of Tooth Movement.
The objective of this split mouth trial is to compare mean canine retraction with one Micro-osteo-perforation (MOP) against three MOPs among Class II division I orthodontic patients after one month of intervention.
- Trial name
- MOPs (NCT05995509)
- Testing
- Micro-osteo-perforations
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Orthodontic Tooth Movement
Evaluation of Clinical Approaches to Accelerate Orthodontic Tooth Movement
This study will compare the techniques of piezocision and alveolar corticotomies in accelerating orthodontic retraction movement of canines.
- Trial name
- NCT03089996
- Testing
- Piezocision, Corticotomy, Control Side
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Orthodontic Tooth Movement
Evaluation of Micro-osteoperforations to Accelerate Orthodontic Tooth Movement
This clinical trial evaluated the efficacy of micro osteoperforations in accelerating the retraction of maxillary incisors.
- Trial name
- MOP (NCT05281588)
- Testing
- Micro-osteoperforations
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Orthodontic Tooth Movement
Efficacy of Twin Arch Brackets in the Control of Orthodontic Tooth Movement
To evaluate the efficacy of twin arch brackets compared to conventional brackets in the control of orthodontic tooth movement.
- Trial name
- TAB (NCT05071599)
- Testing
- Twin Arch Brackets
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University