Clinical trials: Post Operative Analgesia
Conscious Sedation, Postoperative Analgesia
Analgo-Sedative Effects Of Oral, Or Nebulized Ketamine In Pre-schoolers Undergoing Elective Surgery.
the primary objective of this study is to investigate the sedative, and analgesic effects of oral, or nebulized ketamine as premedication drugs, and providing postoperative analgesia for the preschoolers and decrease their need…
- Trial name
- NCT03885427
- Testing
- Ketamine
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pain, Postoperative, Postoperative Pain, Acute
Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries
This is a double-arm randomized control trial evaluating the impact of preoperative opioid-free analgesia on time to trial of void in ambulatory urogynecologic surgeries.
- Trial name
- NCT06379425
- Testing
- Acetaminophen, Celecoxib, Gabapentin
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Dental Caries in Children, Wound Heal
Biostimulation After Tooth Extraction
This study evaluated the effect of low-level laser therapy on postoperative pain and wound healing in children undergoing primary molar extractions 40children, 6-10 years of age, systemically healthy, and had atraumatic…
- Trial name
- NCT06018584
- Testing
- Tooth extraction
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hazal Özer
Patients With Cryptorchism Who Are Planning to Undergo Orchiopexy
Does Low Dose of Dexamethasone Enhance Analgesic Quality of Caudal Analgesia in Children Undergoing Orchiopexy?
Caudal block is one of the most effective modalities to reduce pain both during and after the surgery involving areas under the umbilicus.
- Trial name
- NCT04841018
- Testing
- High dose dexamethasone, Low dose dexamethasone
- Where
- South Korea
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Analgesia
Analgesic Efficiency of Pudendal Nerve Block Versus Penil Block for Circumsion in Children
The aim of this prospective randomized study is to assess the analgesic efficacy of Pudendal block compared with penil block for pediatric patients undergoing circumsion concerning postoperative analgesic consumption within 24…
- Trial name
- NCT03258255
- Testing
- penil or pudendal nerve block in circumcision
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Fracture, Pain
Ibuprofen Versus Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?
For simple fractures treated in the emergency department with cast immobilisation only, ibuprofen has been shown to be superior to, or a least or equivalent to codeine with less side effects.
- Trial name
- NCT01605240
- Testing
- Acetaminophen and Ibuprofen, Acetaminophen and Codeine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Lower Limb Injury
Multimodal Analgesia Versus Peripheral Nerve Block for Postoperative Pain Management After Lower Limb Injury Surgery
The purpose of this clinical trial is to understand the effectiveness of femoral nerve block, combined sciatic and femoral nerve block, lumbar plexus block, epidural block, and intravenous analgesia pump in the application of…
- Trial name
- NCT06779968
- Testing
- Femoral Nerve Block, Combined Sciatic and Femoral Nerve Block, Lumbar plexus block
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xiaguang Duan
Postoperative Pain
Quadratus Lumborum Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Children
The aim of the present study is to evaluate and compare the analgesic effect of ultrasound-guided Quadratus Lumborum Block with ultrasound-guided Transversus Abdominis plane block in pediatric Laparoscopic lower abdominal…
- Trial name
- NCT04552548
- Testing
- regional nerve block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Spinal Fusion
Virtual Reality for Post-operative Pain Management
Use a randomized controlled trial (RCT) study design to measure pain experience, medication use, medical side effects, and length of hospital stay with and without availability of VR following spine fusion surgery
- Trial name
- NCT03584776
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Gillette Children's Specialty Healthcare
Circumcision, Lower Abdominal Surgery
Comparison of Caudal Block and Erector Spinae Block for Postoperative Analgesia
Caudal block (CB), a regional anesthesia technique, is the most commonly used neuraxial block method for postoperative pain control in sub-umbilical surgeries in children.
- Trial name
- NCT05284734
- Testing
- Regional anesthesia intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Tonsillitis, Obstructive Sleep Apnea of Child
Steroids and Pain Control After Tonsillectomy
This research study aims to find out if a single oral dose of steroid after tonsillectomy will reduce pain and decrease the need for narcotic medications.
- Trial name
- NCT03995628
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Medical University of South Carolina
Postoperative Pain, Rotator Cuff Injuries
US-Guided Preemptive Brachial Plexus Blockade May Reduce Post-operative Pain: a Randomized Study
Intense e recurrent nociceptive stimulation, which occurs in the postoperatively, can trigger sensitization of the peripheral and central nociceptive pathway, leading to chronic pain.
- Trial name
- NCT04005534
- Testing
- Standard group, Preemptive group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- University of Sao Paulo General Hospital
Abdominoplasty, Postoperative Pain
Comparison of the Efficacy of Transversus Abdominis Plane Block and Erector Spinae Plane Block in Postoperative Analgesia Management After Abdominoplasty
Introduction: Abdominoplasty involves the removal of excess skin and fat from the abdominal region, rectus sheath plication, and umbilical transposition.
- Conditions
- Abdominoplasty, Postoperative Pain, Transversus Abdominis Plane (TAP) Block, Erector Spinae Plane Block
- Trial name
- NCT06845215
- Testing
- Transversus abdominis plane (TAP) block, Erector spina plane block (ESP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Hypospadias, Pudendal Nerve Block
Ultrasound-Guided Pudendal vs Dorsal Penile Nerve Block for Pediatric Hypospadias Surgery
The goal of this clinical trial is to compare the effectiveness and safety of two regional anesthesia techniques, ultrasound-guided pudendal nerve block and dorsal penile nerve block, for postoperative pain management in children…
- Conditions
- Hypospadias, Pudendal Nerve Block, Penile Nerve Block, Postoperative Pain
- Trial name
- NCT07575204
- Testing
- Ultrasound-Guided Pudendal Nerve Block, Ultrasound-Guided Dorsal Penile Nerve Block
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Hypospadias Repair Surgery
Comparison of the Efficacy of Bupivacaine with and Without Dexmedetomidine As an Adjuvant on Penile Block for Postoperative Pain Relief in Pediatrics Undergoing Hypospadias Repair Surgery
The main issue with pain management in children especially young children is the difficulty involved in evaluating it. When a patient's level of pain cannot be accurately assessed, effective analgesia cannot be prescribed.
- Trial name
- NCT06789393
- Testing
- Dexmedetomidine, Bupivacaine
- Volunteers
- 80 people
- Sponsor
- Assiut University
Cleft Lip Palate, Orofacial Cleft
Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft Surgery
Orofacial clefts are among the most common congenital malformations, affecting approximately 1 in 700-1500 live births worldwide.
- Conditions
- Cleft Lip Palate, Orofacial Cleft, Agitation, Emergence, Analgesia Assessment
- Trial name
- NCT07557576
- Testing
- Ketamine (1 mg/kg), Dexmedetomidine (1-0,8-0,6-0,4 mcg/kg/h), Fentanyl 5 mcg/kg
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Iva Smiljanić
Adolescent Idiopathic Scoliosis, Analgesia
Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery
This is a single-center study comparing the effect of intravenous (IV) Lignocaine given throughout posterior spinal fusion surgery on the reduction of morphine usage during postoperative period in adolescent idiopathic scoliosis…
- Trial name
- IGNITE-AIS (NCT04931433)
- Testing
- Lignocaine, Normal saline
- Where
- Malaysia
- Volunteers
- 115 people
- Sponsor
- University of Malaya
Postoperative Pain Management
Escalating Ketamine Doses and Pre-emption
Ketamine affects postoperative pain when administered intravenously immediately before, during or at the end of surgical procedures.
- Trial name
- NCT01070108
- Testing
- Ketamine
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain
SPRIX in 0 to 11 Year-Old Patients Undergoing Open Surgical Procedures
The purpose of this study is to evaluate the pharmacokinetics and safety of postoperative administration of SPRIX in pediatric patients (ages 0-11) undergoing open surgical procedures.
- Trial name
- NCT02102516
- Testing
- SPRIX(intranasal ketorolac tromethamine)
- Where
- 4 sites in Poland
- Volunteers
- 45 people
- Sponsor
- Egalet Ltd
Effect of Drug, Complication of Treatment
Dexmedetomidine as a Sole Premedication for BMT Placement
There is very little evidence or research documenting any single method of sedation/analgesia for myringotomy tube (BMT) placement as being more effective than others.
- Trial name
- BMT (NCT05903326)
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Nemours Children's Clinic