Clinical trials: Primary Nocturnal Enuresis
Nocturnal Enuresis
A New Check-list Method for Nocturnal Enuresis
The study is aimed to demonstrate the benefits of newly formed written check-list of behavioral instructions and investigate its effects on parent's awareness, consciousness and motivation toward MNE.
- Trial name
- NCT03510975
- Testing
- desmopressin melt form 120 μg, Verbal behavioral therapy, Behavioral therapy with written check-list
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Primary Monosymptomatic Nocturnal Enuresis
Posterior Tibial Nerve Stimulation Vs Desmopressin In Children With Primary Monosymptomatic Nocturnal Enuresis
Nocturnal enuresis is a worldwide health problem frequently encountered in childhood . It affects 18 % of younger school- age children in Egypt.
- Trial name
- PTNS (NCT04545931)
- Testing
- Posterior tibial nerve stimulation, Desmopressin Acetate
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Primary Nocturnal Enuresis, Nocturnal Enuresis in Children
Effectiveness of Pelvic Floor Muscle Rehabilitation Combined With Desmopressin in Children With Primary Monosymptomatic Nocturnal Enuresis
The aim of this randomized controlled trial is to evaluate the effects of Structured Pelvic Floor Muscle Rehabilitation (SPFMR) in children with Primary Monosymptomatic Nocturnal Enuresis (PMNE) who are undergoing desmopressin…
- Trial name
- NCT06883851
- Testing
- Structured pelvic floor rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bahçeşehir University
Nocturnal Enuresis
A Study of Oral Desmopressin in Previously Untreated Children Aged 5 to 15 Years With Primary Nocturnal Enuresis
To evaluate the overall response to desmopressin treatment among previously untreated enuretic children aged 5-15 years after 3 and 6 months of treatment.
- Trial name
- DRIP (NCT00245479)
- Testing
- Primary nocturnal enuresis
- Where
- France
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Enuresis, Nocturnal
The Behavioral Therapy for Primary Monosymptomatic Nocturnal Enuresis
A prospective randomized clinical study was conducted at Urology departments, faculties of medicine, Fayoum and Cairo Universities.
- Trial name
- NCT07015320
- Testing
- urotherapy, no intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Primary Monosymptomatic Nocturnal Enuresis
Bedtime Device Restriction and Desmopressin in PMNE.
This randomized controlled trial will evaluate whether restricting bedtime digital-device use improves the response to desmopressin in children with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07776977
- Testing
- Desmopressin, Bedtime digital-device restriction
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Al-Azhar University
Nocturnal Enuresis, Nocturnal Enuresis in Children
Causes and Types of Nocturnal Enuresis in Children
Nocturnal enuresis, commonly known as bedwetting, is a frequent condition that affects many children and can have a significant impact on their self-esteem, social life, and family stress.
- Conditions
- Nocturnal Enuresis, Nocturnal Enuresis in Children, Primary Nocturnal Enuresis, Secondary Nocturnal Enuresis
- Trial name
- NCT07508111
- Volunteers
- 80 people
- Sponsor
- Assiut University
Nocturnal Enuresis in Children
Omegapres Versus Solifenacin and Mirabegron Combination Therapy in Treatment of Primary MNE
The goal of this clinical trial is to compare combination of Solifenacin and MIrabegron in treatment of primary mono-symptomatic nocturnal enuresis in children. It will also learn about the safety of that combination.
- Trial name
- NCT07199894
- Testing
- Mirabegron (beta3-adrenoceptor agonist), Anticholinergics, Desmopressin (DDAVP)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Nocturnal Enuresis
Mirabegron 25 mg for Treatment of Primary Nocturnal Enuresis
Investigators will study the efficacy and safety of mirabegron25 in treatment of primary nocturnal enuresis in comparison to oral desmopressin 120 mcg and behavioral therapy
- Trial name
- NCT05617664
- Testing
- desmopressin 120 mcg oral tablets, Mirabegron 25 MG Oral Tablet, Extended Release, behavioral therapy alone
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Benha University
Nocturnal Enuresis in Children
TENS in Nocturnal Enuresis
Paracascral transcutaneous electrical nerve stimulation (PTENS) is a credible therapeutic option for nocturnal enuresis. The investigators shall investigate whether maintenance PTENS after initial response improves durability of…
- Trial name
- NCT07594353
- Testing
- transcutaneous electrical nerve stimulation
- Volunteers
- 50 people
- Sponsor
- Suez Canal University
Primary Monosymptomatic Nocturnal Enuresis
Effectiveness of Individualized Pelvic Floor Muscle Rehabilitation in Addition to Standard Urotherapy and Alarm Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis
This study will evaluate whether adding individualized pelvic floor muscle rehabilitation to standard urotherapy and alarm treatment improves bedwetting in children aged 5-18 years with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07890194
- Testing
- Standard urotherapy, Alarm therapy, Standard urotherapy, Alarm therapy, Individualized pelvic floor muscle rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
ADHD, Primary Nocturnal Enuresis
Evaluating the Efficacy of Atomoxetine in Reducing Primary Nocturnal Enuresis in Children With ADHD: A Randomized, Placebo-Controlled Study
1. Primary Aim: To evaluate the efficacy of atomoxetine in reducing the frequency of primary nocturnal enuresis episodes in children with ADHD. 2.
- Trial name
- NCT06841666
- Testing
- Atomoxetine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Attention Deficit Hyperactivity Disorder, Enuresis
The Effect of Methylphenidate on Primary Enuresis in Children With Attention Deficit Hyperactivity Disorder
To assess wether methylphenidate reduces the prevalence of primary nocturnal enuresis in children with attention deficit disorder
- Trial name
- NCT02699528
- Testing
- methylphenidate
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Nocturnal Enuresis, Vitamin D Deficiency
Vitamin D Versus Desmopressin Versus Combination Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis and Vitamin D Deficiency
This randomized clinical trial evaluated three treatment approaches for children aged 6 to 12 years who had primary monosymptomatic nocturnal enuresis (night-time bedwetting) and confirmed vitamin D deficiency.
- Trial name
- NCT07292753
- Testing
- Vitamin D, Desmopressin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Daytime Urinary Incontinence, Urinary Frequency
Micturition Desire-Relaxation Training Device for Lower Urinary Tract Dysfunction in Children
Urine storage and voiding are fundamental physiological processes. In clinical settings, many cases of lower urinary tract dysfunction (LUTD) are closely associated with abnormal conditioned reflexes formed in the central nervous…
- Conditions
- Daytime Urinary Incontinence, Urinary Frequency, Lower Urinary Tract Dysfunction, Primary Nocturnal Enuresis
- Trial name
- ICCS，LUTD，PNE (NCT07000656)
- Testing
- Micturition Desire-Relaxation Training Device
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Children's Medical Center
Nocturnal Enuresis
Aromatherapy Versus Diet
Eligible children were randomly divided into 2 groups assigned to receive dietary recommendations (group A) or to receive herbal compounds (group B).
- Trial name
- NCT06853379
- Testing
- dietary recommendations, aroma therapy
- Volunteers
- 30 people
- Sponsor
- Cairo University
Nocturnal Enuresis in Children, Primary Nocturnal Enuresis
Potential Adjuvant Therapies for Children With Primary Nocturnal Enuresis
To examine the possible reduction in dietary salt intake on the outcomes of nocturnal enuresis
- Trial name
- NCT07876947
- Testing
- Dietary Salt Restriction, Omega Supplementation
- Volunteers
- 100 people
- Sponsor
- Cairo University
Primary Nocturnal Enuresis
A 6-week Open Label Cross-over Study With 2 Different Daily Doses of Minirin® Oral Lyophilisate in Children and Adolescents With Primary Nocturnal Enuresis (PNE)
To evaluate the preference of subjects for Minirin® oral lyophilisate treatment compared with Minirin® tablet treatment after 6 weeks.
- Trial name
- PALAT (NCT00209261)
- Testing
- MINIRIN Oral Lyophilisate, Minirin tablet
- Where
- France
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Enuresis
Family Help Program: Nighttime Enuresis Treatment Program
The purpose of the Strongest Families (formerly Family Help Program)is to evaluate the effectiveness of the Strongest Families distance intervention compared to usual or standard care that is typically provided to children with…
- Trial name
- NCT00270621
- Testing
- FHP Night time ENuresis Intervention
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Primary Nocturnal Enuresis
A Cohort Study on Treating Primary Nocturnal Enuresis by Regulating Central-Peripheral Circadian Rhythm
Primary nocturnal enuresis (PNE), a prevalent pediatric disorder, suffers from therapeutic limitations characterized by low efficacy and high relapse rates.
- Trial name
- NCT07003126
- Testing
- Circadian Rhythm Intervention Combined with Bladder Training, Bladder Training (basic treatment for enuresis)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Children's Medical Center