Clinical trials: Prostate
Breast Neoplasms, Ovarian Neoplasms
Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
The purpose of this study is to better understand the genetic causes of cancer and the inherited tendency to develop cancer. To accomplish this, blood specimens and/or saliva samples and/or tumor and normal tissue blocks from…
- Conditions
- Breast Neoplasms, Ovarian Neoplasms, Colonic Neoplasms, Prostatic Neoplasms
- Trial name
- NCT00579163
- Where
- United States
- Volunteers
- 992 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostatic Hyperplasia
Drug Use Investigation for AVOLVE(BPH)
The study is designed to investigate the safety and efficacy of dutasteride capsules 0.5 mg collected from the required number of Japanese subjects with benign prostatic hyperplasia (BPH) in order to identify concerns or…
- Trial name
- NCT01376284
- Testing
- Dutasteride
- Volunteers
- 1,000 people
- Sponsor
- GlaxoSmithKline
Prostate Cancer
Leuprolide, Bicalutamide, and Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer After External-Beam Radiation Therapy
RATIONALE: Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as leuprolide and bicalutamide, may lessen the amount of androgens made by the body.
- Trial name
- NCT00684905
- Testing
- bicalutamide, leuprolide acetate, adjuvant therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Prostate Cancer
Evaluation Ultrasound Elasticity/Tissue Strain-Hardening Imaging for Prostate Cancer Patients Undergoing Radical Prostatectomy
The primary objective is to perform a pilot trial evaluation of a novel prostate ultrasound imaging software utilizing tissue elasticity measurements to identify tumor foci among men who will undergo radical prostatectomy for…
- Trial name
- NCT00824902
- Testing
- Tissue Elastography Imaging
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- M.D. Anderson Cancer Center
Elevated PSA, Prostate Cancer
Prospective Assessment of Image Registration for the Diagnosis of Prostate Cancer
This is a pilot study to determine cancer detection rate of conventional/systematic versus targeted biopsy methods in diagnosis of potentially lethal prostate cancer.
- Trial name
- Paired Cap (NCT02425228)
- Testing
- Targeted biopsy
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Trial Comparing Radical Radiotherapy to Prostate Only VS Prostate And Pelvic Lymph Nodes in Intermediate And High Risk Prostate Cancer
This phase II randomized controlled study aims to compare the treatment results of intermediate and high risk prostate cancer patients treated with hormonal therapy and radical radiotherapy with or without pelvic lymph nodes in…
- Trial name
- NCT05285319
- Testing
- Prostate Only Radiation, Prostate and Pelvic Lymph Node Radiation
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Cairo University
PSMA Positive Tumors or Tumor Tissues
PSMA-specific CAR-T Cell Therapy
The purpose of this clinical trial is to assess the feasibility, safety and efficacy of PSMA-specific CAR-T cell therapy in patients with PSMA positive tumor.
- Trial name
- NCT04429451
- Testing
- 4SCAR-PSMA T cells
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shenzhen Geno-Immune Medical Institute
Prostate Cancer
Triptorelin, Flutamide, and External-Beam Radiation Therapy or External-Beam Radiation Therapy Alone in Treating Patients With Stage II or Stage III Prostate Cancer
RATIONALE: Androgens can cause the growth of prostate cancer cells. Drugs, such as triptorelin and flutamide, may stop the adrenal glands from making androgens. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Trial name
- NCT00104741
- Testing
- flutamide, triptorelin, radiation therapy
- Where
- 31 sites in France
- Volunteers
- 378 people
- Sponsor
- UNICANCER
Benign Prostatic Hyperplasia
Pelvic Floor Muscle Exercise for Lower Urinary Tract Symptoms After Surgery for Benign Prostatic Hyperplasia.
This study aims to evaluate the effectiveness of pelvic floor muscle exercise (PFME) on improving lower urinary tract symptoms (LUTS), postvoid residual volume (PVR), and quality of life in patients undergoing surgery for benign…
- Trial name
- BPH LUTS PFME (NCT07293442)
- Testing
- pelvic floor muscle exercises
- Where
- 2 sites in Taiwan
- Volunteers
- 46 people
- Sponsor
- Taipei Medical University WanFang Hospital
Prostate Cancer
Clinical Data Collection of Patients Treated With High Intensity Focused Ultrasound (HIFU) by the Focal One for Their Prostate Cancer.
The aim of the registry is to gather real-life data to evaluate the clinical performance and safety of medical devices in patients who have been treated with HIFU thank to the Focal One device for their prostate cancer.
- Trial name
- One registry (NCT07645872)
- Where
- 5 sites in France
- Volunteers
- 3,000 people
- Sponsor
- EDAP TMS S.A.
Prostate Cancer
Prostate Cancer Localization With a Multiparametric Magnetic Resonance (MR) Approach
The primary objective of this prospective multi-centre study is to prove the diagnostic accuracy of in vivo 3T multi-modality Magnetic Resonance Imaging (high resolution T2-weighted MRI, DCE-MRI, MRSI and DWI techniques) in…
- Trial name
- PCa-MAP (NCT01138527)
- Testing
- MRI examination
- Where
- 9 sites in United States, Austria and 6 more
- Volunteers
- 148 people
- Sponsor
- Radboud University Medical Center
Lower Urinary Track Symptoms, Benign Prostate Obstruction (BPO)
Outcome and Patient Experiences After Transurethral Resection and Bipolar Enucleation of the Prostate - a Multi-center, Randomized Controlled Trial.
In this randomized controlled trial, we will evaluate if bipolar enucleation of the prostate (BEEP) is associated with better urinary voiding outcome than transurethral resection (TURP) in men with enlarged prostate referred to…
- Trial name
- NCT07562386
- Testing
- Transurethral resection of the prostate., Bipolar enucleation of the prostate
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
Metastatic Prostate Cancer
PULSE Registry: for Patients Receiving Lutetium (177Lu) Vipivotide Tetraxetan
The primary objective of the study is to describe real-world drug utilisation of lutetium (177Lu) vipivotide tetraxetan among patients with metastatic prostate cancer
- Trial name
- PULSE (NCT07484269)
- Where
- Switzerland
- Volunteers
- 753 people
- Sponsor
- Novartis Pharmaceuticals
Prostate Cancer, Metabolic Syndrome
Fasting Mimicking Diet in Prostate Cancer and Metabolic Syndrome
This is a prospective observational cohort study of patients with prostate cancer who have a metabolic syndrome. The study aims to evaluate the role of intermittent fasting (fasting mimicking diet) in these patients.
- Conditions
- Prostate Cancer, Metabolic Syndrome, Intermittent Fasting
- Trial name
- NCT04292041
- Testing
- Fasting mimicking diet
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Galway Clinic
Prostate Cancer
Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Giving radiation therapy in different ways may kill more tumor cells.
- Trial name
- NCT00258466
- Testing
- radiation therapy
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Prostate Cancer, Evidence Based Medicine
A Cluster Package Intervention to Promote an Evidence-based Use of PSA-tests in General Practice
It is widely acknowledged that prostate specific antigen (PSA) testing can lead to false-positives, overdiagnosis and overtreatment of prostate cancer.
- Conditions
- Prostate Cancer, Evidence Based Medicine, Prostate Specific Antigen
- Trial name
- NCT06748456
- Testing
- Podcast, Cluster meeting, Hand-out material 1
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Copenhagen
Prostate Cancer
Longitudinal Assessment of Health-Related Quality of Life in Men With Localized Prostate Cancer
The purpose of this study is to assess quality-of-life of men with prostate cancer. "Quality-of-life" means how you feel about your life as a result of your disease and its treatment.
- Trial name
- NCT00582842
- Testing
- Interview, survey instruments using Web-Based Data Collection System (WBDC) survey content
- Where
- 5 sites in United States
- Volunteers
- 1,800 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Adenocarcinoma of Prostate
Impact of Local Anesthesia Type on Cancer Detection Rate in Transrectal Ultrasound Guided Prostate Biopsy
Transrectal ultrasound guided prostate biopsy (TRUS-Bx) is the gold standard method for prostat cancer diagnosis. Cancer detection rate is an important issue in TRUS-Bx.
- Trial name
- NCT02025361
- Testing
- intrarectal lidocaine gel, periprostatic nerve blockade
- Where
- Turkey (Türkiye)
- Volunteers
- 422 people
- Sponsor
- Bagcilar Training and Research Hospital
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer
Early Stage Prostate Cancer Cohort
Environmental factors such as diet and cigarette smoking may play a role in predicting the progression of early stage prostate cancer to advance disease.
- Trial name
- NCT00011349
- Where
- 13 sites in United States
- Volunteers
- 1,116 people
- Sponsor
- US Department of Veterans Affairs