Clinical trials: Paediatric Trauma
Seizure
OPALS Pediatric Study
The OPALS Pediatric Study will examine the incremental impact of introducing a prehospital full advanced life support in pediatric patients.
- Trial name
- NCT00298532
- Testing
- Advanced Life Support
- Where
- 10 sites in Canada
- Volunteers
- 9,000 people
- Sponsor
- Ottawa Hospital Research Institute
Head Trauma
Is a Two-Film Skull X-ray Series as Sensitive as a Four-Film Series in the Diagnosis of Skull Fractures in Paediatric Patients
Minor head injuries are a common presenting complaint in the pediatric emergency department. Skull x-rays are a useful tool in the evaluation of paediatric patients with a history of minor head trauma.
- Trial name
- 4vs2 (NCT01448473)
- Testing
- 4-views series, 2-views serie
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- St. Justine's Hospital
Renal Failure, CVVHD
Analysis of Paediatric Treatments With multiFiltratePRO
This clinical study evaluates the performance of the MultifiltratePro in pediatric mode for Continuous Venovenous Hemodiafiltration (CVVHD) in children.
- Trial name
- ECHOped (NCT06603324)
- Testing
- CVVHD treatment in paediatric mode with multiFiltratePRO
- Where
- 2 sites in Czechia, Germany
- Volunteers
- 43 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Brain Concussion, Mild Traumatic Brain Injury
A Study on the Effect of Mindfulness-based Yoga on Youth With Persistent Concussion Symptoms
Mild traumatic brain injury (mTBI), also known as concussion, is of great concern in the youth population, with incidences of injury steadily increasing within the past few years.
- Trial name
- NCT03217695
- Testing
- Mindfulness-based Yoga Arm
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Pain, Procedural
Oral Morphine Versus Ketamine in Pain Management
The study will mainly focus on procedural pain management using oral morphine versus rectal ketamine during paediatric burn and wound dressing at Mbarara Regional Referral Hospital.
- Trial name
- NCT05163366
- Testing
- GROUP A, GROUP B
- Where
- 2 sites in Uganda
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Traumatic Brain Injury
Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics
To improve patient selection for head CT, a safe and high sensitivity screening neuroimaging modality is needed. Currently many clinicians must make treatment decisions based solely on the patients clinical exam, which has low…
- Trial name
- CUPID-Peds (NCT06697808)
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Wake Forest University Health Sciences
Burns Degree Second, Pediatric
Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings
Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO).
- Trial name
- CHITAG (NCT06987981)
- Testing
- Chitosan-based dressing, Silver-based dressing
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Miloš Potkonjak
Fractures, Bone
Retrospective Study on Clinical Performance and Safety Profile of MJ-Flex Elastic Nail
This study aims to retrospectively collect data from routine clinical practice in order to evaluate the safety profile of the MJ-FLEX elastic nail used in pediatric patients according to the manufacturer Instructions For Use…
- Trial name
- MJ-Flex (NCT06412913)
- Testing
- MJ-Flex The New Metaizeau Nail
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Orthofix s.r.l.
Paediatric Thyrotoxicosis
Antithyroid Drug Treatment of Thyrotoxicosis in Young People
The investigators aim to establish whether biochemical control during anti-thyroid drug therapy in young people with thyrotoxicosis varies depending upon whether a 'block and replace' or 'dose titration' regimen is used.
- Trial name
- NCT01436994
- Testing
- Block and Replace, Dose Titration, carbimazole
- Where
- 18 sites in United Kingdom
- Volunteers
- 81 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Congenital Heart Disease
Paediatric Brain Injury Following Cardiac Interventions
Children born with congenital heart problems face numerous physical, developmental, and social challenges. Complications in pregnancy have potential to impair brain development, leading a smaller brain volume and less mature…
- Trial name
- BICI2Kids (NCT04992793)
- Testing
- Congenital heart surgery
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University of Leicester
Acquired Brain Injury, Cerebral Palsy
Movement Improvement After Paediatric Armeo®Spring Rehabilitation
Children with acquired and congenital brain lesions (namely, cerebral palsy, CP, and acquired brain injury, ABI) may exhibit upper limb impairment, with consequent limitations in their daily living activities.
- Trial name
- NCT03552614
- Testing
- Upper limb robot-assisted rehabilitation, physiotherapy
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- IRCCS Eugenio Medea
Pediatric Trauma
Preventable Paediatric Trauma - Retrospective Analysis
Purpose: a retrospective study of all Paediatric patients who presented to Ziv Medical Centre with injuries of all systems, major and minor, in order to determine the exact circumstances of the injury, whether this might have…
- Trial name
- NCT01825343
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Ziv Hospital
Traumatic Brain Injury (TBI)
Prognostic Model for Predicting Outcome After Moderate to Severe Paediatric Traumatic Brain Injury
Due to ethical and logistical challenges related to paediatric research, there is limited age-appropriate evidence for managing paediatric traumatic brain injury (pTBI).
- Trial name
- PROMPT (NCT07538440)
- Where
- United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Laceration
A Randomized Post-market Study to Evaluate Zip Device Compared to Sutures for Laceration Repair in Pediatrics and Adults
The Zip-009 clinical investigation will enroll 26 paediatric and adult subjects requiring laceration repair and fulfilling the eligibility criteria for the clinical investigation.
- Trial name
- NCT03199456
- Testing
- Zip surgical skin closure device, Standard of Care sutures
- Where
- 2 sites in Sweden
- Volunteers
- 26 people
- Sponsor
- ZipLine Medical Inc.
AKI, ICU
What Are the Predictors of Acute Kidney Injury in Children Admitted to Pediatrics Intensive Care Unit at Assiut University Children Hospital?
Identify the Predictors of Acute Kidney Injury in critically ill children admitted to PICU during one year
- Trial name
- NCT07517939
- Testing
- Clinical and laboratory assessment
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pain, Burns
VR for Pediatric Burn Dressing Changes
This study evaluated a smart phone virtual reality (VR) to manage pediatric burn dressing pain. A randomized controlled trial was conducted among 90 patients (6-17 years).
- Trial name
- NCT04544631
- Testing
- Virtual reality game as adjunctive pain management tool
- Volunteers
- 90 people
- Sponsor
- Nationwide Children's Hospital
Upper Limb Injury, Virtual Reality
Using Virtual Reality for Rehabilitation of Upper Limbs at Home Trial
The IVR games have been enhanced to include more levels. The new aspects to be tested in this study are new IVR exercises that would be made upper limb rehab designed for children for home use, as repeated sessions with…
- Conditions
- Upper Limb Injury, Virtual Reality, Rehabilitation, Paediatric
- Trial name
- NCT05272436
- Testing
- Virtual Reality Upper Limb Motor Impairment Rehabilitation
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Sheffield Hallam University
Cerebral Palsy (CP), Brain Injuries
Acceptability of Paediatric Wrist Orthoses Through Co-design
The goal of this pilot interventional study (pre-post design) is to learn if a co-designed wrist-hand orthosis can improve acceptability compared to a conventional orthosis in children aged 6 to 14 years with neuromotor disorders…
- Conditions
- Cerebral Palsy (CP), Brain Injuries, Neuromotor Dysfunction
- Trial name
- NCT07861958
- Testing
- Orthosis acceptability
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- IRCCS Eugenio Medea
Epidermolysis Bullosa
The Efficacy of Trimethoprim in Wound Healing of Patients With Epidermolysis Bullosa
The purpose of this study is to assess the efficacy of trimethoprim in promoting wound healing and decreasing blister formation in patients with Epidermolysis Bullosa.
- Trial name
- NCT00380640
- Testing
- Trimethoprim
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children
Developmental Dysplasia of Hip, DDH
8 vs 12 Weeks: A Pavlik Harness Trial
Developmental dysplasia of the hip is the most common bone and joint condition in babies. It is usually treated with a harness that holds the hips in a safe position so they can develop normally.
- Conditions
- Developmental Dysplasia of Hip, DDH, Developmental Dysplasia of the Hip, Developmental Dysplasia of the Hip (DDH)
- Trial name
- NCT07847619
- Testing
- Pavlik Harness
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- The Hospital for Sick Children