Clinical trials: Oxygenation
Premature; Infant, Light-for-dates, Feeding Patterns
Comparison of Regional Splanchnic Tissue Oxygenation Measured by NIRS in Preterm Babies Fed Bolus Versus Continuous Feeding
Early initiation of enteral feeding, achievement of full enteral feeding and cessation of parenteral nutrition are extremely important in the very premature infant.
- Trial name
- NCT02072109
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Meir Medical Center
Acute Hypoxemic Respiratory Failure
Airway Closure During Extracorporeal Membrane Oxygenation: The AiCLOSE Study
About 65,000 Canadians develop acute respiratory failure requiring breathing machines (ventilators) to give oxygen to their lungs. Unfortunately, up to 50% of these individuals will not survive their illness.
- Trial name
- AiCLOSE (NCT05196074)
- Testing
- Acute hypoxemic respiratory failure patients on VV-ECMO
- Where
- Canada
- Volunteers
- 299 people
- Sponsor
- Lorenzo delSorbo
Vital Signs
The Effect of Postnatal Lying Position on Cerebral Oxygenation in Newborns
In the international delivery room guidelines, it is not specified which position is optimal for the baby stabilization. Here, the investigators want to evaluate the effects of the positions on postnatal adaptation and cerebral…
- Trial name
- NCT05868980
- Testing
- vital signs by postpartum position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Critical Care, Hypoxia
Conservative Versus Liberal Oxygenation Targets in Critically Ill Children
A feasibility study to determine if it is possible to perform a safe, adequately powered, and affordable multi-centre study in critically ill children comparing current practice of liberal targets for systemic oxygen levels with…
- Conditions
- Critical Care, Hypoxia, Pediatric ALL
- Trial name
- Oxy-PICU (NCT03040570)
- Testing
- Conservative oxygenation target, Liberal oxygenation target
- Where
- 3 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Cancer
Hyperbaric Oxygenation Treatment and Quality of Life
Osteoradionecrosis, dermal soft tissue necrosis, radiation cystitis, proctitis and sexual dysfunctions are well-known late-effects after radiation for cancer in the pelvic area, negatively affecting the survivors' quality of life…
- Trial name
- NCT03570229
- Testing
- Hyperbaric oxygen treatment
- Where
- Norway
- Volunteers
- 137 people
- Sponsor
- University of Bergen
Feeding Intolerance, Necrotising Enterocolitis Neonatal
The Effect of Umbilical Vein Catheterization on Splanchnic Oxygenation in Preterm Infants
Objectives: This study aimed to assess the impact of umbilical vein catheter (UVC) placement on splanchnic oxygenation in preterm infants.
- Trial name
- NCT06768203
- Testing
- umbilical vein catheterization, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Eskisehir Osmangazi University
Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation
Cross-sectional Survey of Zhejiang ECMO Application
Extracorporeal lung oxygenation (ECMO) was first used in neonates in the 1970s and is now widely used to treat adult patients with intractable shock and respiratory failure who have failed various types of conventional life…
- Conditions
- Extracorporeal Membrane Oxygenation, Cardiopulmonary Resuscitation, Epidemiology
- Trial name
- NCT04979325
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neonatal Respiratory Distress, Oxygenation
Neonatal Oximeter Bias Study
The study aims to determine if there is a systematic difference (bias) between pulse oximeters used in control systems for automated oxygen delivery (A-FiO2) and those used in monitoring systems.
- Trial name
- NOB (NCT06817850)
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Czech Technical University in Prague
Anemia of Prematurity, Necrotizing Enterocolitis
Transfusion-related Inflammatory Cytokine and Neutrophil Extracellular Trap Quantification in Neonates
Despite many advances in neonatal care, necrotizing enterocolitis (NEC) remains a leading cause of morbidity and mortality among premature infants.
- Trial name
- NCT01735552
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia
Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure
This prospective observational study will evaluate the safety and performance of the MiniLung petite kit in neonatal and pediatric patients with acute respiratory and cardiac failure.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Neonatal Aspiration Pneumonia, Acute Respiratory Failure, Acute Lung Injury
- Trial name
- PETIT (NCT06750536)
- Testing
- MiniLung petite kit combined with the Xenios console
- Where
- 2 sites in Germany
- Volunteers
- 20 people
- Sponsor
- Xenios AG
Platelet Function, Thrombocytopenia
Platelet Function During ECMO (Extra Corporeal Membrane Oxygenation)
Platelet transfusions are routinely administered during neonatal ECMO, with an average of 1.3 platelet transfusions per day being administered while a patient is undergoing ECMO treatment.
- Trial name
- NCT00748878
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Cardiac Arrest
Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be…
- Trial name
- NCT01806844
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Hasselt University
Prematurity of Fetus
The Effect of Mydriatic Eye Drops on Cerebral and Mesenteric Oxygenation in Preterm Infants
Near infrared spectroscopy offers the possibility of noninvasive and continuous bedside investigation of cerebral and mesenteric oxygenation in newborn infants.
- Trial name
- NCT01305720
- Testing
- near infrared spectroscopy: invos 5100
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Scoliosis Patients
Changes in Cerebral Oxygenation Related to Intraoperative Position Changes
This is a prospective, observational study. This study will assess the effect of temporary changes in body position (supine, head of bed elevated 30 degrees, head of bed elevated 60 degrees) in anesthetized patients.
- Trial name
- NCT06910228
- Testing
- Near infrared spectroscopy (NIRS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Joseph D. Tobias
Intermittent Hypoxemia, Apnea of Prematurity
Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm Infants
In this randomized crossover trial, preterm infants with intermittent hypoxemia and need for supplemental oxygen will be randomized to either Sequence of two different oxygen target ranges (low: 85-89%; high: 91-95%) for a total…
- Trial name
- NCT02743988
- Testing
- Oxygen
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Ulm
Brain Injuries
Invasive and Non-Invasive Assessment of Cerebral Oxygenation in Patients With Severe Traumatic Brain Injury (TBI)
The purpose of this study is to investigate the relationship among regional transcranial oxygen saturation (rSO2), brain tissue oxygen pressure (PbtO2) and cerebral perfusion pressure (CPP) in patients with severe traumatic brain…
- Trial name
- NCT00703495
- Testing
- transcranial oxygen saturation measurement (INVOS Somanetics 5100C)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Autism
Effects of Hyperbaric Oxygenation Therapy on Adaptive, Aberrant and Stereotyped Behaviors in Children With Autism
The purpose of this investigation is to evaluate the cognitive and behavioral effects of Hyperbaric Oxygenation Therapy in children who present with a diagnosis of autism and other developmental disabilities.
- Trial name
- NCT00404846
- Testing
- Hyperbaric Oxygenation Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Center for Autism and Related Disorders
Deep Sedation, Dental Treatment
High-flow Nasal Oxygenation During Deep Sedation in Pediatric Dental Patients
It is important to choose an appropriate oxygenation technique during intravenous deep sedation in pediatric dental treatment. The study is to evaluate the efficacy and safety of high-flow nasal oxygenation in intravenous deep…
- Conditions
- Deep Sedation, Dental Treatment, Pediatric Patients
- Trial name
- NCT05762692
- Testing
- High-flow nasal oxygenation device
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University
Tracheal Stenosis, Airway Disease
Endotracheal Dilator to Improve Oxygenation
The purpose of the study is to prospectively assess the use of a modified tracheal balloon dilator in children (<13 years old) with subglottic or tracheal stenosis.
- Conditions
- Tracheal Stenosis, Airway Disease, Pediatric Respiratory Diseases
- Trial name
- EDITION2 (NCT03411928)
- Testing
- Tracheolator
- Where
- South Africa
- Volunteers
- 12 people
- Sponsor
- University of Cape Town
Airway Disorder
Optimizing High Flow Nasal Cannula Oxygenation in Pediatric Airway Procedures
The purpose of this study is to investigate which flow rate (higher versus lower) is most effective at increasing apneic time and preventing greater than 5% drop in desaturation, as well as assessing transcutaneous carbon dioxide…
- Trial name
- NCT06947902
- Testing
- High flow, Low Flow
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston