Clinical trials: Physical Function in Older Adults
Conditions or Focus of Study: Cognitive Function Loneliness Aging Physical Activity
Wearable-Assisted Walking for Cognitive Function and Loneliness in Older Adults
Participants in the wearable-assisted walking group were asked to walk five days per week for approximately 30 minutes per session at moderate intensity.
- Trial name
- WAW-CogLon (NCT07650292)
- Testing
- Wearable-Assisted Walking Program
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan College of Performing Arts
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Frail Older Adults
CogXergaming to Promote Physical Activity and Cognitive Function in Frail Older Adults
Due to the age associated sarcopenia and reduced cardiovascular fitness, frail older adults experience significant decrease in physical function which comprises of mobility, endurance, muscle strength and balance control.
- Trial name
- NCT04534686
- Testing
- CogXergaming, Matter of Balance Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Illinois at Chicago
Cognition, Affect (Mental Function)
PRECOG Pilot Project
This pilot study aims to investigate the chronic effects of a prebiotic blend on cognitive, affective and gut microbiome outcomes in healthy adults aged 60-75 years.
- Conditions
- Cognition, Affect (Mental Function), Gut Microbiome
- Trial name
- NCT06911957
- Testing
- Prebiotic blend
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Reading
Cognitively Normal Older Adults, Hypertension
Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)
The purpose of this study is to determine if intensive lowering of systolic blood pressure (SBP), using FDA approved medications (antihypertensive), reduces Alzheimer's Disease pathology (i.e., excessive brain amyloid and tau…
- Conditions
- Cognitively Normal Older Adults, Hypertension, Subjective Cognitive Decline, Family History of Dementia
- Trial name
- IPAT (NCT05331144)
- Testing
- Angiotensin II Receptor Blockers (ARBs, losartan) and Calcium Channel Blockers (CCB, amlodipine), PCP
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Rong Zhang
Aging, Cognitive Dysfunction
Physical Activity and Cognitive Function in Older Adults: A Novel Role for GPLD1
The investigators are conducting a cross-sectional, observational study to investigate whether plasma GPLD1 concentrations are associated with higher cognitive function and better brain structure and function in two groups of…
- Trial name
- BrainFit (NCT04645134)
- Testing
- Brain Health Assessments
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Healthy Ageing
Exploring Blood Flow Restriction as an Accessible Fitness Solution for Healthy Aging in Seniors
As people age, it can become harder to stay active and independent, especially when dealing with fatigue, joint pain, or other health problems.
- Trial name
- NCT07460609
- Testing
- Blood Flow Restriction Training Exercise, Health Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor University
Neurocognitive Disorders, Inhalation; Vapor
Effect of Low Flow Anesthetics on Neurocognitive Decline in the Elderly
This study aims to investigate the effect of inhaled anesthetics with a low fresh gas flow on cognitive function of elderly patients undergoing elective surgery
- Trial name
- NCT05548998
- Testing
- General anesthesia with low fresh gas flow, General anesthesia with high fresh gas flow, Mini mental state examination
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Postoperative Cognitive Dysfunction, Acute Postoperative Pain
Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients
To investigate the effect of ultrasound-guided thoracic paravertebral nerve block on postoperative acute and chronic pain and cognitive function in elderly patients with thoracoscopic partial lung resection.
- Conditions
- Postoperative Cognitive Dysfunction, Acute Postoperative Pain, Chronic Postsurgical Pain
- Trial name
- NCT05364216
- Testing
- Measurement of cognitive function, Thoracic paravertebral block, The assessment of cognitive function
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Alzheimer Disease
An Objective Assessment Tool for Evaluating Functioning in Older Adults
The Investigators are seeking your consent to participate in research investigating the development of a mobile application that enhances physical and cognitive assessments.
- Trial name
- SPPB++ (NCT06489847)
- Testing
- SPPB++ Application
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
Frail Elderly
Effectiveness of a Program Using Video Games Associated With Conventional Physiotherapy in Physical Functioning in Frail Elderly Compared to Conventional Physiotherapy
Frailty is a highly prevalent condition, reaching approximately 7% to 30% of older adults aged from 65 up to 80 years [2]. Although exercises seemed to be beneficial for the frail elders, there is still insufficient evidence to…
- Trial name
- NCT02333214
- Testing
- Exergames and conventional physiotherapy, Conventional physiotherapy
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- Universidade Cidade de Sao Paulo
Executive Function of School-aged Children With ASD
VR Executive Training of School-aged Children With ASD
Many studies support that children with autism spectrum disorder (ASD) show executive dysfunction. The applicant's NSC project report also indicated that in all areas in the behavior rating inventory of executive function, the…
- Trial name
- NCT06130293
- Testing
- VR game intervention
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan Normal University
Metabolic Syndrome, Predisposition to Cardiovascular Disease
Analysis of the Postprandial Effects of a Vegetable Protein Mixture Rich in Arginine, Cysteine and Leucine on Endothelial Dysfunction and Inflammation at Low Noise in Elderly People With Cardiometabolic Risk
By 2050, the expanding world population will consume two-thirds more animal protein than it consumes today. The increase in chronic diseases associated with the generalization of these consumption patterns tend to understand the…
- Trial name
- P-PROBS CM (NCT04923555)
- Testing
- Vegetable proteins (VP) rich in leucine, cystein, arginine, Animal proteins (AP), No protein (T)
- Where
- France
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Gastrointestinal Microbiome (Focus), Gastrointestinal Symptoms
The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight
The study is a single-center, randomized, double-blind, placebo-controlled study in middle-aged to elderly adults with excessive body weight. The study includes an 8-week intervention period followed by a 2-week follow-up period.
- Trial name
- myBIOM (NCT07453823)
- Testing
- Synbiotic
- Where
- Ireland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chr Hansen - part of Novonesis
Aging
Effects of HIIT in Older Adults
This study investigated the effects of high-intensity interval training (HIIT) on functional fitness in older adults. As people age, they often experience a natural decline in physical abilities such as strength, flexibility…
- Trial name
- HIIT (NCT07170579)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 39 people
- Sponsor
- Instituto Politécnico de Bragança
Cognitive Impairment, Cardiovascular Risk Factor
The Active Mind Study
The purpose of this study is to explore whether physical exercise, mindfulness training, or both interventions together can improve cognitive function in individuals with multiple risk factors for the development of dementia in…
- Trial name
- NCT03289546
- Testing
- Mindfulness training, Aerobic training
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- The Miriam Hospital
Cognition Disorders
Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults
The aim of this project is to explore whether vision correction can effectively slow cognitive decline in older adults. The primary question it seeks to answer is: Can providing free near and/or distance vision correction glasses…
- Trial name
- CLEVER (NCT06836440)
- Testing
- Free Prescription Glasses
- Where
- China
- Volunteers
- 964 people, healthy volunteers welcome
- Sponsor
- Yuju Wu
Diabetes, Older People
Comprehensive Approach to Reduce Elderly Functional Decline in Diabetes: the CARED Study
Importance. Conventionally, treatment goals for diabetic patients primarily target glycemic levels and traditional cardiovascular risk factors (blood pressure, lipids) control to reduce macro- and micro-vascular complications.
- Trial name
- CARED (NCT06842459)
- Testing
- Geriatric Assessment
- Where
- 2 sites in Italy
- Volunteers
- 180 people
- Sponsor
- University of Cagliari
Older Adults
VR Gaming and Its Impact on Functional Status and Quality of Life in Seniors
This project examined the impact of virtual reality (VR)-based physical activity on the functional status and quality of life (QoL) of older residents in a nursing home.
- Trial name
- NCT06864325
- Testing
- VR-training
- Where
- 2 sites in Poland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Cognitive Decline, Aging
Effects of Comprehensive Community Support Programs on Cognitive Function and Quality of Life in Older Adults
This prospective observational study aims to investigate the effects of a multidomain community-based support program on cognitive function and quality of life in older adults attending the Vefahane Life Center in Istanbul…
- Conditions
- Cognitive Decline, Aging, Quality of Life
- Trial name
- NCT07610109
- Testing
- Multidomain Community Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
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