Clinical trials: Positive Affect
Attentional Bias, Smoking Cues
Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents
This research aims to investigate how exposure to advertising for Electronic Nicotine Delivery Systems (commonly called e-cigarettes) may lead to combustible smoking initiation in adolescents.
- Conditions
- Attentional Bias, Smoking Cues, Positive Perceptions About Cigarette Smoking, Social Norms
- Trial name
- NCT03786042
- Testing
- E-cigarette ad exposure, non e-cigarette TV commercials
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Trustees of Dartmouth College
Help-Seeking Behavior, Emotions
Mobile Phone Intervention to Reduce Youth Suicide in Rural Communities
The goal of this research project is to conduct a pilot RCT of Text4Strength, an interactive automated text messaging extension of Sources of Strength (SoS), a universal school-based suicide prevention program that prepares…
- Conditions
- Help-Seeking Behavior, Emotions, Trusted Adults, Suicide
- Trial name
- NCT03145363
- Testing
- Intervention, Control
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Adolescent Behavior, Stress Reduction
CEDARS Intervention: A Coping, Emotional Development, & Stress Reduction Intervention
Using an adapted stress-reduction intervention called the CEDARS, the investigators will pilot the intervention in adolescents (N=40) to determine the feasibility and acceptability of CEDARS implementation and to investigate…
- Conditions
- Adolescent Behavior, Stress Reduction, Adverse Childhood Experiences, Positive Attitude
- Trial name
- CEDARS (NCT04958694)
- Testing
- CEDARS
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
People Living With HIV
A Hybrid Type II Trial of the Optimizing Resilience and Coping With HIV Through Internet Delivery in Ryan White Clinics in Chicago
Among people living with HIV (PLWH), positive affect is uniquely associated with lower levels of depression, slower disease progression, better adherence to medication, and higher likelihood of achieving suppressed viral load…
- Trial name
- ORCHID (NCT05123144)
- Testing
- BHS+ORCHID
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- Northwestern University
Emotional Distress, Anhedonia
Positive Events Training to Enhance Positive Emotions in Adolescents With Elevated Depressive Symptoms: An N=1 Trial
Research shows that high positive emotionality is an essential ingredient in building resilience in youngsters, especially those with a vulnerability to develop depressive symptomatology.
- Trial name
- iPET N=1 (NCT07825285)
- Testing
- Positive Events Training (PET)
- Where
- Belgium
- Volunteers
- 1 people
- Sponsor
- KU Leuven
Happiness, Self Efficacy
Strengths to Grow: An Online Parenting Resource
Research suggests that strength-based parenting programs can enhance family well-being, but the current formats of these programs (e.g., in-person workshops) are not accessible to many families.
- Conditions
- Happiness, Self Efficacy, Positive Affect
- Trial name
- NCT05535881
- Testing
- Strengths to Grow Program
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Suicidal Ideation, Suicide, Attempted
Skills to Enhance Positive Affect in Suicidal Adolescents
The prevalence of suicidal behaviors in adolescents remains unacceptably high and is a significant public health concern. The investigators propose a new treatment approach in which skills to increase positive emotions are taught…
- Trial name
- STEP (NCT02130583)
- Testing
- Positive Affect Skills Training, Treatment as Usual
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Brown University
Alcoholism, Healthy
The Effect of Positive and Negative Emotions on Brain Activity in Alcoholics and Nonalcoholics
This study was designed to learn more about the areas of the brain involved in the experience of positive and negative emotions.
- Trial name
- NCT00001675
- Where
- United States
- Volunteers
- 1,194 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Influenza Like Illness, Asthma
How Does the Clinical Tool 'What's Going Around' Affect Clinical Practice
Previous work has shown that the epidemiological context of a patient's presentation can provide important information for clinicians to aid in diagnosis and treatment.
- Conditions
- Influenza Like Illness, Asthma, Group A Streptococcal Infection, Pertussis
- Trial name
- WGA (NCT01979588)
- Testing
- What's Going Around tool, Control
- Where
- United States
- Volunteers
- 206,703 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
HIV/AIDS
Does Provision of Point of Care CD4 Technology and Early Knowledge of CD4 Levels Affect Early Initiation and Retention on Anti-retroviral Treatment (ART) in HIV Positive Pregnant Women in the Context of Option B+ for PMTCT?
The study will be conducted at 32 health care facilities in three provinces in Zimbabwe and will compare the impact of the provision Point of Care CD4 technology and early knowledge of CD4 levels on retention at 12 months, with…
- Trial name
- E4E (NCT02070900)
- Testing
- POC CD4, Programmatic Mentoring
- Where
- 32 sites in Zimbabwe
- Volunteers
- 704 people, healthy volunteers welcome
- Sponsor
- WHO, Department of Maternal, Newborn, Child and Adolescent Health
Autism Spectrum Disorder
Social ABCs for Toddlers With Signs of Autism Spectrum Disorder: Trial of a Parent-Mediated Intervention
The Social ABCs is an innovative parent-mediated intervention for toddlers with confirmed or suspected Autism Spectrum Disorder (ASD).
- Trial name
- NCT02428452
- Testing
- Social ABCs parent-mediated intervention program
- Where
- 2 sites in Canada
- Volunteers
- 63 people
- Sponsor
- Jessica Brian
Cancer
Emotion Regulation and Pain in Children With Cancer
This study tested the effects of emotion regulation strategies (reappraisal, reassurance, and empathy) on pain responses in children with cancer.
- Trial name
- NCT03133507
- Testing
- Reapprasial Condition, Reassurance Condition, Distraction Condition
- Volunteers
- 73 people
- Sponsor
- University of California, Irvine
Emotional Distress, Anhedonia
Promoting Positive Emotions in Adolescents Using Positive Events Training: An Indicated Approach
Research shows that high positive emotionality is an essential ingredient in building resilience in youngsters, especially those with a vulnerability to develop depressive symptomatology.
- Trial name
- iPET (NCT07288541)
- Testing
- Positive Events Training (PET)
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- KU Leuven
Type 1 Diabetes Mellitus (T1DM), Anxiety
Drawing and Writing Activities in Adolescents With Type 1 Diabetes
This randomized controlled trial aims to evaluate the effects of drawing and writing activities on anxiety and positive and negative affect in adolescents with type 1 diabetes.
- Trial name
- NCT07830082
- Testing
- Drawing and Writing Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Gazi University
Social Skills, Perfectionism
Effectiveness of the Universal Prevention Program Super Skills for Life in Schools
This study aims to evaluate the effectiveness of a 12-session cognitive-behavioral transdiagnostic protocol for Spanish children aged 8 to 12 within an educational context, Super Skills for Life.
- Conditions
- Social Skills, Perfectionism, Self Esteem, Positive Affect
- Trial name
- NCT06444581
- Testing
- Super Skills Schools
- Where
- Spain
- Volunteers
- 1,100 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Depression
Positive Affect Treatment for Adolescents With Early Life Adversity
Youth exposed to early life adversity (ELA) are known to be at greater risk for depression and suicidality and account for almost half of the youth suffering from psychiatric diseases today.
- Trial name
- PAT4ELA (NCT06273137)
- Testing
- Positive affect treatment, Supportive psychotherapy (SUP)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Technology Use, Positive Affect
Best Possible Self-Tech for Middle Schoolers
The goal of this pilot clinical trial is to learn if a single-session writing exercise (i.e., Best Possible Self-Tech) can improve positive affect and prosocial technology use in a community sample of eighth graders.
- Trial name
- NCT07540819
- Testing
- Best Possible Self-Tech
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Major Depressive Disorder
VR-Moodboost; an Innovative Virtual Reality Treatment for Adolescents With Depression
Major depressive disorder (MDD) is a prevalent and disabling mental health condition. A recent meta-analysis shows that across all forms of psychotherapy, only 43% of all depressive patients fully recover from MDD and relapse…
- Trial name
- VR-Moodboost (NCT05486676)
- Testing
- VR-Moodboost; a Virtual Reality intervention for depression to enhance positive affect and reduce depressive symptoms.
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Claudi Bockting
Mental Health Wellness 1, Positive and Negative Affect
Effects of a Relaxation and Guided Imagery Intervention in School Context
Specific aims - To test the effects of a relaxation and guided imagery intervention with socioemotional learning content on a range of socioemotional, physiological, cognitive and academic outcomes of school-aged children…
- Conditions
- Mental Health Wellness 1, Positive and Negative Affect, Social Skills, Happiness
- Trial name
- MR (NCT06101225)
- Testing
- MindRegulation Intervention, Relaxation, Waiting List Control Group
- Where
- Portugal
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universidade Autónoma de Lisboa
Depression, Parent-Child Relations
Parent Encouragement And Coaching of Happiness in Youth
The goal of this mechanistic clinical trial is to examine whether parent-coaching aimed at increasing child positive affect will increase child neural response to reward. The main questions it aims to answer are: Aim 1.
- Trial name
- PEACHY (NCT06725160)
- Testing
- Parent Coaching, Active Control
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh