Clinical trials: Post-Operative Condition
Staphylococcal Aureus Infection, Surgical Site Infection (SSI)
Gene Expression Analysis of Biofilm Formation and Antimicrobial Resistance in Clinical Methicillin-Resistant Staphylococcus Aureus
Staphylococcus aureus are Gram-positive cocci that asymptomatically colonize the skin and mucosal surfaces of approximately 20-30% of healthy individuals . Although they commonly exist as a harmless commensal organisms, S.
- Trial name
- NCT07796555
- Testing
- swab from lesion, Biochemical reactions, Antibiotic sensitivity
- Volunteers
- 100 people
- Sponsor
- Sohag University
Postoperative Pain, Opioid Use
Sex Hormones, Postoperative Pain and Opioid Use
Aim 1- To identify relationships between sex hormone levels and postoperative pain and opioid use. Aim 2: To determine whether the effects of testosterone on postoperative pain and opioid use are mediated by immune factors
- Trial name
- SPO (NCT06023225)
- Testing
- Pain, Opioid use
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Washington University School of Medicine
Operation Wound; Infection, Bacterial Infections
Nudging Effect of Timer on Surgical Rub
To study whether a device has a nudging effect on the time spend on surgical rub.
- Conditions
- Operation Wound; Infection, Bacterial Infections, Surgical Procedure, Unspecified
- Trial name
- NCT04609384
- Testing
- Alcohol rub timer device
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Sygehus Lillebaelt
Kidney Cancer
Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery.
- Trial name
- NCT00047138
- Testing
- dactinomycin, carboplatin, cyclophosphamide
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 350 people
- Sponsor
- University of Leicester
Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients
The goal of this randomized clinical trial is to compare the immediate use of steroids after surgery for accelerated discharge in adolescent idiopathic scoliosis and neuromuscular scoliosis after a posterior spinal fusion.
- Trial name
- NCT06023043
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's Hospital Los Angeles
Open-angle Glaucoma (OAG)
5-Year Postoperative Outcomes of Patients Who Completed the CREST Study
This study is designed to collect clinical data at 3, 4, and 5 years postoperatively for participants who completed the CREST Study without having secondary IOP-lowering surgery in the study eye(s).
- Trial name
- CREST-XT (NCT07480343)
- Testing
- CycloPen Micro-Interventional Cyclodialysis System, CycloPen Micro-Interventional Cyclodialysis System Post Cataract
- Where
- 10 sites in United States
- Volunteers
- 250 people
- Sponsor
- Iantrek, Inc.
Prosthesis-Related Infections, Hip Prosthesis Infection
Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy.
It is not known in the literature how much sonication affects the patient's treatment. Another important issue is that the place of this method in diagnosis is not clear.
- Conditions
- Prosthesis-Related Infections, Hip Prosthesis Infection, Joint Infection, Biofilm
- Trial name
- NCT04304885
- Testing
- Sonication method
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Surgery, Surgical Site Infection
Intraoperative Hygiene Measures and Surgical Site Infections
Surgical site infections are associated with high morbidity and cost Hypothesis: Extended intraoperative hygiene measures decrease surgical site infections in general surgery compared to standard hygiene measures.
- Conditions
- Surgery, Surgical Site Infection, Hygiene, Discipline
- Trial name
- NCT00555815
- Where
- Switzerland
- Volunteers
- 1,032 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Preoperative Fasting, Perioperative Patient Comfort / Quality of Care
Quality Improvement Project to Reduce Preoperative Fasting Times Before Elective Procedures
This single-center quality improvement project evaluates preoperative fasting times before elective procedures requiring anesthesiology care.
- Conditions
- Preoperative Fasting, Perioperative Patient Comfort / Quality of Care, Postoperative Nausea and Vomiting (PONV), Postoperative Pulmonary Complications
- Trial name
- NCT07488468
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- University of Giessen
Facial Injuries, Pain
Topical Dexamethasone/Diclofenac Hydrogel for Postoperative Pain and Swelling in Facial Soft Tissue Injuries
This randomized, controlled clinical trial will evaluate the clinical effects of a topical thermoresponsive hydrogel containing dexamethasone sodium phosphate and diclofenac sodium on postoperative pain and facial swelling in…
- Conditions
- Facial Injuries, Pain, Swelling
- Trial name
- NCT07853664
- Testing
- Poloxmer F-127 Hydrogel with Dexamethasone/Diclofenac
- Where
- Yemen
- Volunteers
- 52 people
- Sponsor
- Thamar University
Pain, Postoperative
Evaluation of Postoperative Pain With Eddy Tips (EPPET)
This investigation will focus on the use of EDDY tips, because it is known that the complete debridement of the canal is very difficult, which leads to an accumulation of tissue debris, bacteria and their products, resulting in…
- Trial name
- NCT03946306
- Testing
- 5,25% NaOCl with syringe needle irrigation alone, EDDY
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- Universidade do Porto
Respiratory Depression
Observation of Respiration Following Regional Anaesthesia With Intrathecal Opioids for Caesarean Section
Spinal Administration of opioids offers segmental analgesia, but has side effects including pruritus, nausea and vomiting, urinary retention, hypotension, and respiratory depression, both early and delayed.
- Trial name
- NCT00544947
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- NHS Greater Clyde and Glasgow
Esophageal Squamous Cell Carcinoma
Individualized Tumor-Informed CtDNA Analysis for Monitoring Postoperative Recurrence in ESCC (NEOCRTEC2401)
The goal of this observational study or is to explore the correlation between dynamic changes in postoperative circulating tumor DNA (ctDNA) and recurrence risk using a novel, tumor-informed ctDNA detection technique, thus laying…
- Trial name
- NCT06561178
- Testing
- molecular residual disease detection
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-Sen University Cancer Center
Obesity, Adolescent Obesity
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
The study plans to learn more about what happens to the body after bariatric surgery in people 12 to 24 years old. The study aims to understand why people respond differently to bariatric surgery and how to define success beyond…
- Conditions
- Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory
- Trial name
- PRESSURE (NCT06575738)
- Testing
- Injectable semaglutide or injectable tirzepatide, Standard postoperative care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Postoperative Pain
Prospective Randomized Comparison of Clinical Results of Hand Assisted Laparoscopic Splenectomies and Open Splenectomies
ABSTRACT Background: Although there are some comparative studies between laparoscopy and hand-assisted laparoscopic splenectomy (HALS) in splenomegaly cases, there is no study of the differences between HALS and open splenectomy…
- Trial name
- NCT00754806
- Volunteers
- 27 people
- Sponsor
- Istanbul University
Postoperative Cognitive Dysfunction, Postoperative Delirium
Perioperative GDNF as a Predictive Factor for Postoperative Delirium and Adverse Neurological Outcomes in Pediatric Surgery
To observe the dynamic changes in serum levels of inflammatory cytokines (e.g., IL-6, TNF-α), Brain-Derived Neurotrophic Factor (BDNF), and Glial Cell Line-Derived Neurotrophic Factor (GDNF) during the perioperative period in…
- Trial name
- NCT07192549
- Testing
- Sevoflurane group, Propofol group
- Volunteers
- 200 people
- Sponsor
- General Hospital of Ningxia Medical University
Spontaneous Pneumothorax, Recurrence
Most Preventable Surgical Option to Reduce Primary Spontaneous Pneumothorax Patients' Postoperative Recurrence: A Prospective Cohort Study
To investigate the most preventable option to reduce primary spontaneous postoperative recurrence.
- Conditions
- Spontaneous Pneumothorax, Recurrence, Surgery
- Trial name
- NCT04758143
- Where
- Japan
- Volunteers
- 450 people
- Sponsor
- Yuka Kadomatsu
Abdominal Wall Wound, Ventral Hernia
Mass Closure vs Layer by Layer Closure
to assess two different ways of closure of laparotomy in children and infants
- Conditions
- Abdominal Wall Wound, Ventral Hernia, Incisional Hernia
- Trial name
- NCT06016426
- Testing
- Mass closure vs layer by layer closure of transverse laparotomy incisions in children and infants.
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Pain
Efficacy of Intravenous Dexamethasone on Postoperative Caudal Analgesia in Pediatric Orchiopexy
The purpose of this study is to evaluate postoperative pain control for pediatric patients.
- Trial name
- NCT01041378
- Testing
- dexamethasone
- Volunteers
- 80 people
- Sponsor
- Yonsei University
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