Clinical trials: Physical Function in Older Adults
Spinal Amyotrophy
SMAdult - Monitoring of Movement on Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is a rare neuromuscular disease causing progressive muscle weakness related to degeneration of motor neurons.
- Trial name
- SMAdult (NCT07894185)
- Testing
- wearable sensors
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Liege
Quality Indicators, Physical Disability
Impact of Educational and Professional Supportive Interventions on Nursing Home Quality Indicators
Introduction: Efficacy of audit and feedback interventions on nursing home (NH)quality indicators is not well-established. The main objective: The main purpose of the IQUARE study was to examine the impact of two types of audit…
- Trial name
- IQUARE (NCT01703689)
- Testing
- Audit and Feedback, Cooperative Work
- Where
- 175 sites in France
- Volunteers
- 8,039 people
- Sponsor
- Agence Régionale de la Santé - Midi Pyrénées
Neuromuscular Performance, Reaction Time
Effects of Virtual Reality Exergaming on Reaction Time, Physical Performance, and Muscle Activity in Children
This randomized controlled trial will investigate the immediate effects of virtual reality (VR) exergaming on reaction time, physical performance, balance, and muscle activity in children aged 10-14 years with different athletic…
- Conditions
- Neuromuscular Performance, Reaction Time, Postural Balance
- Trial name
- PED-VR-EMG (NCT07916155)
- Testing
- Immersive Virtual Reality Exergaming
- Where
- Romania
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Aging
Effects of Dance on Reaction Time in Experienced Older Adults
Aim of this study was to investigate the effects of 6-month ballroom dance (3 times/wk) on physical fitness and reaction time in twenty- four experienced older adults.
- Trial name
- NCT04680364
- Testing
- partnered dance
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Healthy, Pulmonary Function Test
Respiratory Oscillometry Norms for Polish Children and Adolescent.
This study aims to establish normative values for respiratory oscillometry in the Polish pediatric population. It is designed as a multicentre, population-based, prospective cohort study including children and adolescents aged…
- Trial name
- OSCILLONiCA-PL (NCT07207720)
- Where
- Poland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Diabetes Mellitus, Type 1
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
The purpose of this study is to find out if baricitinib can preserve beta-cell function in participants newly diagnosed with type 1 diabetes. Participation in the study will last about 60 weeks.
- Trial name
- NCT07222332
- Testing
- Baricitinib
- Where
- 130 sites in United States, Australia and 18 more
- Volunteers
- 300 people
- Sponsor
- Eli Lilly and Company
Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment
Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment
Mild and Moderate cognitive impairment is a condition characterized by a noticeable decline in cognitive abilities, including memory and thinking skills, which is greater than expected for an individual's age but does not…
- Trial name
- nill (NCT07775079)
- Testing
- Integrated Dual-Task Training, Sequential Dual-Task Training
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Walking Mesh
Smart Sock for Monitoring Walking and Supporting Physical Activity in Older Adults
The goal of this randomized feasibility clinical trial is to learn whether a low-cost smart sock and mobile application can be used safely, reliably, and comfortably to support gradual walking activity in adults aged 60 years and…
- Trial name
- NCT07902102
- Testing
- Low-Cost Smart Sock and Older-Adult Mobile Application, Standard Individual Walking Plan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Epilepsy, Epilepsia
Physical Exercise in Subjects With Juvenile Myoclonic Epilepsy
Epilepsy is a chronic neurologic disorder characterized by seizures. Beside seizures people suffering from epilepsy experience several challenges related to education, work and everyday life such as learning-, problem-solving…
- Conditions
- Epilepsy, Epilepsia, Epileptic Seizures, Seizure Disorder
- Trial name
- EFA (NCT01450423)
- Testing
- Physical activity
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Lars Bo Andersen
Wheezing
Montelukast in Children With Wheezing
In this study children with recurrent wheezing (>/= 2 episodes in the last 6 months)and aged less than 2 years will be enrolled as outpatients.
- Trial name
- NCT00775697
- Testing
- Montelukast
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Universita di Verona
Cystic Fibrosis
Backpack Carrying in Children With Cystic Fibrosis
Cystic Fibrosis is a hereditary, chronic respiratory illness. Cystic Fibrosis leads to a progressive decline in lung function. School-aged children with cystic fibrosis experience backpack carrying everyday.
- Trial name
- NCT02700282
- Testing
- Backpack Carrying
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier du Havre
Cerebral Palsy
Pilot Study on Breathing Exercises and Pulmonary Function in Children With Cerebral Palsy: A Randomized Trial
This pilot study is a randomized controlled trial aimed at investigating the efficacy of protocolized conductive breathing exercises combined with regular air ventilation, in addition to standard care, on various aspects of…
- Trial name
- NCT06840626
- Testing
- Series of breathing exercises
- Where
- Hungary
- Volunteers
- 55 people
- Sponsor
- Semmelweis University
Healthy Volunteers, Child Development
Play-Based Motor Training in Children Aged 7-10 Years
This randomized controlled study evaluated the effects of an 8-week structured play-based motor training program on motor competence in children (boys and girls) aged 7-10 years.
- Trial name
- PBMT-DC (NCT07771959)
- Testing
- Structured Play-Based Motor Training Program, Usual Physical Education
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Sleep Duration, Child Obesity
Effect of Sleep Extension on Body Weight and Learning in Children (More2Sleep)
More2Sleep is a randomized, controlled, parallel trial with two groups (sleep extension vs control) including 142 school-aged children (6-12 years) who have a BMI above average, defined as age- and sex-specific BMI Z-score above…
- Conditions
- Sleep Duration, Child Obesity, Child Development, Child Behavior
- Trial name
- More2Sleep (NCT06341179)
- Testing
- Sleep extension
- Where
- 3 sites in Denmark
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Asthma
Study of Dose-response to Bronchodilator and Dose-finding in Child 2.5 to 6 Years - Study Golden
In older children and adults, bronchodilator (BD) dose-effect relationship is part of the characteristics of asthma disease. There are no data on BD dose-response relationship in wheezy preschool children whose disease…
- Trial name
- DORESI (NCT01470755)
- Testing
- salbutamol, Salbutamol - dose2, Salbutamol -dose3
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Malaria, Asymptomatic Malaria
OPTIMAL LEAP: Optimizing Dihydroartemisinin-Piperaquine IPTsc Intervals to Advance Learning, Executive Function, Attendance, and Antimalarial Resistance Surveillance in Kenyan Schoolchildren
Malaria remains a major cause of illness among school-aged children in sub-Saharan Africa, many of whom carry asymptomatic Plasmodium falciparum infections that may contribute to anemia, inflammation, school absenteeism, and…
- Conditions
- Malaria, Asymptomatic Malaria, Intermittent Preventive Treatment
- Trial name
- Optimal LEAP (NCT07798583)
- Testing
- Monthly DP, Quarterly DP
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Indiana University
Bereavement, Depressive Disorder
Consequences of Conjugal Bereavement in Adults
Bereavement refers to the expected reactions and sadness associated with the loss of a loved one. It has been reported that the loss of a spouse is rated as the major life stressor among survivors of varying ages and diverse…
- Conditions
- Bereavement, Depressive Disorder, Immunologic Disease, Mental Disorder
- Trial name
- NCT00001659
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit Disorder With Hyperactivity
Single Versus Combination Medication Treatment for Children With Attention Deficit Hyperactivity Disorder
This study will evaluate the effectiveness of a single drug versus a combination of drugs in treating attention deficit hyperactivity disorder in children.
- Trial name
- Project1 (NCT00429273)
- Testing
- Guanfacine, Methylphenidate (MPH)
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- University of California, Los Angeles
Sarcopenia
Respiratory Sarcopenia in Older Adults
The objectives of this study are to describe the prevalence of respiratory sarcopenia, evaluate its pattern of evolution over a one-year follow-up, and determine the response to a therapeutic exercise program in older adults in a…
- Trial name
- NCT06548984
- Testing
- diaphragmatic exercises, Respiratory muscle training
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Felipe León Morillas
Cerebral Palsy
Upper Extremity Function, School Performance, and Academic Success in Children With Cerebral Palsy
The aim of this study is to investigate the relationship between upper extremity functionality and school-related outcomes, including academic achievement, school performance, and perceived academic success in school-aged…
- Trial name
- CP-SCHOOL (NCT07561710)
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Yeditepe University