Clinical trials: Pain Response
Pain Response
Active vs Passive Distraction on Procedural Pain in the Pediatric Emergency Department
The investigators proposed study will investigate the efficacy of tablet computer distraction as an analgesic for the pain associated with various painful procedures in the emergency department.
- Trial name
- NCT01960166
- Testing
- Active Distraction, Passive Distraction
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Children Who Need Circumcision
Assessment of Hemodynamic Response in Surgery of Circumcision in Children
The surgery stress relives systemic inflammatory response by hormones and adrenergic receptors. When the pro-inflammatory mediator is higher than anti-inflammatory response, the physiologic status is impaired and the patient is…
- Trial name
- NCT00943475
- Testing
- circumcision
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Chronic Pancreatitis, Chronic Pain
Pancreatic Quantitative Sensory Testing (P-QST)
Quantitative Sensory Testing (QST) is a novel investigative technique used in other pain conditions to evaluate patterns of chronic pain, and in this study will be used to elucidate pain patterns in patients with Chronic…
- Conditions
- Chronic Pancreatitis, Chronic Pain, Acute Recurrent Pancreatitis
- Trial name
- NCT06996535
- Testing
- Quantitative Sensory Test 1, Quantitative Sensory Test 2, Quantitative Sensory Test 3
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Dental Anxiety
Comparison of Dental Pain Response in Children
Study involves the observation of the child's behavior during a dental treatment procedure. This allows for the evaluation of the child's experience of pain and discomfort through their facial expressions, body movements, and…
- Trial name
- NCT05883566
- Testing
- experimental
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Pain, Withdrawal
Evaluation of the Effect of Venous Diameter Measurement by Ultrasonography on Pain and Withdrawal Response
During general anesthesia, intravenous (IV) medications can disrupt the patient's comfort by causing a pain sensation or a withdrawal response in the heart.
- Trial name
- VDIAMETER (NCT03376308)
- Testing
- Pain Score, Withdrawal movement score, hemodynamic response
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Labor Pain
The Response Patterns to the Electrical Stimulation of Epidural Catheters With Varying Pulse Widths in Term Pregnant Women
Epidural analgesia is commonly used for labor pain relief due to its safety and effectiveness. Despite a very high success rate, the epidural technique remains a somewhat blind technique and failures continue to occur.
- Trial name
- NCT02762149
- Testing
- Nerve stimulator
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Preterm Birth, Pain
Effects of Music Based Intervention (MBI) on Pain Response and Neurodevelopment in Preterm Infants
Pilot prospective randomized, double blinded, controlled study to test effect of music based intervention (MBI) on pain response and neurodevelopment in preterm infants.
- Trial name
- NCT04286269
- Testing
- Music Based Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pain
The Holding Study: Feeding Analgesia in Preterm Infants
The purpose of this study is to compare the effects of mothers' skin-to-skin holding during feeding via a soother trainer with the effects of pacifier sucking on preterm infant biobehavioural responses during and immediately…
- Trial name
- NCT00414258
- Testing
- breastfeeding
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Patellofemoral Pain Syndrome
Pain and Movement Responses to Resistance Training to Muscular Failure in Patients With Patellofemoral Pain
This study aims to investigate the effect of training to muscular failure in patients with patellofemoral pain (PFP). In a cross-sectional observational design, participants with PFP will be be performing a knee exercise to…
- Trial name
- NCT07812519
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ted Gunhamn
Muscle Soreness
Neuromuscular Responses to Recovery Techniques
Cold water immersion (CWI) and percussive massage therapy (PMT) are commonly used re-covery techniques in team sports. In particular, despite its wide use, PMT has been scarcely investigated in the literature, especially…
- Trial name
- NCT06433856
- Testing
- Cold Water Immersion, Percussive Massage Therapy
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Anxiety Wounds and Injuries
Healing Through Play
Wound dressing is a common procedure for children with injuries or wounds. The procedure can cause pain, fear, and anxiety. Children may also experience changes in heart rate and breathing when they feel distressed.
- Trial name
- Healing (NCT07909798)
- Testing
- Usual Care
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
Pain, Acute, Preterm Infant
Olfactive Stimulation Interventions With Mothers' Milk on Preterm Pain Response
Repeated and untreated pain can lead to long-term consequences in preterm infants, such as pain hypersensitivity and impaired motor and intellectual development.
- Conditions
- Pain, Acute, Preterm Infant, Breast Milk
- Trial name
- NCT04062513
- Testing
- Olfactive stimulation intervention with familiarization, Olfactive stimulation intervention, Standard care
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Pain and Emotional Responses in Children During Venous Blood Sampling
Pinwheel and Bubble Blowing for Pain and Emotional Responses in Children
Venous blood sampling is one of the most frequently performed invasive procedures in children during diagnostic and treatment processes and may lead to pain, fear, and negative emotional responses.
- Trial name
- NCT07443735
- Testing
- Bubble Blowing Group, Pinwheel Group
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Trakya University
Fear Pain
Human Behaviors Related to the Expectation of Pain
The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear.
- Trial name
- NCT03739645
- Testing
- Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pain
Does the Order in Which Vaccines Are Administered Affect Pain Response?
The objective of this study is to determine whether there should be a predetermined sequence recommended for administering these two vaccines, with the less painful vaccine being given first.
- Trial name
- NCT00390130
- Testing
- Pentacel (DPTaP+Hib), Prevnar (conjugated pneumococcal vaccine)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Analgesia
Newborn Cortical Response to Pain and Non Pharmacological Analgesia
Minor painful procedures are frequently performed on newborn infants and non-pharmacological analgesia is commonly used. As more than one analgesic method may be applied simultaneously in clinical practice, the relative…
- Trial name
- NCT03389789
- Testing
- Oral glucose solution + maternal holding, Breastfeeding, Oral glucose solution
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS Burlo Garofolo
Pain Management
Impact of Breast Milk on Cortical Pain Response in Newborns
Background:Newborns are exposed to painful procedures for many different reasons in the first days of their life. If pain is not relieved effectively in these newborns, neurodevelopmental and behavioral problems may occur in the…
- Trial name
- NCT05961904
- Testing
- Breastmilk
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Pain, Chronic Widespread Pain
Enhancing Analgesia in Chronic Pain Through Exercise
Background: Current pain management strategies for pediatric patients are not integrating the analgesic potential of movement-based therapies.
- Conditions
- Pain, Chronic Widespread Pain, Fibromyalgia
- Trial name
- NCT04862871
- Testing
- Physical Activity - Pediatric Pain Rehabilitation Center
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pain
Cardiac Autonomic Reactivity and Behavioral Response to Pain in Full-Term Neonates
Background: Heel lancing is a routine procedure for the diagnosis of phenylketonuria in infants. Despite the short- and long-term adverse effects of pain, there are no guidelines for the reduction of such pain.
- Trial name
- NCT00396838
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Infant, Newborn, Infant, Premature
Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates
The assessment and treatment of pain in neonates remains a challenge. In an effort to improve the quality of care while limiting opioid-related adverse effects, this study aims to determine the efficacy of a non-pharmacological…
- Conditions
- Infant, Newborn, Infant, Premature, Pain Perception, Pain Measurement
- Trial name
- NCT04050384
- Testing
- Baby GentleStick
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Lance M Relland, MD, PhD