Clinical trials: Peripheral Blood Flow
Stroke
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance.
- Trial name
- MITO (NCT06930638)
- Testing
- Ischemic Conditioning, Antioxidant Supplement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical College of Wisconsin
Fibromyalgia
Effects of Aerobic Exercise Training With and Without Blood Flow Restriction in Fibromyalgia
In our study, we aimed to evaluate and compare the effects of low-intensity aerobic exercise training with blood flow restriction and without blood flow restriction, on pain, functional status, quality of life and catecholamine…
- Trial name
- NCT04500444
- Testing
- exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Ischemic Heart Disease (IHD), Cardiac Magnetic Resonance Imaging
The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study
This research aims to investigate whether symptoms of chest pain or shortness of breath among the study population are arising due to a heart problem, particularly any reduction of blood flow to the heart muscle from blockages in…
- Conditions
- Ischemic Heart Disease (IHD), Cardiac Magnetic Resonance Imaging, Myocardial Blood Flow
- Trial name
- SPINS2 (NCT06854458)
- Testing
- Quantitative Myocardial Blood Flow Evaluation, Qualitative Myocardial Blood Flow Evaluation, Gadavist
- Where
- 13 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Brigham and Women's Hospital
Myeloma Multiple
The Risk Stratification in Patients With Multiple Myeloma Based on Fluorescence Flow Cytometry Quantitative Determination of the Circulating Plasma Cells in the Peripheral Blood
The main aim of this study is to evaluate the effectiveness of the clinical application of the XN-1000/20 hematology analyzer for risk stratification in patients with multiple myeloma based on the number of detected plasma cells…
- Trial name
- NCT04242121
- Testing
- fluorescence flow cytometry
- Where
- Russia
- Volunteers
- 24 people
- Sponsor
- Ivan S Moiseev
End Stage Renal Disease, Arteriovenous Fistula
Effect of Pre-operative Forearm Exercises on Arterial Venous Fistula Maturation and Blood Flow
This study will investigate the effect of pre-operative exercise on hemodynamics in the fistula artery and vein, Pre and Post Arteriovenous Fistula Formation as well as the suitability of Cannulation of Arteriovenous Fistula at…
- Trial name
- NCT03886116
- Testing
- Exercise
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Singapore General Hospital
Chronic Ankle Instability,CA
Study on the Effect of Exercise Intervention Combined With Physical Therapy on Chronic Ankle Instability Symptoms
Purpose; Through experimental observation of exercise intervention (blood flow restriction training combined with low load ankle muscle strength training and balance training) combined with instrument tool therapy (Instrument…
- Trial name
- CAI (NCT06251414)
- Testing
- Exercise Intervention, Instrument-Assisted Soft Tissue Mobilization, Tuinal
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Yang Liu
Healthy Individuals
Effects of Exercises Combined With Blood Flow Restriction in Healthy Individuals
Purpose of the study is; to investigate the effect of exercises combined with blood flow restriction on strength, proprioception and functional motor performance in healthy individuals.
- Trial name
- NCT03401567
- Testing
- Exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Patellofemoral Pain Syndrome
Blood Flow Restriction Therapy in Patellofemoral Pain Syndrome
The purpose of this study is to determine the efficacy of blood restriction therapy by comparing increase in muscle mass and strength in patients that receive blood restriction therapy to patients who receive a placebo.
- Trial name
- NCT03717532
- Testing
- Personalized Tourniquet System for Blood Flow Restriction
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Chronic Fatigue Syndrome
Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS
Use of Viagra to Alter Symptoms in Patients with Chronic Fatigue Syndrome (CFS)
- Trial name
- NCT00598585
- Testing
- Sildenafil (Viagra)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Sepsis, Shock, Septic
Comparison of Peripheral Perfusion Indicators and Lactate Levels
In patients with septic shock undergoing intensive care unit monitoring, routine assessment of arterial and/or venous blood gas is conducted.
- Conditions
- Sepsis, Shock, Septic, Hypotensive, Lactate
- Trial name
- NCT06727318
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people
- Sponsor
- Gulhane Training and Research Hospital
Ageing, Blood Flow Restriction
Comparing Vascular Responses to Resistance Exercise with and Without Blood Flow Restriction in Young and Older Adults
Aging leads to declines in functional capacity and effort tolerance. Muscle strength remains stable from ages 25 to 50 but declines significantly after age 60, affecting activities like stair climbing and walking, reducing…
- Trial name
- HOLD TIGHT (NCT06596304)
- Testing
- Low intensity-resistance training with lower limb blood flow restriction, High Intensity Resistance Training
- Where
- 2 sites in Portugal
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Chronic Heart Failure
Blood Flow Restriction Training in Chronic Heart Failure: an Effective Training Strategy?
The purpose of this current study proposal is to identify the potential physiological adaptations arising from a combined BFR+HIIT training intervention in CHF patients.
- Trial name
- BFR-CHF (NCT03342833)
- Testing
- Blood flow restriction
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- University of Leeds
Open Angle Glaucoma
Study on the Impact of Ocular Anesthetic Procedures in Ocular Blood Flow
Anaesthetic procedures in ophthalmology surgery have been a subject rapidly evolving in the past decades. When deciding for a retrobulbar block, the local injection of varying mixtures and volumes of fast-acting anesthetics (such…
- Trial name
- NCT01840215
- Where
- Belgium
- Volunteers
- 240 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Spinal Cord Injury, Blood Pressure
TSCS for Acute SCI
This project will focus on a novel approach to stabilizing blood pressure (BP) during inpatient rehabilitation after acute SCI. After SCI, people have unstable blood pressure, ranging from too low (orthostatic hypotension) to too…
- Conditions
- Acute Spinal Cord Injury, Blood Pressure, Hypotension
- Trial name
- NCT05305118
- Testing
- TSCS Mapping, Transcutaneous spinal cord stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dental Pulp Test
Diagnostic Device for the Assessment of Pulpal Blood Flow
The purpose of this study is to assess tooth health by using a pulse oximeter which measures the blood flow within the tooth. This method is not currently being used in dentistry.
- Trial name
- NCT03578549
- Testing
- Pulse Oximetry
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Neonatal Respiratory Distress
Effect of Antenatal Steroid on Pulmonary Artery Blood Flow
The aim of this study is to determine the effect of administering antenatal steroids in term fetuses on the blood flow in the fetal pulmonary artery, and to correlate these findings with clinical data obtained after birth…
- Trial name
- NCT02978976
- Testing
- Betamethasone, saline
- Where
- Egypt
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pruritus
Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick
To determine the effective dose and the time course, the dermal blood flow response to histamine will be evaluated at different doses (5 µg, 15 µg and 50 µg).
- Trial name
- NCT04399213
- Testing
- 50 µg Histamine, 15 µg Histamine, 5 µg Histamine
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Liver Failure, Liver Transplantation
Autoregulation Assessment During Liver Transplantation
Patients with liver failure undergoing liver transplantation often have clinical or sub-clinical encephalopathy that may lead to increased intracranial pressure.
- Conditions
- Liver Failure, Liver Transplantation, Encephalopathy
- Trial name
- NCT01425385
- Testing
- Near infrared spectroscopy monitoring, Autoregulation monitoring
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Central Serous Chorioretinopathy
Optical Coherence Tomography Angiography (OCT-A) and Central Serous Chorioretinopathy (CSC)
Optical Coherence Tomography Angiography (OCT-A) is a noninvasive imaging technique that allows one to see blood vessels in the retina.
- Trial name
- OPACITY (NCT03950089)
- Testing
- Optical Coherence Tomography Angiography (OCT-A)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Heart Failure
Interval Versus Continuous Training in Heart Failure
BACKGROUND: The physiopathology of the heart failure involves compensatory mechanisms as exacerbated neurohormonal activity, endothelial dysfunction and consequently the muscle disability and exercise intolerance.
- Trial name
- NCT02448147
- Testing
- Interval training, Continuous training
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
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