Clinical trials: Preterm
Cytomegalovirus
Cytomegalovirus (CMV) Transmission by Frozen Breast Milk in Preterms
Cytomegalovirus infection threatens preterm infant. We investigated, whether thawed breast milk is a mode of transmission
- Trial name
- NCT00668798
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Hyperbilirubinemia
Validity of Transcutaneous Bilirubin Monitoring in Preterm Infants
The most common and widely accepted method of monitoring bilirubin levels in neonates is the use of the laboratory analyzation of serum blood levels.
- Trial name
- TcB (NCT03195998)
- Testing
- TcB Measurement
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Pediatrix
BPD - Bronchopulmonary Dysplasia, Pulmonary Hypertension
Controlled Remote Monitoring and Optimization of Oxygen Therapy in Preterm Infants
The project is a national, prospective, multicenter, interventional pilot project focused on controlled remote monitoring and optimization of oxygen therapy for premature infants in the Czech Republic.
- Trial name
- NCT07161908
- Testing
- Pulse oximeter
- Where
- 4 sites in Czechia
- Volunteers
- 70 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Enteropathy, Necrotizing Enterocolitis
Use of Faecal Calprotectin to Predict Enteropathy of the Preterm Neonates
This study aims to evaluate a clinico-biological predictive score, associating the faecal calprotectin, for the diagnosis of enterocolitis and enteropathy of the preterm neonates.
- Trial name
- CALPROPREMA (NCT02010268)
- Testing
- Collection of stool samples
- Where
- France
- Volunteers
- 122 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prematurity
Preterm Donor Human Milk Supplementation of Mother's Own Milk in VLBW Infants
This prospective randomized controlled trial aims to investigate whether feeding very low birth weight (VLBW) infants with Mother's own milk (MOM) supplemented with either preterm (PDM) or term donor milk (TDM), when MOM is…
- Trial name
- NCT05675397
- Testing
- donor human milk
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Pre-Term, Respiratory Distress Syndrome, Newborn
NeO2Matic-Pilot Trial
The main goal of this trial is to test if: automated adjustment of supplemental oxygen to preterm infants in noninvasive respiratory support based on feedback from a measurement of blood-oxygen saturation results in more stable…
- Conditions
- Pre-Term, Respiratory Distress Syndrome, Newborn, Retinopathy of Prematurity, Bronchopulmonary Dysplasia
- Trial name
- NEO2MATIC (NCT05629910)
- Testing
- O2Matic
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sexual Dysfunction, Erectile Dysfunction
Management of Sexual Dysfunction With Bioresonance Technique
Bioresonance is the big promise of the medical technology of the future because it stimulates the self-regenerating system of the body by affecting the body's most essential procedures.
- Conditions
- Sexual Dysfunction, Erectile Dysfunction, Premature Ejaculation
- Trial name
- NCT02028013
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Man Clinic for Andrology, Male Infertility and Sexual Dysfunction
Pain
Metabolism and Toxicity of Acetaminophen
The purpose of this study is to investigate how acetaminophen (APAP) is released into the urine and blood; to determine how the blood levels of acetaminophen and its breakdown products affect the preterm infant's health; to…
- Trial name
- NCT01328808
- Testing
- Acetaminophen/APAP
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- John van den Anker
Perinatal Disorders of Growth and Development
Effect of Intensive Dietary Intervention in Children With Birth Weight Between 1500 and 2000 g
There are few scientific reports on preterm infants with birth weights between 1500 and 2000g. Adequate and properly balanced supply of nutrients believed to better growth and cognitive development in this patient group, and…
- Trial name
- CAKE (NCT02833818)
- Testing
- CAKE-intervention, CAKE-control
- Volunteers
- 200 people
- Sponsor
- Elin Wahl Blakstad
Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia
High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Lung Volume Monitored by Electric Tomography Impedance.
Background Ventilator induced lung injury (VILI) remains a problem in neonatology. High frequency oscillatory ventilation (HFOV) provides effective gas exchange with minimal pressure fluctuation around a continuous distending…
- Conditions
- Respiratory Distress Syndrome In Premature Infants, Bronchopulmonary Dysplasia, Ventilator-Induced Lung Injury, Functional Residual Capacity
- Trial name
- NCT01962818
- Testing
- HFOV combined with sigh breaths
- Where
- Australia
- Volunteers
- 16 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Respiratory Distress Syndrome
Caffeine Treatment in in the Delivery Room
Background. In recent years, particular attention has been paid to all interventions that could help reduce the need for mechanical ventilation MV and, therefore, the risk of BPD.
- Trial name
- CAFROOM (NCT04044976)
- Testing
- Caffeine Citrate
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Florence
Premature Birth
Brain Training in Preterm Children at Risk for Inattention, Hyperactivity, and Executive Function Impairment
The purpose of this study is to determine if different forms of child-friendly, computer-based puzzles and games ("brain training") targeting executive function (EF) skills (i.e., thinking, problem-solving) result in improvements…
- Trial name
- NCT02588391
- Testing
- Brain Training (Active), Brain Training (Passive), Brain Training (Active or Passive)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Stanford University
Preterm Infant
Acoustics as a Metric of Airway Pressure in Premature Infants Using Bubble Continuous Positive Airway Pressure
This is an observational, proof-of-concept, feasibility study where 30 preterm infants on bubble CPAP with gestational age < 32+0 weeks will be recruited from the neonatal intensive care unit (NICU) at the Montreal Children's…
- Trial name
- Bubble CPAP (NCT07060833)
- Testing
- External pressure transducer, Standard microphone, Wireless acoustic sensor
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Infant, Premature, Diseases, Respiratory Insufficiency Syndrome of Newborn
Impact of CPAP Level on V/Q Mismatch in Premature Infants
Continuous positive airway pressure (CPAP) is used in premature infants to maintain lungs open and facilitate gas exchange. When ventilation/perfusion (V/Q) mismatch is present, areas of the lung that are open for gas exchange do…
- Trial name
- NCT02983825
- Testing
- Continuous positive airway pressure (CPAP); level changes
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Children's Hospital of Philadelphia
Neonatal Hypoglycemia, Infant, Small for Gestational Age
Effect of Tahneek on Hypoglycemia in Newborn Infants
Tahneek is an Arabic word which means putting something sweet such as dates, in the infant's mouth after the birth. Neonatal hypoglycemia is common in the first few days after birth.
- Conditions
- Neonatal Hypoglycemia, Infant, Small for Gestational Age, Macrosomia, Fetal, Intrauterine Growth Restriction
- Trial name
- THIN (NCT03726697)
- Testing
- Tahneek
- Where
- Saudi Arabia
- Volunteers
- 324 people
- Sponsor
- King Abdullah International Medical Research Center
Intraventricular Hemorrhage (IVH), Bleeding in the Brain
Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial
The purpose of this multicenter trial is to determine if indomethacin prevents bleeding in the brain of very low birth weight preterm infants.
- Conditions
- Intraventricular Hemorrhage (IVH), Bleeding in the Brain, Prematurity, Very Low Birth Weight Infants
- Trial name
- NCT00033917
- Testing
- indomethacin
- Where
- 3 sites in United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Yale University
PreTerm Birth, Human Milk
Protein Balance and Body Composition in Preterm Infants
The adequacy of the quality of protein supply could influence the rate and the relative composition of weight gain in very low birth weight preterm infants.
- Trial name
- NCT03013374
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Child Development, Premature Birth
Comparing Rater Reliability of Familiar Practitioners to Blinded Coders
The purpose of this study is to determine how coders who have seen multiple time points of the same dyad, and are therefore familiar with the case, rate emotional connection using the WECS compared to coders who are blinded to…
- Trial name
- NCT03680157
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Columbia University
Respiratory Distress Syndrome, Hyaline Membrane Disease
Efficacy of a New Technique -"IN-REC-SUR-E"- in Preterm Neonates With RDS
The primary hypothesis of this study is reduction in need of mechanical ventilation in the first 72 hours of life (excluding the transient tracheal intubation performed for surfactant administration and the mechanical ventilation…
- Trial name
- NCT02482766
- Testing
- Poractant alfa, 200 mg/kg, Ventilator for High-frequency Oscillatory Ventilation (HFOV), Nasal Continuous Positive Airway Pressure (nCPAP)
- Where
- 33 sites in Italy
- Volunteers
- 206 people
- Sponsor
- Catholic University of the Sacred Heart
Pregnancy Complications, Preterm Birth
Group Antenatal/Postnatal Care in Rwanda
The focus of this work is to improve antenatal care (ANC) and postnatal care (PNC) at the health center level in five districts in Rwanda (Bugesera, Burera, Nyamasheke, Nyarugenge, and Rubavu).
- Conditions
- Pregnancy Complications, Preterm Birth, Preterm Labor, Stillbirth
- Trial name
- PTBi Rwanda (NCT03154177)
- Testing
- Group ANC/PNC, Ultrasound+Pregnancy Testing
- Where
- 2 sites in Rwanda
- Volunteers
- 26,381 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.