Clinical trials: Post-Operative Condition
Postoperative Pain
Study to Investigate TIVA With Propofol on Postoperative Pain and Side Effects
Propofol is a commonly used anaesthetic with rapid recovery and less side effects and total intravenous anaesthesia (TIVA) with propofol is a common technique now.
- Trial name
- NCT03058354
- Testing
- Propofol, general anaesthesia
- Where
- Hong Kong
- Sponsor
- The University of Hong Kong
Postoperative Analgesia, S-ketamine
Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias
Caudal analgesia with ropivacaine is commonly used in sub-umbilical pediatric surgery. However, increasing the dosage of ropivacaine has not been found to prolong the action significantly while complications will be serious.
- Conditions
- Postoperative Analgesia, S-ketamine, Pediatrics, Caudal Block
- Trial name
- NCT05922605
- Testing
- S-ketamine & Ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Tao Zhang
Emergence Agitation
Propofol in Emergence Agitation
The purpose of the study is to see if a small dose of propofol given intravenously (through a needle into a vein) at the end of anesthesia can make it less likely that children will be agitated as the come out of the anesthetic.
- Trial name
- NCT00535613
- Testing
- Propofol
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Wisconsin, Madison
Snoring, Strep Throat
Comparing Healthcare Utilization Between Adenotonsillectomy Patients With and Without Postoperative Antibiotic Use
This study is designed to look at healthcare utilization following the removal of tonsils and adenoids in pediatric patients who are not given an antibiotic following surgery.
- Trial name
- NCT01561703
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Missouri-Columbia
Enhanced Recovery After Surgery, Appendicitis
Safety and Efficacy of ERAS Therapeutic Protocol for Complicated Appendicitis in Children
Complicated appendicitis in pediatrics is frequent, potentially serious and complex to manage. The implementation of a ERAS model would allow optimizing perioperative care, offering a shorter hospital stay, reducing complications…
- Conditions
- Enhanced Recovery After Surgery, Appendicitis, Children, Only
- Trial name
- ERAS (NCT05511194)
- Testing
- Enhanced Recovery After Surgery therapeutic protocol, Conventional management
- Volunteers
- 40 people
- Sponsor
- Instituto Mexicano del Seguro Social
Tonsillectomy, Adenoidectomy
Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy
Tonsillectomy (the surgical removal of the tonsils) is a commonly performed surgery in children. One risk of tonsillectomy is postoperative bleeding, and this can be more dangerous in children because their blood volume is lower…
- Trial name
- NCT01605903
- Testing
- Ibuprofen, Acetaminophen
- Where
- 5 sites in United States
- Volunteers
- 741 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Newborn
The Effect of White Noise and Pacifier Applications on Pain and Crying Time
The objective of the study was to determine the effect of white noise and pacifier applications on pain and crying time in newborns during painful interventions. The research was planned experimentally.
- Trial name
- NCT06535061
- Testing
- white noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sanko University
Dental Caries
Postoperative Hypersensitivity Randomized Comparative Effectiveness Research Trial
Postoperative hypersensitivity (POH) is a problem for many patients as determined by the recent Practitioners Engaged in Applied Research and Learning (PEARL) study of POH following occlusal caries restoration.
- Trial name
- POH RCERT (NCT01268605)
- Testing
- Restoration with a dentin bonding agent (DBA), Restoration with a resin modified glass ionomer liner (RMGI)
- Where
- 41 sites in United States
- Volunteers
- 341 people
- Sponsor
- Pearl Network
Endometriosis
Postoperative Cyclic Oral Contraceptive Use for the Prevention of Endometrioma Recurrence
Ovarian endometriotic cyst (endometrioma) is one of the most common endometriotic lesions, and conservative laparoscopic surgery is the treatment of choice. However, the recurrence after surgery is common.
- Trial name
- NCT01092494
- Where
- South Korea
- Volunteers
- 232 people
- Sponsor
- Samsung Medical Center
Rectal Cancer
Anastomotic Leakage After Anterior Resection of Rectal Cancer
Anastomotic leakage (AL) is one of the most-feared postoperative complications after anterior resection of rectal cancer. This complication compromises both short term and long term outcome of patients.
- Trial name
- NCT03281070
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Friendship Hospital
Short Bowel Syndrome
Effect of a Short Message Service Intervention on Patients With Short Bowel Syndrome
The investigators will be using a text messaging intervention to identify potentially dangerous and re- admission causing symptoms in patients with Short Bowel Syndrome (SBS) on Total Parenteral Nutrition (TPN).
- Trial name
- NCT03419156
- Testing
- Text Message Arm Intervention
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- St. Louis University
Pain, Postoperative
Safety and Clinical Utility Study of SSEC Fentanyl 40 mcg for Acute Post-op Pain Management in Pediatric Participants
The objective of this study is to evaluate the safety and clinical utility of the active, SSEC fentanyl 40 micrograms (mcg) for the management of acute, postoperative pain in pediatric participants.
- Trial name
- NCT02395653
- Testing
- fentanyl
- Where
- 10 sites in United States
- Volunteers
- 71 people
- Sponsor
- The Medicines Company
Severe Hyperglycemia, Postoperative Infection
Intraoperative Hyperglycemia and Infections After Orthopedic Surgery
Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy.
- Conditions
- Severe Hyperglycemia, Postoperative Infection, Orthopedic Patients
- Trial name
- NCT03903354
- Testing
- Incidence of infections within 7 days postoperatively
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Federico Bilotta
Post Operative Pain
Nalbuphine Plus Caudal Bupivacaine in Hypospadius Repair
Caudal aneasthesia for pediatric surgery was first reported in 1933. Since then, studies have described the indications for pediatric caudal block, the level of analgesia, doses, advantages and disadvantages of this technique.
- Trial name
- NCT03476772
- Testing
- Nalbuphine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Single-ventricle, Heart Diseases
Colchicine in Postoperative Fontan Patients
The investigators found that there is inflammation in the chest drainage in patients after the Fontan operation. The investigators want to test the theory that Colchicine, an anti- inflammatory medication, can decrease the…
- Trial name
- CPFP (NCT03575572)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Pain, Postoperative, Carpal Tunnel Syndrome
The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release
Carpal Tunnel Syndrome patients undergoing carpal tunnel release surgery performed by the PI will receive intra-operative injections of bupivacaine (Marcaine).
- Trial name
- CTR (NCT03729375)
- Testing
- 10cc injection of bupivacaine, 20cc injection of bupivacaine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of South Florida
Surgical Site Infection, Sternal Wound Infection
Sternal Wound and Aortic Graft (SWAG), an Observational Cohort Study.
The aim of this study is to systematically explore the perioperative presence of P acnes in all layers of sternal wound incision as well as contamination of graft material and prosthetic valves during primary operation.
- Trial name
- SWAG (NCT04592328)
- Testing
- Bacterial cultures taken during surgery.
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Örebro County
Liver Disease
Preventive and Reversional Effect of Vitamin D on Parenteral Nutrition Associated Liver Disease
Patients who accept long-term parenteral nutrition tend to suffer from liver injury. The mechanism for this injury has two possible explanations. The first possible reason is intrinsic toxic effects of parenteral nutrition.
- Trial name
- NCT02452177
- Testing
- Vitamin D
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shengxian Fan
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Pain, Referred
Subcutaneous Bupivacaine Decrease Post-op Pain in Patients Undergoing C-Section
The purpose of this study is to determine if giving an injection of numbing medication at the incision at the end of cesarean will help control pain AFTER cesarean delivery.
- Trial name
- NCT03383588
- Testing
- Bupivacaine, Morphine, Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
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