Clinical trials: Primary Nocturnal Enuresis
Nocturnal Enuresis
A New Check-list Method for Nocturnal Enuresis
The study is aimed to demonstrate the benefits of newly formed written check-list of behavioral instructions and investigate its effects on parent's awareness, consciousness and motivation toward MNE.
- Trial name
- NCT03510975
- Testing
- desmopressin melt form 120 μg, Verbal behavioral therapy, Behavioral therapy with written check-list
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Nocturnal Enuresis
The Safety and Efficacy of Fluoxetine for Refractory Primary Mono-symptomatic Nocturnal Enuresis in Children
To determine whether there is a role for the selective serotonin reuptake inhibitors, fluoxetine, as therapy in the treatment of refractory primary monosymptomatic nocturnal enuresis in children , and whether there are side…
- Trial name
- NCT04676139
- Testing
- Fluoxetine
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Nocturnal Enuresis in Children
TENS in Nocturnal Enuresis
Paracascral transcutaneous electrical nerve stimulation (PTENS) is a credible therapeutic option for nocturnal enuresis. The investigators shall investigate whether maintenance PTENS after initial response improves durability of…
- Trial name
- NCT07594353
- Testing
- transcutaneous electrical nerve stimulation
- Volunteers
- 50 people
- Sponsor
- Suez Canal University
Nocturnal Enuresis, Vitamin D Deficiency
Vitamin D Versus Desmopressin Versus Combination Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis and Vitamin D Deficiency
This randomized clinical trial evaluated three treatment approaches for children aged 6 to 12 years who had primary monosymptomatic nocturnal enuresis (night-time bedwetting) and confirmed vitamin D deficiency.
- Trial name
- NCT07292753
- Testing
- Vitamin D, Desmopressin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Meatal Stenosis, Primary Nocturnal Enuresis
Hidden Link Between Meatal Stenosis and Primary Nocturnal Enuresis in Children
This study aimed to investigate the association between meatal stenosis and primary nocturnal enuresis severity, and evaluated therapeutic outcomes following surgical correction.
- Conditions
- Meatal Stenosis, Primary Nocturnal Enuresis, Children
- Trial name
- NCT07424651
- Testing
- Meatoplasty Primary nocturnal enuresis.
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- New Valley University
Enuresis
A Study to Determine if Ibuprofen in Combination With Pseudoephedrine HCl is More Effective Than Each Drug Alone in the Treatment of Nighttime Bedwetting
The purpose of the study is to determine if ibuprofen in combination with pseudoephedrine HCl in the treatment of nightime bedwetting in children is more effective than each drug alone and if the individual drugs are more…
- Trial name
- NCT00240812
- Testing
- ibuprofen; pseudoephedrine HCl
- Volunteers
- 318 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Enuresis, Nocturnal
Comparative Study of the Efficacy of TENS Versus Placebo in Isolated Primary Enuresis
Nocturnal enuresis is a functional urinary disorder in children. It is intermittent urinary incontinence during sleep in children aged 5 years and older.
- Trial name
- TENS-Enuresis (NCT04413461)
- Testing
- TENS
- Where
- 4 sites in France
- Volunteers
- 54 people
- Sponsor
- Fondation Lenval
Primary Nocturnal Enuresis
A 6-week Open Label Cross-over Study With 2 Different Daily Doses of Minirin® Oral Lyophilisate in Children and Adolescents With Primary Nocturnal Enuresis (PNE)
To evaluate the preference of subjects for Minirin® oral lyophilisate treatment compared with Minirin® tablet treatment after 6 weeks.
- Trial name
- PALAT (NCT00209261)
- Testing
- MINIRIN Oral Lyophilisate, Minirin tablet
- Where
- France
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Primary Nocturnal Enuresis
A Cohort Study on Treating Primary Nocturnal Enuresis by Regulating Central-Peripheral Circadian Rhythm
Primary nocturnal enuresis (PNE), a prevalent pediatric disorder, suffers from therapeutic limitations characterized by low efficacy and high relapse rates.
- Trial name
- NCT07003126
- Testing
- Circadian Rhythm Intervention Combined with Bladder Training, Bladder Training (basic treatment for enuresis)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Children's Medical Center
Overactive Bladder Syndrome, Enuresis, Nocturnal
Overactive Bladder Syndrome
Purpose: A lot of etiological factors related to overactive bladder (OAB) has been investigated. However, the role of primary nocturnal enuresis (NE), which is characterized with childhood night time incontinence, in the etiology…
- Trial name
- NCT05151081
- Testing
- basicly
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people
- Sponsor
- Hisar Intercontinental Hospital
Nocturnal Enuresis
MINRIN® Orally Disintegrating Tablet (Fast Dissolving Desmopressin) and Tablets in Treatment of Primary Nocturnal Enuresis
Desmopressin in treatment of nocturnal enuresis (bedwetting).
- Trial name
- MELT (NCT01368913)
- Where
- 73 sites in Germany
- Volunteers
- 138 people
- Sponsor
- Ferring Pharmaceuticals
Enuresis, Nocturnal, Ganglion
Ganglion Cell Thickness in Enuresis Nocturna
The precise role of the intrinsic circadian regulatory mechanism behind the pathogenesis of enuresis is not fully understood, but in theory, circadian rhythm irregularity may be the primary pathogenic mechanism not only for…
- Conditions
- Enuresis, Nocturnal, Ganglion, Circadian Rhythm Disorders
- Trial name
- NCT05126732
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Bakircay University
Primary Monosymptomatic Nocturnal Enuresis
Bedtime Device Restriction and Desmopressin in PMNE.
This randomized controlled trial will evaluate whether restricting bedtime digital-device use improves the response to desmopressin in children with primary monosymptomatic nocturnal enuresis.
- Trial name
- NCT07776977
- Testing
- Desmopressin, Bedtime digital-device restriction
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Al-Azhar University
Nocturnal Enuresis, Nocturnal Enuresis in Children
Causes and Types of Nocturnal Enuresis in Children
Nocturnal enuresis, commonly known as bedwetting, is a frequent condition that affects many children and can have a significant impact on their self-esteem, social life, and family stress.
- Conditions
- Nocturnal Enuresis, Nocturnal Enuresis in Children, Primary Nocturnal Enuresis, Secondary Nocturnal Enuresis
- Trial name
- NCT07508111
- Volunteers
- 80 people
- Sponsor
- Assiut University
Nocturnal Enuresis in Children, Primary Nocturnal Enuresis
Potential Adjuvant Therapies for Children With Primary Nocturnal Enuresis
To examine the possible reduction in dietary salt intake on the outcomes of nocturnal enuresis
- Trial name
- NCT07876947
- Testing
- Dietary Salt Restriction, Omega Supplementation
- Volunteers
- 100 people
- Sponsor
- Cairo University
Epilepsy, Nocturnal Enuresis
Sleep Architecture in Valproate-induced Nocturnal Enuresis in Primary School and Preschool Children.
Our study, retrospectively evaluate the characteristics of and the risk factors for the occurrence of nocturnal enuresis in epileptic children kept on valproate monotherapy.
- Trial name
- NCT04191863
- Testing
- Clinical, EEG and laboratory assessment at presentation, Valproate
- Where
- Egypt
- Volunteers
- 260 people
- Sponsor
- Mansoura University Hospital
Enuresis, Nocturnal
The Behavioral Therapy for Primary Monosymptomatic Nocturnal Enuresis
A prospective randomized clinical study was conducted at Urology departments, faculties of medicine, Fayoum and Cairo Universities.
- Trial name
- NCT07015320
- Testing
- urotherapy, no intervention
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Nocturnal Enuresis
A Study of Oral Desmopressin in Previously Untreated Children Aged 5 to 15 Years With Primary Nocturnal Enuresis
To evaluate the overall response to desmopressin treatment among previously untreated enuretic children aged 5-15 years after 3 and 6 months of treatment.
- Trial name
- DRIP (NCT00245479)
- Testing
- Primary nocturnal enuresis
- Where
- France
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Primary Nocturnal Enuresis
Desmopressin Response in the Young
The purpose of this study is to determine whether desmopressin administered as a melt tablet is effective in reducing the number of wet nights in children and adolescents who suffer from bedwetting.
- Trial name
- DRY (NCT00230594)
- Testing
- desmopressin
- Where
- 9 sites in Canada
- Volunteers
- 132 people
- Sponsor
- Ferring Pharmaceuticals
Nocturnal Enuresis
Aromatherapy Versus Diet
Eligible children were randomly divided into 2 groups assigned to receive dietary recommendations (group A) or to receive herbal compounds (group B).
- Trial name
- NCT06853379
- Testing
- dietary recommendations, aroma therapy
- Volunteers
- 30 people
- Sponsor
- Cairo University