Clinical trials: Post Operative Complications
Postoperative Pain
Transversus Abdominis Plane Blocks for Infants and Children for Postoperative Pain Control
After undergoing hernia surgery, hydrocelectomy or lower abdominal surgery, a child may experience some amount of pain in the post-operative period.
- Trial name
- NCT01559740
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pain, Postoperative
Ultrasonography for Confirmation of Caudal Injection
The purpose of our study is to evaluate whether utilizing ultrasound assessment during caudal epidural injection can reliably identify unrecognized and unsuccessful nerve blocks during the procedure, guide proper technique, and…
- Trial name
- NCT02321787
- Testing
- Ultrasound for confirmation of successful caudal block
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Endometritis, Wound Infection
Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
The Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) study is a large pragmatic multi-center randomized clinical trial designed to evaluate the comparative effectiveness and safety of azithromycin-based extended-spectrum…
- Conditions
- Endometritis, Wound Infection, Abscess, Surgical Site Infection
- Trial name
- C/SOAP (NCT01235546)
- Testing
- Azithromycin and standard of care
- Where
- 9 sites in United States
- Volunteers
- 2,013 people
- Sponsor
- Alan Tita
Arthroplasty Complications
Correlation of Intramedullary Pressure and Systemic Inflammatory Parameters in Cemented Femoral Stem
The cemented femoral stem have impact on increase on systemic parameters. Evaluation of the level of histamine, C-reactive protein (CRP) and leukocytes formula, IL1b, TNF alpha, IL6 and the reflection of changes of these…
- Trial name
- NCT04913623
- Testing
- Hip Replacement
- Where
- Kosovo
- Volunteers
- 60 people
- Sponsor
- University Clinical Centre of Kosova
Surgical Site Infection
Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors
Objective: To investigate if the use of the newly designed Alexis O Retractor leads to improved intra-operative and post-operative surgical outcomes in the setting of planned elective Caesarean Sections.
- Trial name
- NCT02685696
- Testing
- Alexis O Retractor, Metal Retractor
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Neuropathy, Phantom Limb Pain
Immersive Virtual Reality for Neuropathic Pain
Investigating how neuropathic limb pain, including phantom limb pain or complex regional pain syndrome, is affected by virtual reality.
- Conditions
- Neuropathy, Phantom Limb Pain, Complex Regional Pain Syndromes, Neuropathic Pain
- Trial name
- NCT03203772
- Testing
- Immersive Virtual Reality
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Loma Linda University
Pain, Postoperative
Safety and Efficacy of Cocktail Periarticular Injection in Simultaneous Total Knee Arthroplasty
We investigated the safety and efficacy of the bilateral periarticular cocktail injection at a reduced dosage in patients undergoing simultaneous bilateral total knee arthroplasty.
- Trial name
- NCT02270437
- Testing
- ropivacaine, fentanyl, adrenaline
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking Union Medical College Hospital
Sedation, Emergence Delirium
Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate
To compare the efficacy of the pre-operative nebulization of a combination of dexmedetomidine and ketamine versus nebulization of dexmedetomidine alone for sedation and prevention of emergence delirium in children undergoing…
- Trial name
- NCT05821972
- Testing
- Nebulization of dexmedetomidine and ketamine, Nebulization of dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
PONV, BIS
Effect of BIS-Guided Anesthesia on Postoperative Nausea and Vomiting in Pediatric Patients
This randomized controlled trial will evaluate the effect of bispectral index (BIS)-guided anesthesia on postoperative nausea and vomiting (PONV) in children aged 3-8 years undergoing elective adenoidectomy.
- Trial name
- NCT07189845
- Testing
- BIS GROUP, CONTROL GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Engin Çetin
Short Bowel Syndrome, Intestinal Failure
Can SMOFlipid®, A Composite Parenteral Nutrition Lipid Emulsion, Prevent Progression Of Parenteral Nutrition Associated Liver Disease In Infants?
The aim of this study is to determine the feasibility of conducting a trial to examine the efficacy of an ω3FA (Omega-3 fatty acid) containing balanced lipid emulsion in the prevention of progression of PNALD in infants with…
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Gastrointestinal Motility Disorder, Mucosal Enteropathy
- Trial name
- NCT00793195
- Testing
- Intralipid 20%, SMOFlipid 20%
- Where
- 5 sites in Canada
- Volunteers
- 24 people
- Sponsor
- The Hospital for Sick Children
Pain, Postoperative
Percutaneous Rectus Sheath Block Versus Intra-operative Rectus Sheath Block for Pediatric Umbilical Hernia Repair
This is a prospective, double-blinded, randomized controlled study comparing the efficacy of pre-incisional percutaneous rectus sheath block to intra-operative rectus sheath block under direct visualization prior to closure of…
- Trial name
- NCT02341144
- Testing
- Pre-op percutaneous rectus sheath block, Intra-operative rectus sheath block, Ropivacaine
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Johns Hopkins All Children's Hospital
Tonsillectomy, Child
The CMCPCTH Research in Chinese Children
To obtain hemorrhage rate after coblation tonsillectomy, and to investigate risk factors of hemorrhage after coblation tonsillectomy in children.
- Conditions
- Tonsillectomy, Child, Postoperative Hemorrhage
- Trial name
- NCT05206799
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- Shanghai Children's Hospital
Abdominal Aortic Aneurysm
Vasovist Endoleak Study
After endovascular treatment of an abdominal aortic aneurysm, lifelong imaging follow-up is needed to monitor the effectiveness of the treatment.
- Trial name
- NCT00483665
- Testing
- Computed tomography angiography, Magnetic resonance imaging
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- UMC Utrecht
Appendicitis, Surgical Wound Infection
Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)
The goal of this clinical trial is to compare primary wound closure (PC) versus delayed primary closure (DPC) after standardized wound decontamination using the High-Efficiency Incision and Drainage with Irrigation (HIEDI)…
- Conditions
- Appendicitis, Surgical Wound Infection, Postoperative Complications, Wound Healing
- Trial name
- HIEDI-Yemen (NCT07688109)
- Testing
- Primary Closure with HIEDI, Delayed Primary Closure with HIEDI
- Where
- 3 sites in Yemen
- Volunteers
- 200 people
- Sponsor
- Sana'a University
Surgical Site Infection
A Stratified, Multi-ARm, muLti-site Randomised Platform Trial Aiming to Reduce the INcidence of Post-operative SSI
MARLIN is a stratified, multi-arm, multi-stage factorial randomised platform trial aiming to reduce the incidence of post-operative surgical site infection (SSI).
- Trial name
- MARLIN (NCT06465901)
- Testing
- Chlorhexidine Gluconate 2.0% to 4.0% (e.g. Hibiscrub) preoperative shower, Intraoperative wound wash (e.g. Granudacyn), DACC surgical wound dressing (e.g. Leukomed Sorbact)
- Where
- 7 sites in Benin, Ghana and 5 more
- Volunteers
- 10,092 people
- Sponsor
- University of Birmingham
Short Bowel Syndrome
Amino Acid-based Oral Rehydration Solution in Children With Short Bowel Syndrome
This study will assess the tolerability and palatability of an amino acid based oral rehydration solution (enterade®) compared to current oral rehydration solution among children with short bowel syndrome .
- Trial name
- NCT03105362
- Testing
- Enterade® oral rehydration solution
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston Children's Hospital
Parents, Anxiety
Parental Anxiety and Postoperative Pain and Complications in Children Undergoing Tonsillectomy ± Adenoidectomy
It is aimed to understand whether high parental anxiety leads to increased pain in children undergoing tonsillectomy ± adenoidectomy surgery and whether it increases the development of complications.
- Conditions
- Parents, Anxiety, Complication of Surgical Procedure, Pain
- Trial name
- NCT06579586
- Testing
- Survey study
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Sumeyra DOLUOGLU
Anxiety, Postoperative Pain
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Dental Treatment
Dexmedetomidine is a drug known for its pain-relieving and restlessness-reducing effects. The purpose of this run is to use the association between this use during surgery and the attrition of post-operative pain and discomfort.
- Conditions
- Anxiety, Postoperative Pain, Nausea
- Trial name
- NCT06097169
- Testing
- Fentanyl, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Medipol University
Surgery, Covid19
GlobalSurg-CovidSurg Week
Observational study to determine the optimal timing for surgery following SARS-CoV-2 infection and assess key global surgery indicators.
- Conditions
- Surgery, Covid19, Post-Op Complication
- Trial name
- NCT04509986
- Volunteers
- 1,000 people
- Sponsor
- University of Birmingham
Postoperative Complications
Crystalloids vs Albumin Prime Solution and Postoperative Pulmonary Complications
In 2019, the investigators initiated a new priming fluid therapy strategy in the cardiopulmonary bypass (CPB) machine for patients undergoing pulmonary endarterectomy surgery.
- Trial name
- ALBUTEP (NCT04839432)
- Testing
- implementation of albumin solution in the priming of the cardiopulmonary bypass machine
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Erasme University Hospital