Clinical trials: Platelet-rich Fibrin
Odontogenic Maxillary Cysts
Effect of Biphasic Bone Graft Material With Autologous Platelet-rich Fibrin on Bone Regeneration in a Maxillary Cyst
Effect of Biphasic Bone Graft Material (BGM) in combination with autologous platelet-rich fibrin (PRF) on bone regeneration in an odontogenic maxillary cyst: a randomized clinical trial
- Trial name
- NCT03003013
- Testing
- Biphasic Bone Graft Material (BGM) in Combination With Autologous Platelet-rich Fibrin (PRF)
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Diabetic Foot Ulcers, Diabetic Wound
The Effect of Combination Therapy of Oral MB and PRP-FG in Patients With Non-healing Diabetic Foot Ulcer
The aim of this study is to evaluate the chance of non-healing diabetic foot ulcers repair by improving the condition of lack of oxygen or hypoxia in the wound area caused by diabetes using methylene blue along with the use of…
- Trial name
- NCT05850611
- Testing
- Methylene Blue, Milk (control), Methylene Blue and Platelet-Rich Plasma-Fibrin Glue
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Periapical Periodontitis
Endodontic Microsurgery With the Use of L-PRF and an Occlusive Membrane: a Randomized Controlled Clinical Trial
This study evaluates the effect of leucocyte and platelet rich fibrin (L-PRF) during endodontic microsurgery (EMS) on patient's post-operative comfort and periapical bone healing.
- Trial name
- NCT02528240
- Testing
- EMS, + occlusive membrane, conebeam CT
- Where
- Belgium
- Volunteers
- 56 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Necrotic Pulp
Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates
Injectable platelet-rich fibrin (I-PRF) is a flowable blood concentrate that is entirely natural and allows ease of access and flow within the root canal. It was first developed in 2014 by modifying the centrifugation parameters.
- Trial name
- NCT03698188
- Testing
- Injectable platelet-rich fibrin, Platelet-rich plasma
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Impacted Third Molar Tooth
Comperasion the Postoperative Effect of Low Laser Therapy and Platelet Rich Fibrin on Mandibular Third Molar Surgery.
The aim of this study was investigate the comparison of postoperative effects of low laser treatment and platelet-rich fibrin application on mandibular impacted third molar tooth extraction.
- Trial name
- NCT06262945
- Testing
- Diagnoses, traditional osteotomies, platelet rich fibrin
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beste Erismen
Cleft Palate, Unilateral Cleft Palate
Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate
This prospective, randomized controlled trial evaluates the clinical efficacy of autologous Platelet-Rich Fibrin (PRF) and Gentamicin-Loaded PRF as regenerative and antimicrobial biological adjuncts in primary palatoplasty.
- Conditions
- Cleft Palate, Unilateral Cleft Palate, Bilateral Cleft Palate, Complete Cleft Palat
- Trial name
- NCT07752849
- Testing
- Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF
- Where
- Yemen
- Volunteers
- 90 people
- Sponsor
- Al-Thawra Modern General Hospital
Interdental Papilla Reconstruction, Deficient Interdental Papilla
Treatment of Deficient Interdental Papilla Using Albumin-platelets Rich Fibrin
The goal of this ( A case series, clinical trial ) is treatment of deficient interdental papilla in patients who have interdental papillary loss class 1 or 2 in maxillary or mandibular anterior region with plaque index and…
- Trial name
- A case series (NCT06842277)
- Testing
- Injectable albumin platelets rich fibrin
- Where
- 2 sites in Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Effects of; Movement of Teeth Assiste Wit MOPS and I-prf
Maxillary Canine Retraction Assisted With Micro-osteoperforations Versus Injectable Platelet Rich Fibrin
The present clinical comparative study will be undertaken for assessment of two different modalities of maxillary canine retraction assisted with microosteoperforations versus injectable platelet rich fibrin.
- Trial name
- NCT05960825
- Testing
- injectable platelet rich fibrin versus microosteoperforation
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Effect of Platelet Rich FibrinDuring Clear Aligner Therapy
Influence of Injectable Platelet Rich Fibrin on Different Orthodontic Tooth Movements During Clear Aligner Therapy
The aim of this prospective clinical project will be to assess the effect of platelet rich fibrin on the rate of different orthodontic tooth movements during clear aligner therapy.
- Trial name
- NCT06380946
- Testing
- iPRF
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Distal Hypospadias, Hypospadias
Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias
Hypospadias is a common congenital condition in boys in which the opening of the urethra is located on the underside of the penis.
- Trial name
- FTIP-RCT (NCT07319780)
- Testing
- Fibrin-Enhanced TIP Urethroplasty, Grafted TIP Urethroplasty
- Where
- 2 sites in Indonesia, Uzbekistan
- Volunteers
- 100 people
- Sponsor
- National Children's Medical Center, Uzbekistan
Periodontal Bone Loss
Evaluation of the Effect of Incorporation of Vitamin C Into Platelet Rich Fibrin Scaffold in Treatment of Intra-osseous Periodontal Defects
This study is meant to assess clinically the possible predictable clinical attachment gain regarding the use of vitamin C with platelet rich fibrin versus platelet rich fibrin alone in the treatment of periodontal intrabony…
- Trial name
- NCT03707483
- Testing
- combination of vitamin C and platelet rich fibrin
- Volunteers
- 20 people
- Sponsor
- Cairo University
Pulpitis - Irreversible, Tooth Decay
Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth
Of all the various pulpotomy medicaments that have been studied till to date, three agents have been selected for this study to compare their efficacy.
- Trial name
- NCT05266859
- Testing
- Calcium hydroxide, MTA, PRF
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Liaquat College of Medicine and Dentistry
Injectable Platelet Rich Fibrin and Microneedling in Papilla Reconstruction, Interdental Papillae Reconstruction
Injectable Platelet-Rich Fibrin and Microneedling For Papillae Reconstruction In Esthetic Zone
The currently available non-surgical techniques for papillary reconstruction did not provide long term maintenance of papillary regeneration, Surgical techniques are invasive and the results are unpredictable .
- Trial name
- iPRFandMN (NCT06021301)
- Testing
- Platelet-Rich Fibrin and Microneedling
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lateral Sinus Lifting
Lateral Sinus Augmentation Utilizing Bovine Bone Mixed with Platelet-rich Fibrin
Background: In sinus augmentation procedure, graft resorption remains a major dilemma of various graft materials. Objective: To estimate the graft volume changes following lateral sinus augmentation utilizing cone beam computed…
- Trial name
- NCT06810921
- Testing
- lateral sinus lift
- Where
- Iraq
- Volunteers
- 34 people
- Sponsor
- University of Baghdad
Gingival Pigmentation
Effect of Injectable Platelet Rich Fibrin on Healing and Patient Satisfaction Following Laser Gingival Depigmentation
The objectives of the present study are to: 1. Evaluate the effect of I-PRF injection following laser gingival depigmentation technique on the healing period as a primary objective. 2.
- Trial name
- NCT05283668
- Testing
- i-PRF, Diode Laser
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Ain Shams University
Chronic Apical Periodontitis, Pulp Necrosis
Clinical and Inflammatory Outcomes of Regenerative Endodontic Treatment Using Injectable Platelet-Rich Fibrin in Mature Necrotic Teeth With Chronic Apical Periodontitis.
This randomized clinical trial aims to compare regenerative endodontic treatment using injectable platelet-rich fibrin (i-PRF) with conventional root canal treatment in mature necrotic anterior teeth with chronic apical…
- Trial name
- REGEN-iPRF (NCT07913399)
- Testing
- Conventional Root Canal Treatment, Regenerative Endodontic Treatment with i-PRF, Injectable Platelet-Rich Fibrin (i-PRF)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Hypospadias
Efficacy of PRF in Hypospadias Repair
Hypospadias is an anomaly characterized by an ectopic ventral urethral meatus, and an incomplete or hooded prepuce. Its incidence is estimated at 1 in 200-300 live male births, with variations across populations and severity…
- Trial name
- NCT07757828
- Testing
- Tubularized Incised Plate urethroplasty with intraoperative placement of autologous PRF onto the urethral plate., standard Tubularized Incised Plate urethroplasty
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Revascularization of Immature Young Permenant Teeth
Compare Between the Effect of CGF and PRF on Revascularization of Immature Roots of the Mandibular Permanent First Molar
in this study investigators do revascularization technique to promote root growth of immature mandibular first permanent molar by using CGF and PRF from blood sample of patients
- Trial name
- NCT07460869
- Testing
- Revascularization/Conservative management
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Impacted Wisdom Tooth, Pain
Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo
The aim of this study was investigate the effectiveness of Local Antibiotic Applications With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo and In Vitro.
- Conditions
- Impacted Wisdom Tooth, Pain, Staphylococcus Aureus
- Trial name
- NCT05678296
- Testing
- Diagnosis, Analgesic, traditional osteotomies
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Effect of Platelet Rich Fibrin Versus Microosteoperforation Compaed to Control Group Toothmovement
Assessment of the Efficacy of Microosteoperforations Versus Injectable Platelet-rich Fibrin During Orthodontic Leveling and Alignment of Mandibular Incisors
The aim of this prospective clinical study will be to compare the efficacy of micro osteoperforations versus injectable platelet-rich fibrin during orthodontic leveling and alignment of mandibular incisors.
- Trial name
- NCT06498609
- Testing
- iprf, MOPs with leveling and alignment
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University