Clinical trials: PRP
Hepatitis B, Polio
Comparison of a DTaP-IPV-HB-PRP~T Combined Vaccine to Infanrix™-Hexa, When Administered With Prevnar® in Thai Infants
The purpose of the study is to provide immunogenicity and safety data of the investigational hexavalent vaccine when it is given concomitantly (the same day at separate injection sites) with Prevnar, according to the 2-4-6 month…
- Conditions
- Hepatitis B, Polio, Diphtheria, Pertussis
- Trial name
- NCT00401531
- Testing
- DTaP-IPV-HB-PRP~T and Pneumococcal polysaccharide vaccines, DTaP-HB-IPV and Pneumococcal polysaccharide vaccines
- Where
- 2 sites in Thailand
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Senile Vaginitis
Effect of PRP Injection in Releiving of Symptoms of Senile Vaginitis
30 postmenopausal females with senile vaginitis will be enrolled with score of <15 on the Gloria Bachman Vaginal Health Index (VHI) intramucosal injections of PRP will be adminstered and perform clinical evaluations at 0, 1, 3…
- Trial name
- NCT03898401
- Testing
- Platelet rich plasma
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Osteoarthritis Thumb
A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.
This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.
- Trial name
- NCT06193499
- Testing
- Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Diphtheria, Tetanus
Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China
The study will assess the safety of Pentaxim® vaccine as a three-dose primary vaccination at 2, 3, and 4 months of age in order to meet the regulatory requirements for the license renewal as for any other product registered in…
- Conditions
- Diphtheria, Tetanus, Pertussis, Polio
- Trial name
- NCT01491087
- Testing
- DTacP IPV//PRP~T combined vaccine: PENTAXIM®
- Where
- 3 sites in China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Creutzfeldt Jakob Disease
Evaluation of Diagnostic Criteria for Creutzfeldt Jakob Disease
Clinicians know little about Creutzfeldt Jakob disease, and they are not proficient in the diagnostic criteria of Creutzfeldt Jakob disease, so it is easy to misdiagnose or delay the diagnosis.
- Trial name
- NCT04944732
- Testing
- laboratory examination, auxiliary examination, pathological results
- Volunteers
- 30 people
- Sponsor
- Peking University Third Hospital
Chronic Patellar Tendinopathy
Chronic Patellar Tendinopathy (PT)is Prevalent in Participants of Several Sports.A Three-arm, Single-blind Randomized Controlled Trial Will be Conducted. We Want to Compare the Clinical Effectiveness of ESWT Alone, ESWT Combined With Hyaluronic Acid, and ESWT Combined With PRP in Athletes With PT
Chronic patellar tendinopathy is highly prevalent among youth, amateur, and elite athletes, with rates reaching 30-40% in high-performance populations.
- Trial name
- NCT07819968
- Testing
- Extracorporeal Shock Wave Therapy, Hyaluronic Acid (HA), Platelet-Rich Plasma
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Chang Gung Memorial Hospital
Sensorineural Hearing Loss, Tinnitus
Intra-Tympanic Steroid With PRP Combination in Sensorineural Hearing Loss and Tinnitus.
Steroids are used widely for the treatment of Sensorineural hearing loss worldwide. The difficulty lies with efficient delivery of the drug into the cochlea, which is already a sealed chamber with limited blood supply that too…
- Trial name
- NCT06025097
- Testing
- Combination Solution
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Combined Military Hospital Rawalpindi
Necrotic Pulp
Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates
Injectable platelet-rich fibrin (I-PRF) is a flowable blood concentrate that is entirely natural and allows ease of access and flow within the root canal. It was first developed in 2014 by modifying the centrifugation parameters.
- Trial name
- NCT03698188
- Testing
- Injectable platelet-rich fibrin, Platelet-rich plasma
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Haemophilus Influenzae Type B Infection
Immunogenicity of H. Influenzae Type b PRP-OMP Vaccines in American Indian and Alaska Native Children (the HibVax Study)
The main goal of this study is to compare the Haemophilus influenzae type b antibody response in American Indian / Alaska Native (AI/AN) infants to two licensed vaccines: Vaxelis and PedvaxHIB.
- Trial name
- NCT04978818
- Testing
- Vaxelis, PedvaxHIB
- Where
- 5 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Irreversible Pulpitis With Apical Periodontitis
PRP Regenerative Endodontics vs. Root Canal Treatment for Post-Op Pain and Healing in Mature Teeth
This randomized clinical trial aims to compare the effectiveness of regenerative endodontic treatment using platelet-rich plasma (PRP) with conventional root canal treatment (RCT) in mature single-rooted teeth diagnosed with…
- Trial name
- NCT07124962
- Testing
- Root Canal Therapy, Platelet-Rich Plasma (PRP) Revascularization
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- HITEC-Institute of Medical Sciences
Pilonidal Sinus
The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease
The use of local liquid phenol for pilonidal sinus disease was first introduced by Maurica and Greenwood in 1964. Phenol, also known as carbolic acid, has been proven to be an effective sclerosing agent for treating pilonidal…
- Trial name
- NCT06324656
- Testing
- crystallized phenol + platelet rich plasma application, crystallized phenol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Necmi Kadıoğlu Hospital
Periorbital Hyperpigmentation
Efficacy of Platelet-rich Plasma (PRP) in the Treatment of Dark Circles Under the Eyes
10 ml of blood from each patient will be drawn. This blood specimen will be centrifuged in a specific way to get 1 ml of platelet rich plasma (PRP). PRP will be injected into the the skin under the eyes.
- Trial name
- NCT03114514
- Testing
- PRP
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Haemophilus Influenzae Type b
Immunogenicity, Safety & Reactogenicity of GSK Vaccine Tritanrix™-HepB/Hib2.5 Compared to GSK Vaccine Tritanrix™-HepB/Hiberix™
In order to reduce the amount of thiomersal in its vaccines, GSK Biologicals has developed a DTPw-HBV vaccine with low thiomersal content (Tritanrix™- HepB low thio).
- Trial name
- NCT01061541
- Testing
- Tritanrix™-HepB low thio /, Hib 2.5, Tritanrix™-HepB
- Where
- Philippines
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sciatica
Pain Relief by Platelet-rich Plasma (PRP) Treatment
Past PRP therapy is not sufficient for some part of patients.In this clinical research, The integrated application of PRP with extracellurar matrix and some type of stem cell technique.
- Trial name
- NCT01749839
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saint Bernard Mission University
Hepatitis B
Anti-Hep B Antibodies at Age 12 to 18 Months After Hep B Vaccine at Birth and DTaP-IPV-Hep B-PRP-T Hexavalent Vaccine Concomitantly With Prevnar® at 2, 4 and 6 Months of Age
Primary Objective: To describe the persistence of Hep B antibodies (Ab) at 12 to 18 months of age following a three-dose infant primary series vaccination of either Hexaxim®/Hexyon®/Hexacima® or Infanrix® hexa at 2, 4 and 6…
- Trial name
- NCT02610348
- Testing
- DTaP-IPV-HB-PRP~T and Pneumococcal polysaccharide vaccines, DTaP-HB-IPV and Pneumococcal polysaccharide vaccines
- Where
- 2 sites in Thailand
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Skin Burn
Evaluation of Platelet Rich Plasma in Skin Graft Take for Patients With Post Burn Raw Areas
1. To evaluate the effect of the platelet rich plasma on the take of split thickness skin graft and its early and late results in resurfacing of post burn raw areas. 2.
- Trial name
- NCT05996614
- Testing
- PRP in skin grafts, conventional methods in skin grafts
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acne Atrophica, PRP
Poly-L-Lactic Acid Threads Versus Platelet-Rich Plasma for Post-Traumatic Atrophic Scars
This study compares the efficacy and safety of poly-L-lactic acid (PLLA) threads versus platelet-rich plasma (PRP), both combined with subcision, in the treatment of post-traumatic atrophic scars.
- Trial name
- PLLA-PRP PTAS (NCT07775092)
- Testing
- subcision and PLLA threads' insertion, PRP and subcision (PRP-S)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Tanta University
Autism Spectrum Disorder
Combined Photo-Biomodulation At Acupuncture Points, Autologous PRP, and Umbilical Cord-Derived Exosome Therapy in Autism Spectrum Disorder
This randomized controlled trial aims to evaluate the efficacy of a combination of photo-biomodulation at acupuncture points, autologous platelet-rich plasma (PRP), and umbilical cord-derived exosome therapy in children with…
- Trial name
- Biomodulation (NCT06600529)
- Testing
- Photo-Biomodulation, Autologous PRP, Exosome Therapy
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Iffat Anwar Medical Complex
COPD, Interstitial Lung Disease
Autologous Stem Cell Treatment for Chronic Lung Disease Study
The purpose of the Lung Institute is to collect and isolate a patient's own cells and platelet rich plasma (PRP) and deliver the product back to the patient the same day.
- Trial name
- NCT03044431
- Testing
- Cell therapy
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Lung Institute
Alopecia Areata
Transepidermal Delivery of Triamcinolone Acetonide or Platelet Rich Plasma Using Either Fractional Carbon Dioxide Laser or Microneedling in Treatment of Alopecia Areata
The aim of this study is to evaluate the use of fractional carbon dioxide laser versus microneedling in the transepidermal delivery of triamcinolone acetonide and platelet rich plasma in treatment of alopecia areata.
- Trial name
- NCT04147845
- Testing
- Fractional Carbon Dioxide Laser, Microneedling using dermapen, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University