Clinical trials: Peripheral Blood Flow
Traumatic Brain Injury, Intracranial Hypertension
Investigating CBF and ICP Using DCS
We aim to acquire data using DCS on patients who are undergoing invasive ICP and ABP monitoring on ITU as part of their normal treatment. Data will then be correlated to derive various parameters including CBF and BFI.
- Trial name
- ICP-CBF (NCT06039098)
- Testing
- DCS
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Queen Mary University of London
Osteoarthritis, Knee
Effects of Blood-flow Restricted Exercise Compared to Standard Rehabilitation in Patients With Knee Osteoarthritis
The purpose of this study is to investigate the effect of low-intensity BFR exercise on joint pain, muscle mass, and mechanical muscle function compared to standard rehabilitering in adults with knee-OA.
- Trial name
- NCT05437770
- Testing
- BFR (Blood-Flow Restricted exercise), Standard rehabilitation
- Where
- Denmark
- Volunteers
- 96 people
- Sponsor
- Bispebjerg Hospital
Cervical Spinal Cord Injury
Blood Flow Restriction Resistance Exercise in Lower Cervical Spinal Cord Injury Patients
This study is conducted to investigate the effects of low load Blood Flow Resistance exercise to improve strength and transfer in lower cervical spinal cord injury patientsCervical Spinal Cord injury patients have very less…
- Trial name
- NCT05425238
- Testing
- Blood flow restriction, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University
Premature Birth, Extremely Low Birth Weight
DCS Study in Extremely Premature Newborns
The researchers are attempting to improve the cerebral monitoring of extremely low gestational age (ELGA) infants, such that in the future, real-time monitoring will be possible, to aid clinicians in management of these infants.
- Conditions
- Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
- Trial name
- NCT04367181
- Testing
- Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Maria Angela Franceschini
Endometrial Receptivity
Comparison of Blood Flow in the Arteriae Uterinae in Ovarian Stimulation Cycles
This study will measure the blood flow in the aa. uterinae in women, undergoing firstly ovarian stimulation for In-Vitro Fertilization (IVF) / Intracytoplasmic sperm injection (ICSI), in Hormonal Replacement cycles (HRT) and…
- Trial name
- NCT03887728
- Where
- United Arab Emirates
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Healthy Subjects, Sports Level 1
Effect of Blood Flow Restriction Training to Muscle Strength, Dynamic Stability, and ACL Injury Prevention
The goal of this randomized clinical trial study is to compare low-load blood flow restriction (LL-BFRt), sham LL-BFRt, and high-load eccentric training (HL-Et) in healthy level 1 sportsman.
- Trial name
- NCT05951036
- Testing
- Low-load Blood Flow Restriction training, High-load Eccentric training
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Udayana University
Hypotension (MeSH: D007022)
Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 Years
Blood pressure is routinely monitored during anesthesia in children, but blood pressure alone may not accurately reflect blood flow to vital organs.
- Trial name
- CARFLOW (NCT07847203)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Raynaud's Disease
Safety and Efficacy of Pletal (Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon
Juvenile secondary Raynaud's (ray-knows) Phenomenon is a disorder of the blood vessels in the fingers and sometimes can affect the toes, nose, or ears.
- Trial name
- NCT00048776
- Testing
- Pletal
- Where
- 19 sites in United States
- Volunteers
- 75 people
- Sponsor
- Otsuka America Pharmaceutical
Physical Fitness, Muscle Strength
Effects of Blood Flow Restriction Training on Body Composition and Maximal Strength in Military Personnel
This study aims to compare the effects of low-intensity blood flow restriction training combined with resistance training versus traditional high-intensity resistance training on body composition (skeletal muscle mass, body fat…
- Conditions
- Physical Fitness, Muscle Strength, Body Composition
- Trial name
- NCT07628478
- Testing
- KAATSU Master Pneumatic Cuff, High-Load Resistance Training
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yang Liu
Diabetes Mellitus, Kidney, CPB
Kidney Function in Diabetics During CPB (Cardio Pulmonary Bypass)
Filtration of urine in the kidney requires sufficient oxygen supply. The filtration of urine is greater in patents with diabetes.
- Trial name
- DM-ECC (NCT03405532)
- Testing
- DM-ECC
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Traumatic Brain Injury, Subarachnoid Hemorrhage
Cerebral Blood Flow (CBF) Disturbances Following Traumatic Brain Injury (TBI) and Subarachnoid Hemorrhage (SAH)
It is a "proof of concept" study, aimed to evaluate whether the "optimal CPP", defined by the best PRx, corresponds to the acceptable CBF values in patients affected by CBF disfunction caused by TBI or SAH.
- Trial name
- NCT00807833
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliera San Gerardo di Monza
Raynaud's Disease
Safety and Efficacy of Pletal(Cilostazol) for the Treatment of Juvenile Primary and Secondary Raynaud's Phenomenon
Juvenile primary Raynaud's (ray-knows) Phenomenon is a disorder of the blood vessels in the fingers and sometimes can affect the toes, nose, or ears.
- Trial name
- NCT00048763
- Testing
- Pletal
- Where
- 18 sites in United States
- Volunteers
- 75 people
- Sponsor
- Otsuka America Pharmaceutical
Improving Quality of Life
Uterine Cavity and Blood Flow After Conservative Management of Placenta Previa/Accreta
Bleeding is the most significant cause of maternal death worldwide with more than half of those occurring within the first day of delivery.
- Trial name
- NCT02878187
- Testing
- Doppler
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
ACL Injury
BFR Therapy for Post-Op Rehab of ACL Reconstruction With Quadriceps Tendon Autograft
The overall objective of the proposed research is to conduct a prospective, randomized controlled trial to investigate whether the addition of BFR therapy to standard post-operative rehabilitation regimen significantly improves…
- Trial name
- NCT04519801
- Testing
- Blood Flow Restriction (BFR) therapy, Standard REHAB
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Brooke Army Medical Center
Sickle Cell Disease
Safety and Efficacy of Sodium Nitrite in Sickle Cell Disease
This study will determine if administration of sodium nitrite is safe and can improve small vessel blood flow and tissue oxygenation when given as an additional treatment in patients with acute vaso-occlusive crisis (pain crisis)…
- Trial name
- NCT01033227
- Testing
- sodium nitrite injection, usp
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Children's Hospital Los Angeles
Drop Foot
The Investigators Are Comparing Lidocaine and Papaverine Nerve Blocks to Determine Which Improves Blood Flow Better, Making the "Phoenix Sign" Clearer on Imaging. This Helps Accurately Diagnose Nerve Compression, Improving Patient Care
This pilot study aims to investigate the effects of nerve blocks in patients with diabetic peripheral neuropathy through a double-blinded, randomized trial involving 4 patients.
- Trial name
- NCT06919289
- Testing
- Infiltration of papaverine, Lidocaine infiltration
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- US Neuropathy Centers
Poor Peripheral Perfusion
Perfusion Index Variability in Respiratory Distress Syndrome
Perfusion index may vary according to type of surfactant during the treatment of respiratory distress syndrome.
- Trial name
- NCT01852461
- Testing
- Beractant, Poractant alfa
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Dr. Sami Ulus Children's Hospital
Anterior Cruciate Ligament Injury
Blood Flow Restriction to Improve Muscle Strength After ACL Injury
Quadriceps muscle weakness is a common consequence following anterior cruciate ligament (ACL) injury and reconstruction. Maximizing quadriceps strength following ACL injury is significant as diminished quadriceps strength has…
- Trial name
- NCT03141801
- Testing
- DELFI PTS Personalized Tourniquet System for Blood Flow Restriction Training, Eccentric Exercise with BLAST Leg Press System, Concentric Exercise with BLAST Leg Press System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Michigan
Concussion
Vascular Assessment of Regulation Index Arrays Registry
The objective of this patient registry is to collect and analyze physiological data associated with baseline and brain injury identified in standard clinical practice (Normal Values, Recovery Curves, Correlation between Symptoms…
- Trial name
- VARIA (NCT02435082)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- NeuroChaos Solutions, Inc.
Perfusion Index
The Role of Perfusion Index in Children
The purpose of our study is to test the usability of the perfusion index in evaluating the success of the peripheral nerve block applied under sedation in children.
- Trial name
- NCT04245735
- Testing
- perfusion index
- Volunteers
- 60 people
- Sponsor
- Erzincan University