Clinical trials: Post Operative Pulmonary Complications
Anesthesia, Preoxygenation
Preoxygenation Before General Anesthesia
Rationale of the study: we aim to clarify the question (related to still unclear and not univocal response) about the protective or unnecessary role of preoxygenation in non-critically ill patients (otherwise with no high risk of…
- Trial name
- PREOX2018 (NCT03802643)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Parma
Postoperative Complications
Preventive Effects of Penehyclidine Hydrochloride Inhalation on Postoperative Pulmonary Complications
Postoperative pulmonary complications (PPCs) are major causes of postoperative morbidity, mortality, and prolonged hospital stay.The incidence of PPCs may be as high as 41% to 75% in high-risk patients.
- Trial name
- NCT02644876
- Testing
- Penehyclidine inhalation
- Where
- China
- Volunteers
- 864 people
- Sponsor
- Peking University First Hospital
Postoperative Pulmonary Complications
Effect of Continuous Intra-airway Monitoring Under Visible Double-lumen Bronchial Catheter on Postoperative Complications of Lung Surgery
The incidence of postoperative pulmonary complications (PPCs) after thoracic surgery is as high as 30-50% [1-6], which is the main cause of postoperative morbidity, death and prolonged hospital stay.
- Trial name
- NCT05830474
- Testing
- Continuous intra-airway monitoring and intervention during surgey
- Volunteers
- 376 people
- Sponsor
- Fujian Medical University Union Hospital
Postoperative Pulmonary Complications (PPCs), Cardiac Surgery in Adult Patient
Sigh Ventilation in Cardiac Surgery
The purpose of this trial is to investigate whether sigh ventilation strategy, combining sigh breaths, low tidal volume, and moderate PEEP levels, protects against major pulmonary complications within the first 7 postoperative…
- Trial name
- NCT07024420
- Testing
- Sigh Breaths, Low Tidal Volume, Moderate PEEP
- Where
- China
- Volunteers
- 686 people
- Sponsor
- Zhongda Hospital
Covid19
Post-COVID 19 Patients Undergoing Surgery
More and more patients are undergoing elective surgery after SARS-CoV-2 infection, and little is known about the residual pulmonary changes in these patients after infection and postoperative pulmonary complications.
- Trial name
- NCT04922931
- Testing
- scheduled surgery
- Where
- Spain
- Volunteers
- 207 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Postoperative Pulmonary Complications
Mechanical Power and Driving Pressure Exposure in Laparoscopic Surgery
Postoperative pulmonary complications (PPCs) remain an important cause of morbidity after abdominal surgery. Intraoperative mechanical ventilation may contribute to lung injury through the mechanical load applied to the…
- Trial name
- NCT07431242
- Testing
- Intraoperative Ventilatory Load Exposure (Mechanical Power and Driving Pressure)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istinye University
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
Lung Diseases, Lung Inflammation
Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery
The purpose of this study is to analyze the impact of the intravenous (IV) or paravertebral (PV) lidocaine administration during the intraoperative period of lung resection surgery on the appearance of postoperative…
- Conditions
- Lung Diseases, Lung Inflammation, Lung Injury, Acute, Postoperative Complications
- Trial name
- NCT03905837
- Testing
- Lidocaine, Remifentanil
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Francisco Andres de la Gala
Hyperoxia
Hyperoxia and Pulmonary Complications After Cardiac Surgery
The main objective is to demonstrate that hyperoxia in cardiac surgery increase the occurrence of post-operative pulmonary complications
- Trial name
- HYPER-CARDIO (NCT04278066)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Post-Op Infection, Adherence, Patient
The Digital Incentive Spirometer (DIS): Improving Adherence to Incentive Spirometry
The purpose of the protocol is to assess how incentive spirometer data gathered via a smartphone platform can be utilized to improve participant adherence to prescribed incentive spirometer exercises in the post-operative period.
- Conditions
- Post-Op Infection, Adherence, Patient, Pulmonary Atelectasis, Incentive Spirometry
- Trial name
- DIS (NCT03686631)
- Testing
- Smartphone Arm
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Beth Israel Deaconess Medical Center
Lung Cancer, Surgery
Intraoperative Blood Pressure Management and Dexamethasone in Lung Cancer Surgery
Surgery is the front-line therapy for non-small cell lung cancer (NSCLC) but postoperative complications remains high and patients' long-term outcome is still challenging.
- Conditions
- Lung Cancer, Surgery, Blood Pressure Management, Dexamethasone
- Trial name
- NCT04209218
- Testing
- Dexamethasone, Targeted blood pressure management, Routine blood presure management
- Where
- China
- Volunteers
- 1,988 people
- Sponsor
- Peking University First Hospital
Pulmonary Congestion, Congenital Heart Disease
Utility of Lung Ultrasound in the Estimation of Extravascular Lung Water in Pediatric Population
Increased extravascular lung water (EVLW) may increase mortality and morbidity in cardiopulmonary pathology. Many factors can cause increased extravascular lung water and pulmonary edema after cardiac surgery.
- Conditions
- Pulmonary Congestion, Congenital Heart Disease, Post-Op Complication
- Trial name
- NCT04417790
- Testing
- Lung ultrasound and EVLW measurement by transpulmonary thermodilution.
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Arrhythmia, Acute Kidney Injuries
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
This retrospective observational study aims to identify risk factors for postoperative complications in children undergoing cardiac surgery at a tertiary hospital in Brazil.
- Conditions
- Arrhythmia, Acute Kidney Injuries, Sepsis, Pneumopathy
- Trial name
- PEDS-CARE (NCT06985082)
- Testing
- THERE IS NOT A INTERVENTION
- Volunteers
- 310 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Postoperative Complications After Lung Transplantation
The Effect of Perioperative Factors on Postoperative Outcomes After Lung Transplantation
1. Evaluate the influence of perioperative factors on postoperative outcomes in patients undergoing lung transplantation patients. 2.
- Trial name
- NCT06603350
- Testing
- No intenvention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
PostoperativePulmonaryComplications
A Multicenter Randomized Controlled Clinical Trial of the Impact of Minimally Invasive Abdominal Surgery Esophageal Pressure Monitoring Guided Individualized PEEP on Postoperative Pulmonary Complications in Obese Patients
The aim of this study is to compare the effect of individualized PEEP based on transmural lung pressure and fixed PEEP on postoperative pulmonary complications during laparoscopic or robotic abdominal surgery in obese patients.
- Trial name
- NCT06996288
- Testing
- Transpulmonary pressure-guided individualized PEEP
- Volunteers
- 180 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Atelectasis, Pulmonary Infection
Bi-PAP vs Sham Bi-PAP on Pulmonary Function in Morbidly Obese Patients After Bariatric Surgery
The effect of biphasic positive airway pressure (Bi-PAP) at individualized pressures on the postoperative pulmonary recovery of morbidly obese patients (MOP) undergoing open bariatric surgery (OBS) and possible placebo…
- Conditions
- Atelectasis, Pulmonary Infection, Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Disease
- Trial name
- NCT03438383
- Testing
- Bi-PAP
- Volunteers
- 48 people
- Sponsor
- Evangelismos Hospital
Pre-Diabetes, Major Lung or Abdominal Surgery
Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism
Major surgery results in a stress- induced catabolic response, marked by post-operative insulin resistance, hyperglycemia and loss of body protein, which is associated with increased morbidity, mortality and adverse outcomes.
- Conditions
- Pre-Diabetes, Major Lung or Abdominal Surgery, Insulin Resistance
- Trial name
- NCT02393573
- Testing
- Metformin
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Postoperative Complications, Long-term Outcome
Prophylactic Penehyclidine Hydrochloride Inhalation and 3-year Outcome After Surgery
Postoperative pulmonary complications (PPCs) are major causes of postoperative morbidity, mortality, and prolonged hospital stay.The incidence of PPCs may be as high as 41% to 75% in high-risk patients.
- Trial name
- NCT03868709
- Testing
- Penehyclidine inhalation
- Where
- China
- Volunteers
- 864 people
- Sponsor
- Peking University First Hospital
Postoperative Pain
Transversus Abdominis Plane Block Versus Wound Infiltration for Pulmonary Function Preservation Following Laparoscopic Living Donor Nephrectomy
This study compares two pain control techniques in patients undergoing laparoscopic kidney donation surgery: transversus abdominis plane (TAP) block versus wound infiltration with local anesthetic.
- Trial name
- TAPWIN (NCT06837909)
- Testing
- Transversus abdominis plane (TAP) block, Wound infiltration
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
Pulmonary Atelectasis, Morbid Obesity
Use of Airway Pressure Release Ventilation in Morbidly Obese Patients Undergoing Open Heart Surgery
The goal of this Randomized Clinical trial is to to investigate if the use of Air Pressure Release Ventilation in morbidly obese patients undergoing open heart surgery will improve post operative pulmonary outcomes 60 Patients…
- Conditions
- Pulmonary Atelectasis, Morbid Obesity, Pulmonary Complication
- Trial name
- NCT05670483
- Testing
- Use Of APRV mode of Ventilation, Use of conventional Synchronized Intermittent Mandatory Ventilation (SIMV) volume control mode
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University