Clinical trials: Procalcitonin
Infection
Biological Markers for the Diagnosis of Central Nervous System Infective Diseases
Bacterial meningitis is a potentially life-threatening disease that is associated with substantial neurological morbidity and mortality. Accurate diagnosis is essential to improve outcome and prevent antibiotic overuse.
- Trial name
- NCT02278016
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Sepsis
Diagnostic and Prognostic Value of Serial Procalcitonin (PCT) Measurements in Critically Ill Patients
In 2005, the Food and Drug Administration (FDA) approved procalcitonin in conjunction with other laboratory markers to aid in the risk assessment of critically ill patients with severe infection (sepsis).
- Trial name
- PCT (NCT01362920)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Cleveland Clinic
Immunization
Effect of Infant Immunization on Procalcitonin Levels - A Pilot Study
Fever is a well-known side effect of immunizations. When a febrile infant presents to a healthcare site, such as an emergency room, a large number of tests are usually performed, which may include a procalcitonin (PCT) level.
- Trial name
- NCT04295694
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Pneumonia, Pediatric Respiratory Diseases
Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia
This pilot study will evaluate study processes and feasibility of a future large-scale clinical trial that proposes to test whether low-risk children managed as outpatients with community-acquired pneumonia (CAP) and…
- Conditions
- Pneumonia, Pediatric Respiratory Diseases, Antibiotic Use, Community-acquired Pneumonia
- Trial name
- PRAPP (NCT04963764)
- Testing
- Amoxicillin
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Sepsis - to Reduce Mortality in the Intensive Care Unit
Procalcitonin Increase Identifies Critically Ill Patients at High Risk of Mortality
Procalcitonin, a marker of infection has often been compared to clinical pictures as for instance "clinical sepsis". This has given som problems in the interpretation of these studies, because of the lack of good Gold Standards…
- Trial name
- NCT00144638
- Where
- Denmark
- Volunteers
- 450 people
- Sponsor
- Danish Procalcitonin Study Group
Fever Without Source
Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without Source
Because a newly available point-of-care test may have real interest especially for children in the Emergency Department (ED) setting, by limiting painful and stressful venipunctures and decreasing the length of stay in the ED…
- Trial name
- DIAFEVER (NCT03607162)
- Testing
- DIAFEVER algorithm
- Where
- 26 sites in France, Switzerland
- Volunteers
- 4,928 people
- Sponsor
- Nantes University Hospital
Procalcitonin, Fever Without Source
Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a Source
Serious bacterial infections are often difficult to detect in children with fever without source. Procalcitonin is a better blood marker of infection than White blood cell count and possibly than C-reactive protein.
- Conditions
- Procalcitonin, Fever Without Source, Bacterial Infection, Bacteremia
- Trial name
- NCT00692848
- Testing
- Procalcitonin dosage PCT-Q test (Brahms, Germany)
- Where
- Canada
- Volunteers
- 384 people
- Sponsor
- St. Justine's Hospital
Arthritis, Infectious
Pro-calcitonin for Early Detection of Septic Arthritis
Background: Children presenting with non-traumatic joint pain require different treatment depending on the cause of pain. Septic arthritis, which results from a bacterial infection in the joint, often requires a surgical…
- Trial name
- NCT02085733
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
CNS Infection in Children
The Role of Serum Procalcitonin in Diagnosis and Detection of Outcome of Acute Bacterial Meningitis in Childern
Meningitis is one of the most common central nervous system (CNS) infections encountered in infants and children. The source of infection in meningitis can be bacterial, viral, fungal, or parasitic in origin .
- Trial name
- NCT04929925
- Testing
- serum procalcitonin in acute bacterial meningitis
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Meningitis in Children
Role of CSF-CRPand Serum Procalcitonin in Differentiation Between Bacterial and Viral Meningitis in Children
Meningitis is one of the major lethal infectious diseases especially for the children in developing countries .It is not always possible and often very difficult to distinguish between bacterial and viral meningitis according to…
- Trial name
- NCT03387969
- Testing
- CSF sample
- Volunteers
- 80 people
- Sponsor
- Assiut University
Pneumonia Childhood
Severe Pneumonia Diagnostic in Pediatric Population by Lung Ultrasonography and Procalcitonin
Lung ultrasound (LUS) in combination with a biomarker has not yet been studied. The investigators propose a clinical trial where the primary aims are: 1.
- Trial name
- PROLUSP (NCT04217980)
- Testing
- Lung ultrasonography (LUS) or Chest X ray (CXR)
- Where
- 2 sites in Spain
- Volunteers
- 202 people
- Sponsor
- Fundació Sant Joan de Déu