Clinical trials: Post Operative Pulmonary Complications
Pulmonary Congestion, Congenital Heart Disease
Utility of Lung Ultrasound in the Estimation of Extravascular Lung Water in Pediatric Population
Increased extravascular lung water (EVLW) may increase mortality and morbidity in cardiopulmonary pathology. Many factors can cause increased extravascular lung water and pulmonary edema after cardiac surgery.
- Conditions
- Pulmonary Congestion, Congenital Heart Disease, Post-Op Complication
- Trial name
- NCT04417790
- Testing
- Lung ultrasound and EVLW measurement by transpulmonary thermodilution.
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
COVID-19, Surgical Outcomes
Impact of COVID-19 on Surgical Outcomes
Following the introduction of the COVID-19 vaccination, elective surgeries have resumed, allowing for greater insight into the postoperative period and outcomes aims on-going COVID-19 infections.
- Conditions
- COVID-19, Surgical Outcomes, Postoperative Complications
- Trial name
- NCT06197282
- Testing
- Major surgery involving general anesthesia
- Where
- United States
- Volunteers
- 7,696 people
- Sponsor
- Kern Medical Center
Spinal Fusion, Transfusion
Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications
Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients.
- Conditions
- Spinal Fusion, Transfusion, Pulmonary Complication
- Trial name
- NCT05661838
- Testing
- transfusion
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Primary Graft Dysfunction, Lung Transplantation
Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation
Primary graft dysfunction (PGD) is a severe lung injury that can occur in the days following lung transplant surgery. The purpose of this study is to identify genetic factors that may put someone at risk for developing PGD.
- Trial name
- NCT00457847
- Where
- United States
- Volunteers
- 1,150 people
- Sponsor
- University of Pennsylvania
Postoperative Complications
Crystalloids vs Albumin Prime Solution and Postoperative Pulmonary Complications
In 2019, the investigators initiated a new priming fluid therapy strategy in the cardiopulmonary bypass (CPB) machine for patients undergoing pulmonary endarterectomy surgery.
- Trial name
- ALBUTEP (NCT04839432)
- Testing
- implementation of albumin solution in the priming of the cardiopulmonary bypass machine
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Erasme University Hospital
URTI, Postoperative Complications
Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic
The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional…
- Conditions
- URTI, Postoperative Complications, COVID - 19, Elective Non-cardiac Surgery
- Trial name
- URTI (NCT07157111)
- Where
- China
- Volunteers
- 2,392 people
- Sponsor
- aijun xu
Pain, Postoperative
Exploring the Effects of Transcutaneous Electrical Acupoint Stimulation Therapy on Patients After Video-Assisted Thoracoscopic Surgery
Thoracic surgery is known to be one of the most painful types of surgery. If acute postoperative pain is not properly managed, there is a high risk that it may develop into clinically significant chronic pain within six months…
- Trial name
- NCT07287657
- Testing
- Standard Analgesia, Transcutaneous Electrical Nerve Stimulation (TENS), Transcutaneous Electrical Acupoint Stimulation (TEAS)
- Where
- Taiwan
- Volunteers
- 96 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Surgery, Covid19
GlobalSurg-CovidSurg Week
Observational study to determine the optimal timing for surgery following SARS-CoV-2 infection and assess key global surgery indicators.
- Conditions
- Surgery, Covid19, Post-Op Complication
- Trial name
- NCT04509986
- Volunteers
- 1,000 people
- Sponsor
- University of Birmingham
Postoperative Complications, COVID-19
Perioperative Complications Linked to COVID-19 History in Elective Cardiac Surgery Patients
A. Primary objective Identifying risk factors for peri-operative complications in patients who have had COVID-19. B. Secondary objectives Identifying peri-operative complications in patients who have had COVID-19.
- Trial name
- NCT05752162
- Where
- 2 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Incisional Hernia, Recurrent Hernia
Pulmonary Ventilation Function Between Patients With Primary and Recurrent Incisional Hernia: a Cross-sectional Study
Purpose Chronic obstructive pulmonary disease (COPD) is a risk factor for incisional hernia, COPD has persistent airflow restriction and pulmonary ventilation dysfunction.
- Conditions
- Incisional Hernia, Recurrent Hernia, COPD, Pulmonary Ventilation Function
- Trial name
- NCT05991024
- Testing
- the incisional hernia recurrent
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Fudan University
Anesthesia, Surgery
The Effects of Individualized Lung-protective Ventilation With Lung Dynamic Compliance-guided Positive End-expiratory Pressure(PEEP) Titration on Postoperative Pulmonary Complications of Pediatric Video-assisted Thoracoscopic Surgery
This study evaluates the influence of individualized lung-protective ventilation strategy(LPVS) on postoperative pulmonary complications(PPCs) through a randomized controlled trial when children undergoing thoracoscopic surgery…
- Trial name
- PEEP (NCT05386901)
- Testing
- Conventional positive end-expiratory pressure(PEEP), Lung dynamic compliance guided positive end-expiratory pressure(PEEP)
- Where
- China
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Jiaxiang Chen
Chronic Post-operative Pain
Reducing Chronic Pain After Lung Surgery: A Trial of Limiting NSAIDs During Recovery
Chronic postoperative pain (CPOP) after video-assisted thoracic surgery (VATS) is severe because it results from lesions at multiple levels: incisions, pulmonary or nerve contusions.
- Trial name
- EVADRAINS (NCT07108582)
- Testing
- no NSAID, protocol for administering NSAIDs already used in routine care
- Volunteers
- 270 people
- Sponsor
- University Hospital, Strasbourg, France
Pneumonia, Bloodstream Infection
Clinical Outcomes in Patients With Infection by Resistant Microorganism
The goal of this individual patient data meta-analysis is to estimate the attributed and the associated health burden related to bloodstream infections, pneumonia, skin and soft tissue infections, surgical site infections and…
- Conditions
- Pneumonia, Bloodstream Infection, Urinary Tract Infections, Skin Infection
- Trial name
- NCT05880069
- Testing
- Pathogen resistant phenotype
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Universitario Virgen Macarena
Primary Graft Dysfunction, Lung Transplantation
Risk Factors That Increase the Chance of Developing Primary Graft Dysfunction After Lung Transplantation
Primary graft dysfunction (PGD) is a severe lung complication that can occur in the days after lung transplant surgery. This study will analyze blood samples to determine if high levels of certain chemicals may increase the risk…
- Trial name
- NCT00552357
- Where
- United States
- Volunteers
- 1,150 people
- Sponsor
- University of Pennsylvania
Lung Transplantation, Primary Graft Dysfunction
The Use of Surfactant in Lung Transplantation: A Randomized Control Pilot Study
1. Working Hypothesis: The purpose of the trial is to study the effect of exogenous calf surfactant (calfactant) on the prevention of primary graft failure due to ischemic-reperfusion lung injury in lung transplant patients. 2.
- Trial name
- NCT00506532
- Testing
- Surfactant (calfactant)
- Where
- Israel
- Volunteers
- 42 people
- Sponsor
- Rabin Medical Center
COVID-19, Myocardial Reperfusion Injury
Myocardial Injury and Major Adverse Outcomes in Patients With COVID-19
The study will analyze the incidence, clinical outcomes and predictors of myocardial injury in a large patient population with COVID-19 treated in Mount Sinai Hospital (MSH) system.
- Conditions
- COVID-19, Myocardial Reperfusion Injury, Cardiovascular Diseases
- Trial name
- NCT04397939
- Where
- United States
- Volunteers
- 4,695 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Surgery, Complications, Postoperative
Effects of Prone Position After Major Abdominal Surgery
Evaluation of postoperative prone position after major abdominal surgery. A randomized clinical trial of 100+100 patients and further add a voice/speech/singing protocol.
- Conditions
- Surgery, Complications, Postoperative, Lung Infection
- Trial name
- EPOS (NCT05630443)
- Testing
- prone position
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Postoperative Atelectasis
GO2 PEEP Study: Bidirectional Oxygenation Valve in Postoperative Atelectasis
This study compares a novel breathing device, called the GO2 Mouthpiece, to the standard breathing tool called the incentive spirometer, thus improving respiratory dynamics of the postoperative patient.
- Trial name
- NCT04253834
- Testing
- Incentive spirometer, GO2 Mouthpiece
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Atelectasis, Postoperative Complications
Ultrasound-guided Lung Recruitment Maneuvers for Postoperative Pediatric Atelectasis
In anesthetized children, the incidence of lung collapse with episodes of hypoxemia is high. Diaphragmatic dysfunction induced by general anesthesia is one of the most important factors in the genesis of regional losses of lung…
- Conditions
- Atelectasis, Postoperative Complications, Recruitment, Pediatric
- Trial name
- NCT05777018
- Testing
- conventional recruitment maneuvers, ultrasound-guided recruitment maneuvers
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Chronic Postoperative Pain
Data Collection for Prediction of Postoperative Chronic Pain for a Software
Postoperative Persistent Pain (PPP) is reported with a high incidence in adults 11.5-47%. This high incidence effects quality of life of patients causes social-economical problems and arises medico-legal issues.
- Trial name
- NCT02190682
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 733 people
- Sponsor
- Istanbul University