Clinical trials: Pain Response
Patellofemoral Pain Syndrome
Pain and Movement Responses to Resistance Training to Muscular Failure in Patients With Patellofemoral Pain
This study aims to investigate the effect of training to muscular failure in patients with patellofemoral pain (PFP). In a cross-sectional observational design, participants with PFP will be be performing a knee exercise to…
- Trial name
- NCT07812519
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ted Gunhamn
Fear is a Common Psychological Response Undergoing Medical Procedures,Act From Uncertainty, Anticipation of Pain, Loss of Control, Previous Negative Experiences
(Effect of Toy Nebulizer Versus Distraction Cards on Children's Fear and Parental Satisfaction During Nebulization Therapy: A Comparative Study
Goal To compare the effectiveness of a toy nebulizer versus distraction cards in reducing fear among children during nebulization therapy while improving parental satisfaction.
- Trial name
- NCT07417839
- Testing
- distraction card, Nebuliser toy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
Migraine, Common Migraine
A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine
The purpose of this study is to evaluate the safety and efficacy of three doses of topiramate (50 milligrams[mg], 100mg, and 200mg per day) compared with placebo in the prevention of migraine.
- Conditions
- Migraine, Common Migraine, Classic Migraine, Headache
- Trial name
- NCT00231595
- Testing
- topiramate
- Volunteers
- 768 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Pain and Emotional Responses in Children During Venous Blood Sampling
Pinwheel and Bubble Blowing for Pain and Emotional Responses in Children
Venous blood sampling is one of the most frequently performed invasive procedures in children during diagnostic and treatment processes and may lead to pain, fear, and negative emotional responses.
- Trial name
- NCT07443735
- Testing
- Bubble Blowing Group, Pinwheel Group
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Trakya University
Postoperative Pain, Oxidative Stress Response
Analgesic and Antioxidant Effects of Melatonin in Pediatric Surgery
Background. Long-term consequences of postoperative pain are detrimental in children. We tested the hypothesis that melatonin reduces postoperative pain and oxidative stress involving sirtuin pathway in children undergoing…
- Trial name
- NCT06724432
- Testing
- oral melatonin
- Where
- 2 sites in Italy
- Volunteers
- 44 people
- Sponsor
- University of Parma
Posterior Fossa Tumors
The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in Posterior Fossa Surgery
This study evaluate the effects of scalp block versus local infiltration on haemodynamic response to head pin replacement and skin incision and postoperative analgesia in posterior fossa surgery
- Trial name
- NCT02852382
- Testing
- Bupivacaine, morphine patient controlled analgesia
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Premature Infant, Pain
The Effect of Breast Milk Odor on Pain Response and Salivary Cortisol Level in Preterm Infants
The aims of this randomized controlled trial are investigate the effects of breast milk odor on pain response and saliva cortisol level duration heel stick blood sampling in preterm infants.
- Conditions
- Premature Infant, Pain, Breast Milk Odor
- Trial name
- NCT05557435
- Testing
- breast milk odor
- Volunteers
- 64 people
- Sponsor
- Taipei Medical University
Pain Management
Impact of Breast Milk on Cortical Pain Response in Newborns
Background:Newborns are exposed to painful procedures for many different reasons in the first days of their life. If pain is not relieved effectively in these newborns, neurodevelopmental and behavioral problems may occur in the…
- Trial name
- NCT05961904
- Testing
- Breastmilk
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Procedural Pain, Preterm Infants
Parental Involvement in Pain Reducing Measures
This pilot study was conceptualised to determine the feasibility of involving parents via facilitated tucking or observing during painful procedures and to measure change in parental stress and infant pain.
- Conditions
- Procedural Pain, Preterm Infants, Parents
- Trial name
- NCT05656677
- Testing
- Passive parental involvement, Active parental involvement
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Children Who Need Circumcision
Assessment of Hemodynamic Response in Surgery of Circumcision in Children
The surgery stress relives systemic inflammatory response by hormones and adrenergic receptors. When the pro-inflammatory mediator is higher than anti-inflammatory response, the physiologic status is impaired and the patient is…
- Trial name
- NCT00943475
- Testing
- circumcision
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Pain
The Holding Study: Feeding Analgesia in Preterm Infants
The purpose of this study is to compare the effects of mothers' skin-to-skin holding during feeding via a soother trainer with the effects of pacifier sucking on preterm infant biobehavioural responses during and immediately…
- Trial name
- NCT00414258
- Testing
- breastfeeding
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain, Stress, Physiological
The Effect of a Musical Intervention on Stress Response to Venepuncture
Randomised Crossover Trial in Preterm Infants less than 32 weeks to assess Music therapy and sucrose versus sucrose on stress
- Trial name
- NCT03028844
- Testing
- Music therapy
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- University College Cork
Pain, Stress
Study of Spirit Pass in Newborn and Patient
Stress is a multiple variable and an inevitable aspect of life. Any change that affects the life of a person is a stressful agent, being possible to widely vary its nature and may be formed by several components, since…
- Trial name
- SSPNP (NCT02489136)
- Testing
- laying of hands (Spiritist "passe")
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Triangulo Mineiro
Pain, Chronic Widespread Pain
Enhancing Analgesia in Chronic Pain Through Exercise
Background: Current pain management strategies for pediatric patients are not integrating the analgesic potential of movement-based therapies.
- Conditions
- Pain, Chronic Widespread Pain, Fibromyalgia
- Trial name
- NCT04862871
- Testing
- Physical Activity - Pediatric Pain Rehabilitation Center
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Surgery
Animal-assisted Therapy in Pediatric Surgery: Post-operative Benefits
The relationship between human beings and animals, especially dogs, has existed for thousands of years. Historically, animals have held an important role in this relationship as they provide company, stimulus and motivation.
- Trial name
- NCT02284100
- Testing
- animal assisted therapy
- Volunteers
- 40 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Pain, Retinopathy of Prematurity
Proparacaine and Mydriatic Eye Drops
In this study, we will be evaluating whether premedication with an anesthetic eye drops leads to a decreased sensation of pain when given dilating eye drops prior to eye examinations to evaluate for retinopathy of prematurity in…
- Trial name
- NCT01266824
- Testing
- Proparacaine Hydrochloride Ophthalmic Solution
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Children's Hospital of Philadelphia
Anesthesia, Pain
Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia
The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to…
- Trial name
- NCT02703090
- Testing
- Remifentanil, Normal saline
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston Children's Hospital
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program?
The purpose of this study is find out if we can use simple tests (biomarkers) to tell us if a specific child would benefit most from CBT or from the low FODMAPs diet.
- Conditions
- Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Functional Bowel Disorder
- Trial name
- NCT03823742
- Testing
- Cognitive Behavioral Therapy, Low FODMAP Diet
- Where
- 2 sites in United States
- Volunteers
- 163 people
- Sponsor
- Baylor College of Medicine
Allergy Testing, Pain, Emotional Symptoms and Physiological Parameters
Pet Therapy Effects on Pain, Emotional and Physiological Responses in Children Undergoing Allergy Testing
In recent decades, the prevalence of allergic diseases, particularly respiratory allergies, has risen significantly. In childhood, house dust mites are the primary indoor allergen in infancy, while the prevalence of pollen…
- Trial name
- NCT06875999
- Testing
- animal assisted therapy
- Volunteers
- 80 people
- Sponsor
- Mehtap METİN KARAASLAN