Clinical trials: Post-Operative Condition
Delirium on Emergence
Effect of Duration of Exposure of Anesthesia With Sevoflurane on Emergence Delirium
Emergence delirium which is a phenomenon seen commonly in preschool kids anesthetized with Sevoflurane. Restless recovery from anesthesia may not only cause injury to the child or to the surgical site, but may also lead to the…
- Trial name
- NCT02509221
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- State University of New York - Upstate Medical University
Hirschsprung's Disease
Effects of Butyrate Enemas on Postoperative Intestinal Motility Disorders in Hirschsprung's Disease
Hirschsprung's disease (HD) is a rare congenital disorder (1/5000) defined by the absence of ganglion cells in the submucosal and myenteric plexuses along a variable length of the digestive tract.
- Trial name
- Buty-Hirsch (NCT03660176)
- Testing
- Sodium Butyrate, routine management
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Postoperative Pain
Quadratus Lumborum Block Versus Transversus Abdominis Block
The advent of laparotomy replacement by minimally invasive techniques brought the obvious benefit of postoperative pain reduction.
- Trial name
- NCT04367233
- Testing
- General anesthesia, Transverse abdominal block, Quadratus lumborum block
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Infection
Clinical Post-operative Assessment of Chronic Signs & Symptoms Related to Infected Primary Molars After Using Rotary Versus Manual Systems in Cleaning the Root Canals
One of the most important concerns in pediatric dentistry is the loss of necrotic primary molars leading to space loss. pulpectomies for primary teeth with severe pulpal involvement should be considered as the treatment of…
- Trial name
- NCT03684915
- Testing
- Rotary files
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Congenital Complete Atrioventricular Heart Block, High Grade Atrioventricular Block
Effects of Chronic Right Ventricular Pacing in Children With Advanced Atrioventricular Block
Recent studies have shown that chronic stimulation of the right ventricle can cause deleterious effects to cardiac function and synchronicity.
- Conditions
- Congenital Complete Atrioventricular Heart Block, High Grade Atrioventricular Block, Postoperative Complete Heart Block
- Trial name
- NCT01477658
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- University of Sao Paulo
Postoperative Pain
The Pharmacokinetics of Ketorolac Tromethamine Administered Intranasally (IN) for Postoperative Pain in Children Aged 12 Through 17 Years
This was an open-label PK study in pediatric subjects who had undergone general surgery. Each subject's study participation consisted of a screening visit, a single-dose treatment with intranasal ketorolac (IN) tromethamine, and…
- Trial name
- NCT01363076
- Testing
- Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Egalet Ltd
Post Operative Pain, Appendicitis
Evaluation of Local Anesthetic at Incision Site
Patient will have usual appendectomy surgery with an injection of local or saline at incision site either before or after the incision at random.
- Trial name
- NCT02483689
- Testing
- Pre Incisional Local Anesthetic, Pre-Incisional Saline, Post-Closure Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Valley Anesthesiology Consultants
Postoperative Pain
Dexmedetomidine Versus Fentanyl for Sedation of Postoperative Mechanically Ventilated Neonates
Newborn infants experience pain after surgical procedures,prevention and management of pain in neonates is important due to its deleterious consequences.
- Trial name
- NCT05324891
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Low Anterior Resection Syndrome, Radiotherapy
Development and Validation of The Post-RT LARS Prediction Model (PORTLARS)
Bowel dysfunction is common after a restorative rectal cancer resection. Neoadjuvant radiotherapy is an influential factor that impairs bowel function and quality of life.
- Conditions
- Low Anterior Resection Syndrome, Radiotherapy, Rectal Cancer
- Trial name
- PORTLARS (NCT05129215)
- Testing
- Questionnaire
- Where
- China
- Volunteers
- 901 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Colonic Cancer, Postoperative Care
Rehabilitation Following Laparoscopic Colonic Surgery
The standard procedure for treating colonic cancer is changing from open surgery to laparoscopic surgery. Following open colonic surgery patients are fatigued and loss body mass and have a reduction in physical function, but the…
- Conditions
- Colonic Cancer, Postoperative Care, Fatigue
- Trial name
- NCT00938210
- Testing
- Laparoscopic colonic surgery
- Where
- 2 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- Aarhus University Hospital
URTI, Bronchiolitis
Assessement of Effectiveness of Seawater Nasal Sprays on Sinonasal Symptoms
The purpose of this post-market clinical investigation is to assess in a real-life setting, the effectiveness, usage, tolerance, safety and satisfaction of 4 isotonic and hypertonic seawater-based CE-marked nasal sprays.
- Conditions
- URTI, Bronchiolitis, COVID - 19, Allergic Rhinitis
- Trial name
- SeaBridge (NCT07262450)
- Testing
- Respimer® Hygiene-Prevention -Baby, kids, adults, Respimer® Hygiene-Prevention Kids, adults, Respimer® Decongestion Baby, kids, adults
- Where
- 32 sites in France
- Volunteers
- 1,065 people
- Sponsor
- Laboratoire de la Mer
Cardiac Event
Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery
To evaluate plasma concentrations of Cefuroxime in this patient population To determine if certain pathophysiological and/or iatrogenic conditions alter the pharmacokinetics in this patient group.
- Trial name
- PHOXEY (NCT02850250)
- Testing
- Cefuroxime
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Agitation, Anesthesia
Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children
Emergence delirium (ED) from general anesthesia posts risk and harm to pediatric population undergo general anesthesia. The purpose of the study is to compare the use of dexmedetomidine versus placebo in reducing the incidence…
- Conditions
- Agitation, Anesthesia, Pediatrics
- Trial name
- DexPeds (NCT00857727)
- Testing
- Dexmedetomidine, Saline
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Acute Appendicitis
TAP Block for Laparoscopic Appendicectomy in Adults
Laparoscopic (key-hole) appendicectomy is a minimally invasive procedure when compared to open large bowel resection, but is still associated with a significant amount of pain and discomfort.
- Trial name
- NCT03252561
- Testing
- Ultrasound guided Transversus Abdominis Plane (TAP) bock, Local anaesthetic infiltration of laparoscopic port sites
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Pectus Excavatum
Postoperative Recovery Quality According to Preoperative Fasting Time in Pediatric Patients Undergoing Nuss Operation
Preoperative fasting is intended to lower the amount of gastric contents in order to decrease the incidence of aspiration associated with endotracheal intubation.
- Trial name
- NCT04068324
- Testing
- New Care No Nil Per Os
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Jung Min Koo
Postoperative Pain
Postoperative Pain After the Removal of Root Canal Filling Material
The aim of this study was to evaluate the intensity and duration of postoperative pain after the removal of root canal filling material in retreatment procedures of upper incisor teeth with chronic apical periodontitis, using…
- Trial name
- NCT02905773
- Testing
- root canal therapy, root canal retreatment
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pediatric, Elective
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. IV Dexmedetomidine Improves LMA Insertion Success and Decreases Coughing, While IV Lidocaine Decreases Postoperative Cough.
Laryngeal Mask Airways Are Supraglottic Devices Used to Maintain Airway Patency During Anesthesia and in Difficult Airways. LMA may help in reducing postoperative pulmonary complications.
- Conditions
- Pediatric, Elective, Surgery in Early Childhood
- Trial name
- DEX LMA (NCT07562308)
- Testing
- Dexamedomedine, Lidocaine (drug)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Pain, Postoperative
Effect of Auditory Distractions on Pediatric Postoperative Pain
The aim of the study was to determine the effect of different auditorial methods of attention distraction on postoperative pain and anxiety in children.
- Trial name
- NCT03704961
- Testing
- music and audiobook listening
- Volunteers
- 3 people
- Sponsor
- Uludag University
Atelectasis, Block
Effect Posterior QLB on Atelectasis
We aimed to investigate the effect of posterior quadratus lumborum block on postoperative atelectasis in inguinal hernia surgery in pediatric patients.
- Conditions
- Atelectasis, Block, Pediatrics, Quadratus Lumborum Block
- Trial name
- NCT04830280
- Testing
- posterior quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University