Clinical trials: Post-Operative Condition
Anesthesia, Anesthesia Emergence Delirium
A Single Blinded Randomized Controlled Trial Testing the Efficacy of a Pediatric Interactive Relational Agent vs. Standard Preoperative Education
The purpose of this study is to determine the efficacy of enhanced preoperative education using a Pediatric Interactive Relational Agent (PIRA), designed for children aged 4 through 10 years and their families, compared to the…
- Conditions
- Anesthesia, Anesthesia Emergence Delirium, Procedural Anxiety
- Trial name
- NCT04586569
- Testing
- Pediatric Interactive Relational Agent (PIRA)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Boston Children's Hospital
Liver Diseases, Liver Cirrhosis
Intraoperative Phlebotomies and Bleeding in Liver Transplantation
Liver transplantation are surgeries associated with important bleeding and often require perioperative red blood cell (RBC) transfusions.
- Conditions
- Liver Diseases, Liver Cirrhosis, Surgery, Surgery--Complications
- Trial name
- TOF_PHLEBO (NCT04826666)
- Where
- Canada
- Volunteers
- 679 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Behavior Problem
Effects of Esketamine on Postoperative Behavioral Changes in Children Undergoing Tonsillectomy and/or Adenoidectomy
The goal of this clinical trial is to learn the effect of intravenous esketamine in postoperative negative behavior changes in children compared to placebo (a look-alike substance that contains no drug).
- Trial name
- NCT06579937
- Testing
- Esketamine hydrochloride, normal saline
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Fujian Provincial Hospital
Emergence Delirium, Pediatric Dental General Anesthesia
Pre-emptive Local Anesthesia and Emergence Behavior After Pediatric Dental General Anesthesia
This study will evaluate whether pre-emptive local anesthesia improves early recovery after ambulatory pediatric dental general anesthesia.
- Conditions
- Emergence Delirium, Pediatric Dental General Anesthesia, Postoperative Recovery
- Trial name
- PEDLA-QOR (NCT07604337)
- Testing
- Pre-emptive Local Anesthesia, Articaine Hydrochloride With Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- seher orbay yasli
the Effect of TEAS on the Children' Pain and Agitation
Effects of Perioperative TEAS on Postoperative Pain and Agitation in Pediatric Adenoidectomy and Tonsillectomy
Adenoidectomy and tonsillectomy are generally performed during childhood to help reduce snoring and improve sleep or caused by recurrent infection.And insufficient analgesia may result in postoperative sore throat, difficulty…
- Trial name
- NCT05330494
- Testing
- transcutaneous electrical acupoint stimulation(TEAS)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xian Children's Hospital
Pain, Postoperative Pain
Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins
The aim of this study is to compare the effect of Neem (azadirachta indica) and 2.5% sodium hypochlorite as root canal irrigants on the intensity of post-operative pain and the amount of endotoxins in necrotic teeth.
- Conditions
- Pain, Postoperative Pain, Postoperative Complications, Necrosis
- Trial name
- NCT03312153
- Testing
- Neem, 2.5% sodium hypochlorite
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Congenital Heart Defect
Prospective Evaluation of Changes in Tissue Oxygen Saturation in Brain and Kidney in Children Admitted to Intensive Care in the Postoperative Period of Cardiac Surgery
It is estimated that the incidence of congenital heart disease varies between 0.5 and 1% of live births, 5,000 new cases per year currently in France These are serious diseases that can be life-threatening to more or less short…
- Trial name
- NCT02884973
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Cerebral Palsy, Post-operative Pain
The Post-Operative Pain in Cerebral Palsy (POPPIES) Trial
Cerebral palsy is common. It affects approximately 3 per 1000 children. Hip displacement due to muscle tightness (spasticity) occurs in up to half of the more severely affected children, and many of these children require major…
- Trial name
- POPPIES (NCT01437644)
- Testing
- botulinum toxin intramuscular injection
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Scoliosis
Effect of Intraoperative Paravertebral Block on Postoperative Pain and Recovery in Patients Undergoing Mechanical Correction for Scoliosis
Pain management after scoliosis surgery is challenging for the anesthesiologists. This surgery causes severe postoperative pain and patients undergoing these operations are children or adolescents who are increased pain sensation…
- Trial name
- NCT04773509
- Testing
- Paravertebral block
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Yonsei University
Esophageal Neoplasms, Carcinoma, Squamous Cell
A Trial of Chemotherapy Before and After Surgery for Stage II,III Esophageal Squamous Cell Carcinoma
To determine whether chemotherapy before surgery makes better outcome than chemotherapy after surgery in patients with esophageal squamous cell carcinoma
- Trial name
- NCT00190554
- Testing
- Surgery +(Cisplatin 80 mg/㎡+5FU 800mg/㎡×5days)×2, (Cisplatin 80 mg/㎡+5FU 800mg/㎡×5days)×2＋Surgery
- Where
- 24 sites in Japan
- Volunteers
- 330 people
- Sponsor
- Japan Clinical Oncology Group
Pain
Reducing Operative and Post-operative Morbidity in Living Kidney Donors With the Airseal System
The purpose of this study is to determine if the Airseal System will reduce post-operative pain and reduce the need for narcotics in laparoscopic living kidney donor surgeries.
- Trial name
- NCT02262039
- Testing
- Valveless recirculating insufflation (VTI), Conventional pressure
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Yale University
Emergence Agitation
A Comparison of Emergence Agitation by Sevoflurane for Intraoperative Sedation Associated With Caudal Block
This study was performed to compare the incidence of EA between two dose of sevoflurane for sedation with caudal block in children, and intended to find the optimal dose for prevention of sevoflurane induced emergence agitation
- Trial name
- NCT03134547
- Testing
- low dose sevoflurane group, high dose sevoflurane group
- Volunteers
- 40 people
- Sponsor
- Yeungnam University College of Medicine
Postoperative Nausea and Vomiting
Dexamethasone Versus Local Infiltration Technique for Tonsillectomy in Children
Tonsillectomy is one of the most frequent surgical operations performed in children [1-4]. It is usually associated with postoperative nausea and vomiting (PONV) with an incidence ranging from 23% to 73% [2].
- Trial name
- NCT02355678
- Testing
- dexamethasone, Local anesthetic infiltration, General anesthesia
- Where
- Lebanon
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Makassed General Hospital
Gastric Cancer (GC)
Recurrence and Prognosis Prediction Model for Gastric Cancer
This study, utilizing a large-scale multicenter Eastern database, has established a Deep Learning-based predictive model for recurrence following gastric cancer surgery, which demonstrates robust discriminatory power for early…
- Trial name
- NCT07243847
- Testing
- surgery and/or chemo
- Volunteers
- 5,000 people
- Sponsor
- Fudan University
Type 1 Diabetes Mellitis
Diathermy On Diabetes Glucose Monitoring Effectiveness
The goal of this observational study is to investigate if diathermy (a surgical tool that uses electrical energy to control bleeding) has any affect on the accuracy and functioning of continuous glucose monitoring systems in…
- Trial name
- DODGE (NCT07583238)
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- University of Nottingham
Colorectal Cancer
Effects of Reiki Applied to Patients Undergoing Colorectal Cancer Surgery on Postoperative Pain, Anxiety, Physiological Parameters and Recovery
Reiki touch therapy has been used for many years, especially on pain, anxiety and physiological parameters, and studies have been found to show that it is effective.
- Trial name
- NCT07175558
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University - Cerrahpasa
Factor 10 Deficiency
Registry Study of COAGADEX® Patients With Moderate or Severe Hereditary Factor X Deficiency Undergoing Major Surgery
This is a non-interventional, multicenter, post-marketing registry study in three patients with moderate or severe hereditary FX deficiency, to assess Coagadex administered peri-operatively for hemostatic cover in major surgery…
- Trial name
- NCT03161626
- Testing
- Coagadex
- Where
- 3 sites in United States
- Volunteers
- 3 people
- Sponsor
- Bio Products Laboratory
Depth of Anaesthesia, EEG
EEG Monitoring Under Anaesthesia in Children: Towards Personalized Anaesthesia Care
Electroencephalographic recordings (EEG) present an opportunity to monitor changes in human brain electrical activity during changing states of consciousness during general anesthesia.
- Conditions
- Depth of Anaesthesia, EEG, Anesthesia Emergence Delirium
- Trial name
- EEGPAC (NCT04103138)
- Testing
- Sedline EEG sensor placement, Sedline EEG monitoring
- Where
- Singapore
- Volunteers
- 200 people
- Sponsor
- KK Women's and Children's Hospital
Magnesium Sulphate, Dexmedetomidine
Efficacy of Intraoperative Magnesium Sulphate vs Dexmedetomidine on Emergence Agitation in Pediatric Patients
This study aimed to compare the effectiveness of intraoperative magnesium sulfate versus dexmedetomidine infusions on emergence agitation that follows anesthesia using sevoflurane immediately and after 30 min in the…
- Conditions
- Magnesium Sulphate, Dexmedetomidine, Emergence Agitation, Pediatric Patients
- Trial name
- NCT06977425
- Testing
- Magnesium sulphate, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Emergence Delirium
Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence agitation is commonly encountered after receiving inhalation anesthesia. This distressing phenomenon carries risks that are harmful to patients, caregivers and medical personnel.
- Trial name
- NCT06482125
- Testing
- Dexmedetomidine, Sevoflurane
- Where
- Indonesia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Pelita Harapan University
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